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A mouse monoclonal antibody (MAB 9,9) to coagulation factor IX (F.IX) detects a polymorphism in the plasma of normal people. Its epitope has been narrowed down to <6 amino acids in the activation peptide of the X-linked F.IX protein. The activation peptide contains a dimorphism - Thr:Ala - at position 148 of the protein. Using synthetic oligonucleotides, we have demonstrated that (1) the F.IX whic
ABSTRACTAs a part of a democratic demand for transparency in urban development processes it is important that design professionals hold the ability to scrutinise their own work process, and at certain stages let go of predefined ideas of future realities. This work revolves around how design professionals perceive options for design in such situations. A basic assumption in this work is that a des
While there is general agreement on the necessity tomeasure glomerular filtration rate (GFR) inmany clinical situations, there is less agreement on the bestmethod to achieve this purpose. As the gold standardmethod for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtrationmarkers and protocols compete to re
A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the onl
BACKGROUND: Effective T-cell depletion is a prerequisite for haploidentical peripheral blood progenitor cell (PBPC) transplantation. This study was performed to investigate the performance of magnetic cell sorting–based direct large-scale T-cell depletion, which is an attractive alternative to standard PBPC enrichment procedures. STUDY DESIGN AND METHODS: PBPCs were harvested from 11 human leukoc
Immigrants, particularly unskilled ones from less developed countries, are identified as one of the most vulnerable groups worldwide. They face various difficulties in order to integrate into their new countries in virtue of cultural differences and inadequate competence and knowledge. An increasing group of them are excluded from the labour market and society which in turn exacerbate their vulner
The European Union aims at being an ethical actor on the global arena and the EU development-policy is directed towards achieving long-term socio-economic development, with a specific focus on Sub-Saharan Africa, where development is showing little progress, and food security and agricultural development is at the top of the agenda. The EU is both the biggest market and the biggest aid-donor for
Abstract Failures in achieving the 2010 goals of slowing down or halting the loss of biodiversity, and the setting of new biodiversity targets set for 2020, stress an urgent need to expand current reserve networks and to improve their effectiveness in protecting species and habitats. Habitat suitability models, and derived maps from them, are among the broadest used tools for identifying the ecol
The purpose of this study is to explore whether communicating the liabilities of newness can justify young ventures’ offshoring decisions to such an extent that it moderates country-of-origin (COO) effects. We adjust the established concept of COO effects to the entrepreneurial context and therefore include the country of ownership (CO) instead of the country of design (CD) next to the commonly us
Research question: How can the participation in the COII support companies to open up? Methodology: The thesis applies a single case study design to examine an opening up process in relation to open innovation. The thesis used a qualitative research strategy with inductive design with influences of deduction. The primary data emerged from semi-structured interviews to grasp an in-depth understand
The aim of this study is to examine how women have proceeded to end an abusive relationship, the support and help they received and whether there were any difficulties during this procedure. Our study is based on qualitative interviews with six women. All of the women are over 18 years old and have been out of the relationship for more than two years. The data is analyzed based on thematic analysi
Human-induced climate change continues to have a disproportionate negative impact on people and the planet. The human dimension must be included to make a change to reduce the environmental challenges we are facing. As mobile digital technologies have developed, the use of gamification has emerged as a way to promote pro-environmental behavior. As the field is relatively new, the research on the t
Human Capital is deemed as an imperative factor for economic growth, however, it is argued the extent of this interrelation. Acemoglu, Gallego and Robinson (2014) claim that the institutional framework of a nation, in specificthose of private property are deemed as pivotal for a nation’s development. In this sense, in order to contectualise this argument, the current thesis focuses on the case of
In this paper, we investigate the predictive performance of eight common Value at Risk (VaR) estimation methods with the daily data of OMX Stockholm 30 and FTSE 100 indexes. These methods include non-parametric, parametric as well as Extreme Value Theory approaches whose daily and 10-day estimates are then evaluated using the Christoffersen frequency test. The reason why we choose these two stock
The U.S.-China relationship is undeniably one of the most important economic and security relationships of the 21st century. Since Barack Obama took office in 2009, increasing emphasis has been put on ending the two wars in the Middle East and to redirect focus towards the increasingly important Asia Pacific region. The U.S. relationship with China has proven difficult to manage, and major differi
Globaliseringen och den teknologiska utvecklingen som nya möjligheter innebär en teknologi som producerar elektroniskt avfall. Industriländerna producerar, konsumerar och tar del av förtjänsterna för att sedan olagligt transportera avfallet till utvecklingsländer. I samband med dumpning av elektroniskt avfall uppkommer risker vilka vi ämnar att undersöka. För att förstå konsekvenserna av dumpninge
Title: Leadership Driving Successful Implementation of Continuous Improvement Programs - A Case Study Using the Path Goal Model Authors: Johanna Gustafsson, Paulina Hornay Supervisors: Stein Kleppestø, Ph.D., Associate professor, Department of Business Administration, School of Economics and Management, Lund University. Peter Berling, Associate professor, Department of Industrial Management an
