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A search for the pair production of top squarks, each with R-parity-violating decays into two Standard Model quarks, is performed using 17.4 fb−1 of √s = 8 TeV proton-proton collision data recorded by the ATLAS experiment at the LHC. Each top squark is assumed to decay to a b- and an s-quark, leading to four quarks in the final state. Background discrimination is achieved with the use of b-tagging
A total of 1280 80-year-old men were invited to a medical examination to study common risk indicators for cardiovascular disease (CVD) in the elderly. From the pool of 811 responders (63.3%), all 122 individuals who fulfilled our inclusion criteria were assigned to one of four groups: (1) no CVD, non-smokers; (2) no CVD, smokers; (3) CVD, smokers; (4) CVD, non-smokers. A telephone interview with 7
Aims: To test the hypothesis that there is lower prevalence of islet antibodies in subjects with newly diagnosed Type 1 diabetes mellitus in young adulthood than in children is associated with less severe diabetes at time of diagnosis. Methods: This investigation was based on a nationwide study (Diabetes Incidence Study in Sweden) of 15-34-year-old newly diagnosed diabetic subjects. During 1992-19
Inherited resistance to activated protein C (APC-resistance), caused by a point mutation in the factor V gene leading to replacement of Arg(R)506 with a Gln (Q), and inherited protein S deficiency are associated with functional impairment of the protein C anticoagulant system, yielding lifelong hypercoagulability and increased risk of thrombosis. APC-resistance is often an additional genetic risk
Triple-negative breast cancer (TNBC) is associated with poor prognosis and no targeted treatments are available for TNBC. Drugs inhibiting tyrosine kinases, such as vascular endothelial growth factor receptor 2 (VEGFR2) and KIT, have shown some promising results for patients with TNBC. The aim of the study was to investigate whether gains and/or amplifications of VEGFR2 and KIT, located at 4q12, o
OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>
Numerous publications have described the importance of Bone Morphogenetic Protein (BMP) signaling in the specification of hematopoietic tissue in developing embryos. Here we investigate the full role of canonical BMP signaling in both adult and fetal liver hematopoiesis using conditional knockout strategies, since conventional disruption of components of the BMP signaling pathway result in early d
The purpose of this dissertation is to evaluate the effectiveness and cost-effectiveness of Multisystemic Therapy (MST) in Sweden. This evaluation is set against the background of evidence-based social work practice and is organized around four separate but interrelated studies. The first of these studies used program theory reconstruction to investigate three conceptualizations of evidence-based
Three patients with a failed total ankle arthroplasty underwent tibiocalcaneal arthrodesis. In an attempt to preserve leg length, a titanium cage filled with autologous bone was placed in the defect. None of the ankles healed primarily. After 9 to 29 months, the cages, which only contained necrotic material, were removed and repeat arthrodesis was performed using a retrograde intramedullary nail.
In today's world, so much knowledge is developed through a steady stream of short research projects that longer ones are becoming more unusual. That is why we decided to pause and look back over the seven-year-long joint endeavor between The Pictorium and Certec. This was also seen as a short-term project from the beginning. What has sustained it over the years? The answer surprised even us: its s
OBJECTIVE: To develop a diet quality index (DQI) that assesses adherence to the Swedish nutrition recommendations (SNR) and the Swedish dietary guidelines (SDG). DESIGN: A cross-sectional study within the Malmö Diet and Cancer (MDC) cohort. A diet history method collected dietary data, a structured questionnaire lifestyle and socio-economic information, and anthropometric data were collected by di
Effluent wastewater contains organic micropollutants (OMPs) that harm aquatic ecosystems. Therefore, wastewater treatment plants (WWTPs) need to expand their facilities with advanced water treatment technologies. Water scarcity and improved effluent quality is encouraging the reuse of treated effluent. This study thus has a dual purpose: first, to evaluate OMP removal using two technique combinati
Background: Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with lower bone mineral content (BMC) and density (BMD) in children, but prospective studies remain limited. We aimed to investigate associations between prenatal and childhood PFAS exposure and BMC/BMD at age 9 years, following up on our previous findings from age 7 years. Methods: We used data from the Odense
Background: Prolonged time to surgery (TTS) after neoadjuvant chemoradiotherapy (nCRT) may enable malnourished oesophageal cancer patients' nutritional status to recover better, possibly improving outcomes with fewer complications and better overall survival (OS) after oesophagectomy. Methods: This is a substudy within a multicentre randomised controlled trial comparing outcomes in patients with o
Ensuring high vaccination coverage is vital, particularly during a pandemic. While pre-booked appointment letters have shown promise in vaccination campaigns, their effectiveness in specific sociodemographic groups remains to be explored. Our study evaluated the effect of pre-booked appointment letters on COVID-19 vaccine uptake within different sociodemographic groups using a quasi-experimental m
Global climate models (GCMs) are challenged by difficulties in simulating cloud phase and cloud radiative effect over the Southern Ocean (SO). Some of the new-generation GCMs predict too much liquid and too little ice in mixed-phase clouds. This misrepresentation of cloud phase in GCMs results in weaker negative cloud feedback over the SO and a higher climate sensitivity. Based on a model comparis
A piece of lead with imprints from a coin die and the early minting in Lund. At an archaeological excavation in central Lund in the early 1970s a very unusual find was retrieved: a piece of lead with several imprints from a coin die. The motif and the runic inscription on the lead plate indicate that the die derives from Sven Estridsen’s minting during his late years as king of Denmark. The find i
