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Abstract:Background:The need for vascular procedures for certain disease-specific causes is a majorissue for health care today. This thesis will focus on endovascular treatmentfor PAD and malfunctioning haemodialysis access. Although many other vasculardiseases and anatomic regions sometimes need to be managed with endovascularprocedures, PAD and haemodialysis access together account for a signifi
BackgroundThis study aimed to investigate the exposure to perfluoroalkyl substances (PFAS) and cancer-related toxicity in workers in different Swedish industry sectors with exposures to hexavalent chromium (Cr(VI)).MethodsThe study consisted of 111 exposed workers and 72 controls. The exposed workers were performing manufacture/processing of metal products (n=55), working in steel production (n=31
Because global sea level during the last interglacial (LIG; 130–115 ka) was higher than today, the LIG is a useful approximate analogue for improving predictions of future sea-level rise. Here, we synthesize sea-level proxies for the LIG in the glaciated Northern Hemisphere for inclusion in the World Atlas of Last Interglacial Shorelines (WALIS) database.We describe 82 sites from Russia, northern Because global sea level during the last interglacial (LIG; 130–115 ka) was higher than today, the LIG is a useful approximate analogue for improving predictions of future sea-level rise. Here, we synthesize sea-level proxies for the LIG in the glaciated Northern Hemisphere for inclusion in the World Atlas of Last Interglacial Shorelines (WALIS) database. We describe 82 sites from Russia, northern
BACKGROUND: The aim of this study was to examine the impact of insulin sensitivity and muscle fibre composition to exercise capacity in individuals with type 2 diabetes (T2D), impaired glucose tolerance (IGT) and normal glucose tolerance (NGT). METHODS: Thirty-nine male patients with T2D, 44 male subjects with IGT and 58 subjects with NGT matched for age, weight and body mass index (BMI) participa
Abstract L-DOPA-induced dyskinesia in Parkinson's Disease (PD) is associated with large increases in brain dopamine (DA) levels following drug dosing, but the precise significance of this phenomenon is not understood. Here we compare DA efflux and metabolism in the striatum and the substantia nigra (SN) in dyskinetic and non-dyskinetic animals following a standard dose of L-DOPA. Rats with 6-OHDA
Previous research has focused on how governments and public authorities can limit civil society organisations’ (CSOs) autonomy by shrinking their operational civic space and their democratic functions. There has been less attention paid to how other external actors and types of pressure might restrict access to civic space and how it can induce coping responses on both an individual and organizati
Introduction TCP-25 gel is intended for use in treatment of wound infection and inflammation. Current local therapies for wounds have limited efficacy to prevent infections and there are no wound treatments available today that target the excessive inflammation that often hampers wound healing in both acute and chronic wounds. There is therefore a high medical need for new therapeutic alternatives
The 17 UN Sustainable Development Goals (SDGs) provide a framework for “peace and prosperity for people and the planet, now and into the future” (UN, 2015). Fast-moving societal questions as the ones related to the SDGs are often addressed from within traditional disciplinary research paradigms, which might not be best equipped for tackling the emerging challenges. At Lund University, an interdiscThe 17 UN Sustainable Development Goals (SDGs) provide a framework for “peace and prosperity for people and the planet, now and into the future” (UN, 2015). Fast-moving societal questions as the ones related to the SDGs are often addressed from within traditional disciplinary research paradigms, which might not be best equipped for tackling the emerging challenges. At Lund University, an interdisc
The Siljan region hosts Europe´s largest impact structure. The high-relief landscape, with a central granite dome bordered by lake basins, contains an array of glacial and shore-level landforms. We investigated its deglaciation history by mapping and analysing landforms on high resolution LiDAR-based Digital Surface Models coupled with well-dated sediment successions from peat and lake sediment co
Background: Well-established associations exist between the risk of small for gestational age (SGA) and unidimensional sociodemographic factors. We investigated social inequalities in SGA risk and adopted an intersectional approach that simultaneously considers different social categories. By doing so, we could assess heterogeneities in SGA risk within unidimensional sociodemographic categories. M
Background: Previous gene-environment interaction studies of breast cancer risk have provided sparse evidence of interactions. Using the largest available dataset to date, we performed a comprehensive assessment of potential effect modification of 205 common susceptibility variants by 13 established breast cancer risk factors, including replication of previously reported interactions. Methods: Ana
To study the association between induction and outcome among two-parous women in uncomplicated pregnancies ≥ 41+3, stratified by first labour delivery mode and conditions present at first delivery. The Swedish Medical Birth Register was used to identify 58,964 uncomplicated singleton pregnancies among women with one previous birth between 1998 and 2014. Women with any registered pregnancy complica
De senaste åren har upphovsrätten fått mycket uppmärksamhet eftersom den digitala utvecklingen och framväxandet av Internet gjort det möjligt att snabbt och utan kvalitetsförlust lagra och överföra stora mängder ljud, bild och text. Denna överföring är inte sällan olovlig och det sker idag omfattande upphovsrättsintrång över Internet. I dessa intrång är det i huvudsak tre olika aktörer som är inblIn recent years, copyright law has been given much attention since the digital development and the emergence of the Internet made it possible to quickly storage and transfer large amounts of audio, images and text without loss of quality. The transfer is often illegal and there is a widespread copyright infringement going on in the Internet environment. In these infringements there are three main
In the last decades Sweden has become a multicultural country. The immigrants come from many different places all-around the world and many have arrived to Sweden, during the 90´s, when they were relatively old. Many of those can not speak Swedish at all or only speak a few words. This demands specific qualifications when it comes to the caregivers, who take care of the elderly. Our purpose with t
