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This article inquires into the role of good faith for the exercise of treaty-based discretionary powers. As the article argues, not only does the principle of good faith form a source of inspiration and an explanatory background to the vast body of law laid down in international treaties. Furthermore, it sets a limit to the application of any treaty rule that confers a discretionary power, whether
Using a self-report questionnaire, the Hospital Anxiety and Depression (HAD) scale, feelings of anxiety and depression were assessed in 133 breast cancer patients referred for adjuvant radiotherapy following surgical treatment. Eighteen patients (14% had scores indicating morbid anxiety. Significant depression was recorded for only 2 patients (1.5% Severe anxiety was recorded for 10 out of 54 mast
Diet and ambient temperature affect animal physiology, survival and reproductive success. However, knowledge of how these environmental factors interact to shape physiological processes and life-history traits of birds and other animals is largely lacking. By exposing adult great tits (Parus major) to two contrasting diets (saturated or unsaturated fatty acids; SFAs and UFAs, respectively) and amb
Objective To describe the frequency of myocardial infarction (MI) prior to the diagnosis of systemic lupus erythematosus (SLE) and within the first 2 years of follow-up. Methods The systemic lupus international collaborating clinics (SLICC) atherosclerosis inception cohort enters patients within 15 months of SLE diagnosis. MIs were reported and attributed on a specialised vascular event form. MIs
The effect of adrenalectomy (Adx) on pancreatic lipase and colipase activities in normal, streptozotocin-induced diabetic, and obese Zucker rats was studied. It was found that Adx induced a rapid decrease in amylase activity, a rapid increase in lipase activity, and a slow increase in colipase activity in normal rats. Twenty days after Adx, the levels of amylase activity were 70% lower than contro
Recent climate warming has altered plant phenology at northern European latitudes, but conclusions regarding the spatial patterns of phenological change and relationships with climate are still challenging as quantitative estimates are strongly diverging. To generate consistent estimates of broad-scale spatially continuous spring plant phen
Many insects have triplets of camera type eyes, called ocelli, whose function remains unclear for most species. Here, we investigate the ocelli of the bumblebee, Bombus terrestris, using reconstructed 3D data from X-ray microtomography scans combined with computational ray-tracing simulations. This method enables us, not only to predict the visual fields of the ocelli, but to explore for the first
Background: Human papillomavirus (HPV) is an established risk factor for oropharyngeal squamous cell carcinoma (OSCC). The aim was to establish cell lines from HPV-positive tonsil carcinomas to be used for treatment development. Methods: Fresh samples from 23 HPV-positive tonsil carcinomas were cultivated in vitro. The established cell line was analyzed for viral characteristics, cell karyotype, T
Research shows that working is positive for people with long-term pain but that work-related support from health professionals is inadequate. One explanation for this inadequacy is that patients and providers differ in terms of perspectives on motivation to work. In this article, we compare factors that 31 patients and 15 general practitioners consider important to promote return to work for peopl
Total offers have become increasingly common in the aircraft industry during recent years. The total offers bring on challenges as well as possibilities for the providers of engine maintenance. The possibilities, increased profitability and efficiency, are depending on how the organisation copes with the challenges. An important challenge is the transfer of risk that occurs in a fixed price situat
Popular Abstract in Swedish Potatis har varit, och är fortfarande ett viktigt baslivsmedel i svensk kosthållning. Det finns många sorter med olika egenskaper vilket bidrar till dess variationsrikedom. Potatisen är en rik källa till stärkelse, kostfibrer samt vitaminer och mineraler, t ex C-vitamin och järn. En invändning mot potatis ur nutritionell synvinkel är att stärkelsen lätt bryts ned av enzDespite decreased consumption potatoes still constitute an important staple in the Swedish diet. An objection to potatoes and potato products from a nutritional point of view is the ease by which the starch is digested and absorbed in the gastrointestinal tract. This results in unfavourably high glycaemic and insulinaemic responses (glycaemic index, GI and insulinaemic index, II, respectively). Su
Introduction: Acute kidney injury (AKI) after cardiac surgery is common and results in increased morbidity and mortality. One possible mechanism for AKI is ischaemia-reperfusion injury caused by the extracorporeal circulation (ECC), resulting in an opening of the mitochondrial permeability transition pore (mPTP) in the kidneys, which can lead to cell injury or cell death. Ciclosporin may block the
Aims: Pulmonary hypertension (PH) patients have high mortality due to right ventricular failure. Predictors of poor prognostic outcome are increased right atrial volume (RAV) and elevated mean right atrial pressure (mRAP). Our aim was to determine whether RAV measured with 2D echocardiography (2DE) and 3D echocardiography (3DE) can detect elevated mRAP in patients evaluated for PH. Methods: Of 85
Metal ion catalyzed autoxidation of of aqueous sulfur dioxide in atmospheric droplets is an important pathway for the total oxidation of sulfur dioxide in the atmosphere and for formation of acid rain. This paper presents a summary of the results obtained for the Mn(II/III) catalyzed oxidation of SO2(aq).
Purpose– The purpose of this paper is to offer a thematic analysis of global sourcing and international purchasing issues in international retail firms.Design/methodology/approach– We review literature that addresses purchasing/sourcing activities of retail firms in foreign markets. We categorize this literature into different themes and analyse how these themes are conceptually or empirically lin
PURPOSE: After DNA damage, checkpoints pathways are activated in the cells to halt the cell cycle, thus ensuring repair or inducing cell death. To better investigate the role of checkpoint kinase 1 (Chk1) in cellular response to different anticancer agents, Chk1 was knocked down in HCT-116 cell line and in its p53-deficient subline by using small interfering RNAs (siRNA).EXPERIMENTAL DESIGN: Chk1
