Filetype
Background: There is an urgent need to improve patient safety in the area of medication treatment among the elderly. The aim of this study was to explore which improvement needs and strengths, relating to medication safety, arise from a multi-professional intervention in primary care and further to describe and follow up on the agreements for change that were established within the intervention. M
The human cytomegalovirus (CMV) immediate early promoter has been extensively used to drive target gene expression in transgenic mammalian cells. DNA methylation of the CMV promoter has been shown to be the reason for a reduced promoter activity and silencing of the target gene. We have established an in vitro model system, in which human brain cancer cells (glioblastoma multiforme, GBM) were tran
Objectives: The paper describes recruitment results and characteristics of the UP-TECH clinical trial sample, including level of care services use, informal caregiver burden and its determinants.Methods: UP-TECH is designed to test innovative care solutions for community-dwelling patients with moderate stage Alzheimer's disease and their caregivers in Italy. Four hundred and fifty patient-caregive
This thesis aims to examine the complex relationship between the realm of politics and media during a ‘terrorist event’ in Turkey by focusing on the politics of fear and the power relations between two. The research uses Critical Discourse Analysis as a primary method to analyse political communication and media coverage of a ‘terrorist attack’ in Turkey. In 6th of September 2015, a military conv
Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
Our aim was to describe a large population-based cohort of diffuse large B-cell lymphoma (DLBCL) during the last decade, evaluating possible improvement in survival and to identify subgroups in need of novel treatment strategies. The study population encompassed all patients diagnosed with DLBCL in Sweden from 2000 through 2010. Altogether 5349 patients were identified. There was no increase in in
Analysing datasets from hunting statistics and human cases of tick-borne encephalitis (TBE), we found a positive correlation between the number of human TBE cases and the number of red fox (Vulpes vulpes). Time lags were also present, indicating that high numbers of red fox in 1 y translated into high numbers of human TBE cases the following y. Results for smaller predators were mixed and inconsis
For many years, the European Union has been aware that its trade with so-called “conflict minerals” has indirectly contributed to conflict and human rights abuses in third countries. In 2014, as a response to this contribution, the European Commission proposed a regulation aiming to control the products containing the minerals that enter the internal market. After three years of complex negotiatio
The situation of unaccompanied asylum-seeking children is nowadays a global issue affecting an important number of children all over the world. Nevertheless, the special needs and vulnerabilities of this group of children have not yet been effectively assessed. In fact, unaccompanied minors constitute the most vulnerable group among all asylum seekers and face human rights’ violations continuously
This study has its starting point in a public debate about disruptive behaviors at public libraries in Sweden. In 2019 a legal bill was proposed, which would make it possible to deny persons who disturb the order at libraries, access to libraries. Representatives from library organizations criticized the proposed bill, stating it is contrary to the current Swedish Library Act. The main purpose wit
The raw material tier in companies’ supply chains can be a hotspot for sustainability issues like deforestation and resulting legal, reputational, financial and operational risks – yet companies’ supply chain management efforts as well as research on sustainable supply chain management still focus on direct suppliers due to poor upstream transparency. With technical progress, remote sensing and sa
This essay examines the use of drones in relation to Just War Theory and Rational choice theory. In order to investigate the use of drones from these perspectives, case studies are used for facilitating the application of these theories. From this analysis, it becomes evident that the use of drones cannot be motivated fully by either of these theories. The results of the study also unearth several
This study deals with two issues. One is the interpretation of reconstructions of Iron Age houses; and the other is whether virtual reality—i.e. 3D modeling—is a useful tool for this interpretation. Physical reconstructions are constrained by both researchers’ and financiers’ interests. These interests sometimes clash, when e.g. return on investment forces a profitable version of a given project,
Optimal management of the commons to ensure sustainability relies on community management. Despite widespread knowledge of this, conventional wisdom is locked into how much the state should regulate the market. Free market ideology, defined as neoliberalism, promotes a culture of extreme competition and individualism which stand in contrast to the needed cultures of participation and inclusion for
Around the world, the treatment of food waste is a major administrative and environmental problem throughout the food supply chain. Beijing, as any other mega city, is facing vast issues of sustainable food waste treatment in addition to efforts for food waste reduction. Presently the majority of Beijing's food waste is treated together with the mixed residual waste in landfills (53%) and inci
To determine the relationship between long-term change in activities of daily living (ADL) and falls in the elderly and to identify characteristics of groups at risk for falls.
Patients with spinal stenosis with concomitant degenerative spondylolisthesis (DS) and predominance of back pain have been shown to have inferior outcome after surgery. Studies comparing outcome according to preoperative pain predominance and treatment received are lacking.
The role of islet GPR40 protein in the pathogenesis of diabetes is unclear. We explored the influence of GPR40 protein levels on hormone secretion in islets from two rat models of spontaneous type 2 diabetes displaying either hyperlipidaemia or hyperglycaemia. GPR40 expression was analysed by confocal microscopy, Western blot and qPCR in islets from preobese Zucker (fa/fa) rats, diabetic Goto-Kaki
