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https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/2025-10/Nyhetsbrev%20fra%CC%8An%20GA%CC%8AS-projektet%20december%202023.pdf - 2026-07-10

Single-cell technologies have transformed our understanding of cellular heterogeneity through multimodal data acquisition. However, robust cell alignment remains a major challenge for data integration and harmonization, including batch correction, label transfer, and multi-omics integration. Many existing methods constrain alignment based on rigid feature-wise distance metrics, limiting their abil

987/5000En omfattande ram för en hållbar renoveringsprocess med en helhetssyn på renovering har utvecklats med beaktande av områdena: teknik, miljö, ekonomi, sociala värden och arkitektur och kulturhistorisk miljö. Ramverket beskriver aktiviteter som ska genomföras i olika steg i processen, samt kartlägger vem som kommer att ansvara för och utföra dessa aktiviteter. Ramverket hänvisar till tillgänA comprehensive framework for a sustainable renovation process with a holistic approach to renovation has been developed, taking into consideration the areas: technology, environment, economy, social values, and architecture and cultural historical environment. The framework describes activities that should be carried out at different stages of the process, as well as charting who will be responsi

Introduction: Case–control analyses have shown BARD1 variants to be associated with up to >2-fold increase in risk of breast cancer, and potentially greater risk of triple negative breast cancer. BARD1 is included in several gene sequencing panels currently marketed for the prediction of risk of cancer, however there are no gene-specific guidelines for the classification of BARD1 variants. We pres

Background: Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor thickness and ulceration. As disruption of the epigenomic landscape is recognized as a widespread feature inherent in tumor development and progression, we aimed to identify novel

Purpose: Most knowledge regarding outcome after adrenal surgery stems from retrospective studies reported by highly specialized centres. The aim of this study was to report a national experience of adrenalectomy with particular attention to predictive factors for postoperative complications, conversion from endoscopic to open surgery and length of hospital stay. Methods: Adrenalectomies reported i

Material resources exploitation and the pressure on natural ecosystems have raised concerns over potential future resource risks and supply failures worldwide. Interest in the concept of Circular Economy has surged in recent years among policy makers and business actors. An increasing amount of literature touches upon the conceptualisation of Circular Economy, the development of ‘circular solution

The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their extracted data matrices, and information about the physical array, the features and reporter molecules. We present a web-based customizable bioinformatics solution called BioArray Software Environment (BASE) for the

A trend, which can be noted in the field of cash handling, is the increase of ATMs that are able to recirculate banknotes. Cash recycling means that notes deposited by one customer are then available for withdrawal by another from the same machine. Cash recycling has both economic advantages and reduces environment impact, as transport to machines for filling and emptying them can be decreased. Wh