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Objectives: To describe and compare the methods of pain management used by elderly individuals with chronic pain and requiring assistance with activities of daily living, depending on whether they live alone, with someone, at home or in special accommodations. Methods: This study comprised 294 people aged 76–100 years, identified as having chronic pain and requiring assistance with activities of
Popular Abstract in Swedish Det mesta av det genetiska materialet i en eukaryot cell finns samlat till kärnan och är organiserat i kromosomer. Varje gång en cell delas kopieras kromosomerna så att de båda resulterande cellerna får ett bibehållet kromosomantal. Den mekanism som styr denna replikeringsprocess förmår dock inte kopiera de yttersta kromosomändarna, vilket resulterar i att dessa blir koTelomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. However, they contain a sequence resembling the consensus binding sequence of the major t
The Multi-plume Aerosol dynamics and Transport (MAT) model has been developed to study the dynamics of the particle size distribution in urban environments. The MAT model uses a novel multi-plume scheme for vertical dispersion and routines of the aerodynamics models AERO3. It treats the processes: emission from a near ground source, dilution with background air, deposition, coagulation and condens
TB PNA FISH is a new fluorescence in situ hybridization (FISH) method using peptide nucleic acid (PNA) probes for differentiation between species of the Mycobacterium tuberculosis complex (MTC) and nontuberculous mycobacteria (NTM) in acid-fast bacillus-positive (AFB+) cultures is described. The test is based on fluorescein-labelled PNA probes that target the rRNA of MTC or NTM species applied to
Popular Abstract in Swedish Variabilitet i ett läkemedels farmakokinetiska (hur ett läkemedel omsätts i kroppen) och farmakodynamiska (vilken effekt ett läkemedel har) egenskaper kan resultera i att olika individer som erhållit samma dos av ett läkemedel får olika effekter av läkemedel. Biverkningar eller utebliven effekt kan innebära allvarliga konsekvenser för den enskilda individen. VariabiliteVariability in pharmacokinetic and pharmacodynamic parameters between individuals can be due to intrinsic and extrinsic factors. In this thesis three different areas regarding sources of variability have been investigated. 1. Formulation properties as an extrinsic source of variability. Lipophilic substances often have poor oral bioavailability and high inter- and intraindividual variability. High
Introduction: Rheumatoid arthritis (RA) is a chronic, inflammatory, and systemic disease with symptoms that limit activities and affect quality of life. RA is associated with an increased risk of developing comorbidities, some of which are also known to be associated with lifestyle habits such as physical activity, diet, smoking, and alcohol. There has been an augmented focus on the implementation
RATIONALE: Improved ventilation strategies have been the mainstay for reducing mortality in acute respiratory distress syndrome. Their unique clinical effectiveness is, however, unmatched by our understanding of the underlying mechanobiology, and their impact on alveolar dynamics and gas exchange remains largely speculative.OBJECTIVES: To assess changes in alveolar dynamics and associated effects
Occupancy of cold habitats by evergreen species requires structural modification of photosynthetic organs for stress resistance and longevity. Such modifications have been described at interspecific level, while intraspecific variation has been underexplored. To identify structural and anatomical traits that may be adaptive in cold environments, we studied intraspecific variability of needles of S
Objectives: To describe the process and outcomes of using a new evidence base to develop scientific guidelines that specify the type and minimum dose of exercise necessary to improve fitness and cardiometabolic health in adults with spinal cord injury (SCI). Setting: International. Methods: Using Appraisal of Guidelines, Research and Evaluation (AGREE) II reporting criteria, steps included (a) det
The electroweak production and subsequent decay of single top quarks in the t-channel is determined by the properties of the Wtb vertex, which can be described by the complex parameters of an effective Lagrangian. An analysis of a triple-differential decay rate in t-channel production is used to simultaneously determine five generalised helicity fractions and phases, as well as the polarisation of
Denna studie undersöker hur slutpriset vid exekutiva försäljningar av småhus och bostadsrätter förhåller sig till bedömt marknadsvärde och till prisbildningen på den frivilliga marknaden. Exekutiva försäljningar som genomförs av Kronofogdemyndigheten(KFM) skiljer sig från frivilliga transaktioner på ett grundläggande sätt: de sker under tvång, med begränsad objektinformation och en reglerad försälThis study examines how transaction prices of forced sales of single-family houses and tenant-owned apartments relate to assessed market value and to prices on the free market. In this study, the term forced sales is used to describe enforcement sales conducted by the Swedish Enforcement Authority (Kronofogdemyndigheten, KFM). Forced sales differ fundamentally from voluntary transactions in that t
Nationella forskarskolan om åldrande och hälsa Established by the SWEAH Board, 23 March 2026 Established by the SWEAH Board, 23 March 2025 Annual Report 2025 Swedish National Graduate School on Ageing and Health Doctoral students and mentors attend a writing retreat during the doctoral student days in Lund, April 2025. Photo: Lill Eriksson sweah.lu.se http://www.sweah.lu.se/ Swedish National Gradu
https://www.sweah.lu.se/sites/sweah.lu.se/files/2026-04/SWEAH%20verksamhetsber%C3%A4ttelse%202025%20final_enGB.pdf - 2026-07-09
Background and Aims: Meckel's diverticulum (MD) may remain silent or be associated with adverse events such as GI bleeding. The main aim of this study was to evaluate indicative small-bowel capsule endoscopy (SBCE) findings, and the secondary aim was to describe clinical presentation in patients with MD. Methods: This retrospective European multicenter study included patients with MD undergoing SB
Methodological considerations in practice-based research: lessons learned from research with a music school in SwedenThis is a presentation of a practice-based research project that has been carried out in collaboration between two course leaders from a music school in Sweden and one researcher between 2022 and 2023. The aim of the research project is to contribute to knowledge about pupil particiMethodological considerations in practice-based research: lessons learned from research with a music school in SwedenThis is a presentation of a practice-based research project that has been carried out in collaboration between two course leaders from a music school in Sweden and one researcher between 2022 and 2023. The aim of the research project is to contribute to knowledge about pupil partici
Background: The diagnosis of monogenic obesity is burdened by frequent variants of uncertain significance (VUS). We describe our real-life approach of variant reassessment over time and we assess whether inconclusive variants are decreasing in monogenic obesity. Methods: We tested for monogenic obesity (genes: LEPR, POMC, ADCY3, PCSK1, CARTPT, SIM1, MRAP2, LEP, NTRK2, BDNF, KSR2, MAGEL2, SH2B1, MC
Purpose: To describe hand function, and investigate adherence to a rehabilitation protocol and factors associated with upper extremity disability in non-surgically treated proximal phalangeal fractures. Material and methods: In a prospective cohort study, 86 patients (58 women, mean age of 49 years) were assessed at cast removal and 6 weeks follow-up. Adherence was registered in a diary. Factors p
Acrolein, as one of the most hazardous aldehydes, can be formed among the carbonyls from the combustion of bio-fuels or mixtures of bio- and conventional fuels. Moreover, acrolein is also an important combustion intermediate in the oxidations of higher unsaturated hydrocarbons. A deep understanding of acrolein combustion chemistry will be useful for the kinetic modeling of higher hydrocarbons and
ABSTRACT: BACKGROUND: Long term endurance training is known to increase peak oxygen uptake () and induce morphological changes of the heart such as increased left ventricular mass (LVM). However, the relationship between and the total heart volume (THV), considering both the left and right ventricular dimensions in both males and females, is not completely described. Therefore, the aim of this stu
PURPOSE:: To describe riboflavin and ultraviolet light (UV) collagen crosslinking as an effective treatment for infectious keratitis. METHODS:: A 25-year-old previously healthy female contact lens user was diagnosed with unilateral severe keratitis with unclear pathogenesis, although the clinical presentation suggested acanthamoeba as the infectious agent. A 4-mm diameter, annular, semi-opaque inf
In its latest assessment report the IPCC stresses the need for carbon dioxide removal (CDR) to counterbalance residual emissions to achieve net zero carbon dioxide or greenhouse gas emissions. There are currently a wide variety of CDR measures available. Their potential and feasibility, however, depends on context specific conditions, as among others biophysical site characteristics, or availabili
