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An experimental system was developed for the rapid measurement of the aspiration/transfer efficiency of aerosol samplers in a wind tunnel. We attempted to measure the aspiration and particle transfer characteristics of two inlets commonly used for sampling airborne Particulate Matter ( PM): the 'Total Suspended Particulate' or TSP inlet, and the louvered 'dichotomous sampler inlet' typically used
Objective. To measure the effect of low-dose systemic glucocorticoid treatment on the adrenal response to adrenocorticotropic hormone (ACTH) in patients with rheumatoid arthritis (RA). Methods. Patients with RA who took part in a randomized double-blind placebo-controlled trial of budesonide (3 mg/day and 9 mg/day) and prednisolone (7.5 mg/day) underwent a short (60-minute) test with injection of
Screening of 29 strains of Neisseria gonorrhoeae revealed that 16/21 serum resistant strains and 0/8 serum sensitive strains bound C4bp. suggesting that C4bp binding to gonococci could contribute to serum resistance. C4bp bound to gonococci retained cofactor (C4b-degrading) function. Using allelic exchange to construct strains with hybrid Por1A/B molecules, we demonstrate that the N-terminal loop
As a consequence of heightened concern for the greenhouse effect, depleting oil reserves and skyrocketing oil prices, renewable fuels, Such as bioethanol, are becoming increasingly important. Cellulosic biomass like wood, agricultural residue and herbaceous material is a huge, cheap natural resource that can be used for ethanol production. Decreasing production costs through technological developm
Nitrogen (N) is often considered to be the major factor limiting tree growth in northern forest ecosystems. An increased N availability, however, increases the demand for other nutrients such as base cations and phosphorous (P) which in turn may change which nutrient is the limiting factor. If P or base cations become limiting, N will start to leach which means a risk of increased eutrophication o
An improved Volume of Fluid (VOF) method is presented which is applicable to high density ratio 3D flows for a large range of bubble Reynolds number (Re). The method is based on the Navier-Stokes equations for incompressible multi-phase flows which are discretized on a Cartesian staggered grid. The multi-grid technique together with the pressure-velocity coupling scheme for multi-phase flows have
Intrauterine growth restriction (IUGR) is a recognized risk factor for neurologic deficits later in life. Abnormal fetal blood flow in the presence of fetal growth retardation helps to distinguish true fetal growth impairment from small but normally grown infants. The present study aimed to investigate the influence of IUGR with abnormal fetal blood flow on retinal optic nerve morphology at 18 y o
Introduction. There are few published guidelines for the management of sexual dysfunctions in men and women, despite the prevalence and lack of attention to these problems. Disorders of sexual function in men include erectile dysfunction, orgasm/ejaculation disorders, priapism, and Peyronie's disease. Aim. To provide evidence-based and expert-opinion consensus guidelines for the clinical managemen
Fondaparinux is a new anticoagulant that interacts with antithrombin III and activated coagulation factor X resulting in an inhibition of the coagulation system. It has been successful in doses of 2.5 mg for thromboprophylaxis as well as in higher therapeutic doses of 5-7.5 mg. No optimal method for monitoring the effects of fondaparinux has been proposed. The aim of the present study was to inves
A simple method is tested for scaling climate-extreme results from high resolution regional climate models (RCMs) to time-periods and emission scenarios for which the RCMs have not been run. The 30 yr mean relationships between indicators of extremes (IoEs) and annual mean daily maximum temperature (T-xa) are investigated. Such relationships from the UK Met Office Hadley Centre RCM HadRM3P, along
Analysis of atrial rhythm is important in the treatment and management of patients with atrial fibrillation. Several algorithms exist for extracting the atrial signal from the electrocardiogram (ECG) in atrial fibrillation, but there are few reports on how well these techniques are able to recover the atrial signal. We assessed and compared three algorithms for extracting the atria] signal from th
BACKGROUND AND AIMS: Orlistat, a lipase inhibitor, strongly inhibits the activities of all gastric/pancreatic lipases except pancreatic phospholipase A(2)in vitro. In clinical use, for obesity treatment, it induces a variable degree of weight loss and steatorrhoéa. The aim of this study was to examine the degree of in vivo inhibition of individual gastric/pancreatic lipases by Orlistat in man, whe
Most of the world's energy generation is based on fossil fuels such as coal and oil, which already today but even more in the future, will cause various problems. One issue is their limited availability, which stands in conflict to the increasing global energy consumption. Another problem is the carbon dioxide generation caused by burning fossil fuels for energy production, and is thought to be on
The human platelet cilostamide- and cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) was rapidly purified approximately 19,000-fold to apparent homogeneity using single step affinity chromatography on the isothiocyanate derivative of cilostamide coupled to aminoethyl agarose. Within 24 h, 30 micrograms of enzyme protein was obtained from 20 ml of packed platelets. Vmax for cAMP and cGMP was 6.1 and
A rapid (6.5 min) and simple one-step magnetic immunoassay (MIA) has been developed for analysis of human urinary albumin in near patient settings. Polyclonal rabbit anti-human albumin was used as a capture antibody and monoclonal mouse anti-human albumin as a detection antibody in a two-site immunometric assay requiring no additional washing procedures. The polyclonal anti-human albumin was conju
Fifteen years after the heavy storm "Vivian", it is still not clear how succession in subalpine forests that were affected by the storm will continue and when regrowing forests will provide effective protection from natural hazards such as avalanches. We used a simulation model to evaluate forest succession, forest structure and the protective effect in subalpine blowdown areas after 50 simulation
Background: Cell death induced by intracellutar glutathione depletion has been reported to be dependent on the presence of trace amounts of extracellular copper ions. Since little is known about the relationship between glutathione depletion and copper homeostasis, we have in the present study further investigated the role of low amounts of copper ions in glutathione depletion. Methods: Glutathion
BACKGROUND AND OBJECTIVES: During the past 10 years several DNA-typing methods have been developed to complement routine serological typing for determination of polymorphisms in the ABO, RH, KEL, JK and FY blood group genes. However, the molecular basis of blood groups can differ widely between ethnic groups. The purpose of this study was to evaluate selected DNA-based methods for phenotype predic
This study investigates the efficacy of tumor radioimmunotargeting with 125I-labeled BR96-biotin monoclonal antibody using a new method, whole-blood immunoadsorption (WBIA), based on direct adsorption of unbound monoclonal antibody (MAb) from blood without preceding separation of plasma. METHODS: Highly tumor-reactive, internalizing, chimeric BR96 MAb of isotype IgG1 binds to a tumor-associated Le
Abstract in French Donnees de base Des études menées en Arique de l'ouest et ailleurs ont suggeree que le vaccin Bacille Calmette-Guerin (BCG) administréà la naissance était bénéfique pour la survie de l'enfant. Cet effet bénéfique proviendrait en partie de l'effet sur la malaria, une hypothèse supportée par des études sur animal. Nous avons investigué si la revaccination avec le BCG à 19 mois rBACKGROUND: Studies in West Africa and elsewhere have suggested that Bacillus Calmette-Guerin (BCG) vaccine given at birth is beneficial for child survival. It is possible that this effect is mediated partly through an effect on malaria, a hypothesis supported by animal studies. We investigated whether revaccination with BCG at 19 months of age reduced morbidity from malaria. METHOD: In the capita
