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A depeptide synthesis was drastically influenced by the reaction temperature, in the range from −30° to 25°C. This article shows the kinetic reasons of this effect. α‐Chymotrypsin was immobilized on celite and used in four different water‐miscible solvents containing small amounts of water‐miscible solvents containing small amounts of water. The reaction studied was the aminolysis of N‐acetyl‐L‐ph

Information relating to errors in evapotranspiration (ET) products, including satellite-derived ET products, is critical to their application but often challenging to obtain, with a limited number of flux towers available for the sufficient validation of measurements. Triple collocation (TC) methods can assess the inherent uncertainties of the above ET products using just three independent variabl

Among the hundreds of known hot Jupiters (HJs), only five have been found to have companions on short-period orbits. Within this rare class of multiple planetary systems, the architecture of WASP-47 is unique, hosting an HJ (planet-b) with both an inner and an outer sub-Neptunian mass companion (-e and -d, respectively) as well as an additional non-transiting, long-period giant (-c). The small per

This study investigates the relationship between changes in the frequency of dwell time delays and passenger flow characteristics and the frequency of railway service during the COVID-19 pandemic. To do so we make use of automatic passenger count data from commuter trains in Southern Sweden. Our findings show that the frequency of dwell time delays decreased under COVID-19 conditions compared to t

This paper presents a statistical combination of searches targeting final states with two top quarks and invisible particles, characterised by the presence of zero, one or two leptons, at least one jet originating from a b-quark and missing transverse momentum. The analyses are searches for phenomena beyond the Standard Model consistent with the direct production of dark matter in pp collisions at

The effect of electron-beam patterning on the water uptake and ionic conductivity of Nafion films using a combination of X-ray photoelectron spectroscopy, quartz crystal microbalance studies, neutron reflectometry, and impedance spectroscopy is reported. The aim is to further characterize the nanoscale patterned Nafion structures recently used as a key element in novel ion-to-electron transducers

Context. The TOI-178 system consists of a nearby, late-K-dwarf with six transiting planets in the super-Earth to mini-Neptune regime, with radii ranging from ∼1.1 to 2.9 R⊕ and orbital periods between 1.9 and 20.7 days. All the planets, but the innermost one, form a chain of Laplace resonances. The fine-tuning and fragility of such orbital configurations ensure that no significant scattering or co

One way of controlling global warming is to substitute fuel driven cars with electric cars. Electric vehicles need to be charged. For maximal efficiency the charging times should be as short as possible. In the US charging stations are classified as Level 1 charging 5–10 miles/h, Level 2 25 miles/h and Fast DCFC stations 150–1000 miles/h. We asked participants to select one of two upgrades of char

Middle-aged adults engaging in unhealthy lifestyle behaviors are at higher risk of chronic diseases. However, little is known about the co-occurrence of these behaviors and their determinants. This cohort study examined the co-occurrence of unhealthy lifestyle behaviors (alcohol consumption, diet, physical inactivity, and smoking) in 30,154 middle-aged adults and their associations with sociodemog

Karst är landskap och karakteristika som är viktiga både ur hydrologisk och geologisk synpunkt och som är utvecklade genom vattnets vittring av oftast karbonathaltiga stenar. Denna uppsats kartlägger världens karstområden, beskriver egenskaper av karst och karsthydrologi och strävar efter att definiera problem och möjligheter med vattenhantering i karstlandskap. Akvifärer i karst skiljer sig i månSummary: Water is, and will in the near future be even more, a key issue for the global development, and for issues concerning equal rigts for all mankind. Water is a necessity and a scarce resource in great parts of the world and it therefore exists a great need for development and management of the world’s waters. With fresh waters being increasingly accentuated for their importance in global de

De senaste 100 åren har den globala medeltemperaturen ökat i genomsnitt 0,74 grader, vilket medför stora effekter för såväl människor som djur och natur. En av de största konsekvenserna till den globala uppvärmningen är att den stigande havsnivån blir allt mer påtaglig världen över. Glaciärer och inlandsisar har börjat smälta allt mer, där avsmältningen medför en global ökning i havsnivån. HavsnivThe rising sea level is becoming more evident around the world as less as well as more developed countries are starting to fully comprehend the consequenses. It is also generally accepted that the sea level rise is accelerated by human-induced global warming. Glaciers and ice sheets are melting more and more, which together with temperature induced thermal expansion of the seas which leads to a gl

We used a high-titer recombinant adeno-associated virus (rAAV) vector to express WT or mutant human alpha -synuclein in the substantia nigra of adult marmosets. The alpha -synuclein protein was expressed in 90-95% of all nigral dopamine neurons and distributed by anterograde transport throughout their axonal and dendritic projections. The transduced neurons developed severe neuronal pathology, inc

Previous studies suggest that the effects of ethanol on carbachol-stimulated I(1,4,5)P3 formation and on the number of mAChRs may be independent of each other. The aim of this work was to further study this hypothesis. Human neuroblastoma SH-SY5Y cells were used as a model system. Acute exposure of the cells to 100 mM ethanol induced a decrease in [3H]N-methylscopolamine ([3H]NMS) binding at 30 se

Background: Despite improvements in therapy regimens over the past decades, overall survival rates for pancreatic and periampullary cancer are poor. Specific cancer registries are set up in various nations to regional differences and to enable larger prospective trials. The aim of this study was to describe the Swedish register, including possibilities to improve diagnostic work-ups, treatment, an

Accurate characterization of large-scale antenna arrays is growing in importance and complexity for the fifth-generation (5G) and beyond systems, as they feature more antenna elements and require increased overall performance. The full 3D patterns of all antenna elements in the array need to be characterized because they are in general different due to construction inaccuracy, coupling, antenna ar

AIM: To assess the results of a urinary diversion in patients who already have a colostomy or simultaneously require a (rectum) colon resection. The diversion is created from the distal part of the transected colon with a simultaneously created new colostomy contra-laterally (if necessary). This procedure is known in our institute as the 'colon shuffle'.MATERIALS AND METHODS: All patients who unde

PURPOSE: Primary cytoreductive surgery (CRS) and peri-operative intraperitoneal chemotherapy (PIC) is the only curative option for patients with colorectal cancer peritoneal carcinomatosis (PC). A significant proportion of patients develop peritoneal recurrence. Outcomes of patients undergoing secondary CRS and PIC for recurrent PC were examined.METHODS: All patients undergoing second procedures w

The effect of molecular weight and temperature on the phase transition and internal structure of poly(N-isopropylacrylamide) brush modified colloidal silica particles was investigated using dynamic light scattering (DLS) and small angle neutron scattering (SANS) between 15 and 45 °C. Dry particle analysis utilising transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FT