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Background: Worldwide, about 1.3 million annual ischaemic strokes (IS) occur in adults aged <50 years. Of these early-onset strokes, up to 50% can be regarded as cryptogenic or associated with conditions with poorly documented causality like patent foramen ovale and coagulopathies. Key hypotheses/aims: (1) Investigate transient triggers and clinical/sub-clinical chronic risk factors associated wit
Microsoft Word - LUSIC Research Workhsop Invitation.docx February 19, 2013 INVITATION Workshop: Social Innovation and Research Date: March 12 Time: 9:00 – 16:00, lunch is included Location: Socialhögskolan – undervisning The Lund University Social Innovation Center (LUSIC), along with our partners at LU Open and Socialhögskolan, would like to
https://www.lu.se/sites/www.lu.se/files/lusic_research_workhsop_invitation.pdf - 2026-07-01
Ultrafast lasers are finding many applications in medicine and biology. Pulses from such systems can be used directly or after non-linear modification. Direct utilisation includes time-resolved fluorescence spectroscopy and imaging. Such studies can be performed for tissue diagnosis in the field of malignant diseases as well as in the cardiovascular sector. Two-photon induced fluorescence provides
This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. Attempts were also made to unravel the mechanism by which VEGF affects neurons and Schwann cells, using a pharmacological approach in c
Background: Lung cancer screening excludes individuals not considered at an increased risk for lung cancer, as predicted by risk models like the Liverpool Lung Project version 3 (LLPv3). In this study, we sought to validate whether plasma glycosaminoglycan profiles (GAGomes) could predict lung cancer independent of LLPv3 and other prespecified comorbidities. Methods: In this retrospective cohort-b
Studies on mantle cell lymphoma (MCL) emphasize that patients with progression of disease (POD) ≤24 months have inferior prognosis compared to patients with later POD. This population-based study assessed the impact of POD on overall survival (OS) by timing of progression and first-line treatment. A total of 1186 MCL patients diagnosed 2006–2018 were identified in the Swedish lymphoma register. PO
Anterior cord herniation is due to a ventral displacement of the spinal cord through a defect in the dura and/or arachnoid.1 Though the condition is rare, some case reports are available.1-3 The neurological symptoms can slowly deteriorate over several years.3 A Brown-Séquard-like syndrome is the most common presenting neurological finding.2,4 Asymptomatic cases may be discovered incidentally.4 Ho
2025 Innovations from Lund University that reached market and other highlights in 2025 2025 Innovations from Lund University that reached market and other highlights in 2025 “Our end-game is enabling research to create global impact — in practise. Building spin-outs and attracting capital is our way of getting there. This brochure features 10 headlines from 2025, showcasing spin-outs on that path.
https://www.innovation.lu.se/sites/innovation.lu.se/files/2026-03/401281-Supplement-LUVentures-2025.pdf - 2026-07-01
It is a hallmark of natural language use that the way we talk about something reflects how it is represented in the mind of our conversation partner. This thesis studies the use and cognitive processing of referring expressions like one in comparison with other expression types in spoken Danish. The cognitive status of referents in other people’s minds can be understood in terms or referential g
There is an ongoing discussion in information retrieval research regarding the merits of subject indexing with controlled vocabularies as opposed to relying on free-text descriptions. Earlier research has compared subject headings with other metadata, such as document titles or tables of contents, to determine the relative value of subject headings as subject access points in an information search
Background: A breeding colony of IL-10 deficient B6.129P2-Il10(tmICgn/J) mice, kept under conventional conditions, developed an inflammatory bowel-like disease (IBD) with rectal prolapse and blood tinged diarrhoea. No clinical signs of disease were observed at the time of arrival to our animal house. These animals were originally planned to serve as a negative control group in an experimental infe
FK506-binding protein-like (FKBPL) has established roles as an anti-tumor protein, with a therapeutic peptide based on this protein, ALM201, shortly entering phase I/II clinical trials. Here, we evaluated FKBPL's prognostic ability in primary breast cancer tissue, represented on tissue microarrays (TMA) from 3277 women recruited into five independent retrospective studies, using immunohistochemist
Sufficient access to financial resources is important in sustaining a business especially in the early phases. First years in business development are very critical since owners learn by doing mistakes in order to get a proof of concept of the business idea. Being aware of this fact, external financial institutions try to avoid taking part in highly risky endeavours. Although there are financial o
Sammanfattning I Sverige råder fri bevisprövning med fri bevisvärdering. Det innebär att inga formella regler uppställs för hur ett bevis ska värderas eller vilka metoder som ska tillämpas av domstolen vid bevisvärderingen. Således är det teoretiskt möjligt att vid en ord mot ord situation finna det ställt utom rimligt tvivel att den tilltalade gjort som åklagaren gör gällande. Trots detta är det Summary In Sweden there is a free sifting of evidence with a free evaluation of evidence. This means that no formal rules are imposed on how evidence should be valued or the methods to be applied by the court at the evaluation of evidence. It is theoretically possible to find it beyond reasonable doubt that the accused made as the prosecutor alleges in a situation where one word stands against ano
Framställningen behandlar domstolens ansvar för utredningen i brottmål och problematiken kring de skillnader som har uppstått mellan regleringen i rättegångsbalken och praxis bland domare. Enligt rättegångsbalken har domstolen tilldelats ett visst ansvar för att målet blir tillräckligt utrett. Bestämmelserna i rättegångsbalken har många år på nacken och härrör från en tid då åklagarväsendet inte vThis essay deals with the court’s responsibility for the investigation in connection to criminal cases, as well as the problems regarding the differences that have appeared between the regulation in rättegångsbalken (the Swedish criminal procedural act) and practice amongst judges. According to rättegångsbalken, the court has, to some degree, a responsibility to assure that the case is properly
Transports, and transport infrastructures enable and deliver vital societal functions in today’s society. At the same time, as sustainability becomes more and more important these sectors fail to enable the rate of change that international and national policies calls for. The electrification of the transport sector is a key driver of the future’s sustainable transport system, and the number of el
Denna rapport beskriver arbetet med att ta fram en landseglare i samarbete med konsultföretaget Semcon. Företaget vill kunna använda produkten på mässor och events, därför ska produkten ska utstråla Semcons värdeord, vilka är ”Responsibility, Credibility, Excellence”. Målet med arbetet är att skapa en landseglare som är mera portabel och enklare att montera jämfört med befintliga på marknaden, menThis report describes the development of a land sailer together with the consulting company Semcon. The company wants to use the product at fairs and internal events, therefore shall the product reflect Semcons core values, which are “Responsibility, Credibility, Excellence”. The aim with the development is to create a land sailer which is more portable and easier to assemble compared to existing
With the trend of decarbonization, the transport sector is exploring possibilities of fossil fuel free solutions. Hydrogen can be a potential fuel for future engine applications. In this work, the concept of H2 HPDI is investigated, where a pilot diesel injection ignites the hydrogen jet. This solution may enable low carbon emission and high energy efficiency. 3D CFD simulation is performed using
Introduction: Shea butter is a kernel derived fat which includes several classes of compounds including lipids like tri- and diacylglycerols as well as unsaponifiable components. Background: Accurate determination of the compound class composition of shea butter is important for industry to quantify the levels of wanted compounds. Size exclusion chromatography (SEC) coupled with refractive index
