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We thank Dr Kurt and colleagues for their comments and interest in our study. High red cell distribution width (RDW) is a new risk factor for cardiovascular disease (CVD), including heart failure, atrial fibrillation and cardiovascular mortality [2-4]. In a recent paper in the Journal of Internal Medicine we reported that low RDW is associated with increased incidence of diabetes [1]. This article

In search for a possible explanation of the phenotypic heterogeneity in selective immunoglobulin (Ig)A deficiency, we studied the IgG2 antibody response to meningococcal polysaccharide A (PSA) in IgA-deficient (IgAd) individuals after vaccination with meningococcal A + C polysaccharide vaccine. Two groups of IgAd individuals, one frequently infected and one clinically apparently healthy, as well a

Column perfusion of mouse pancreatic islets was used to study the ability of amino acids and their methyl esters to influence insulin release and activate islet glutamate dehydrogenase activity. In the absence of L-glutamine, L-serine and the methyl ester of L-phenylalanine, but neither L-phenylalanine nor L-serine methyl ester, stimulate insulin secretion. In the presence of L-glutamine, however,

Rapid and adaptable diagnostic capabilities are of great importance in the face of emerging infectious diseases. In an outbreak, timely establishment of diagnostic routines is crucial to identifying cases and preventing the spread of the disease, especially when faced with high-consequence pathogens. In this article, we describe a multiagency exercise including the rapid deployment and diagnostic

Work rate has a direct impact on the systolic blood pressure (SBP) during aerobic exercise, which may be challenging in the evaluation of the SBP response in athletes reaching high work rates. We aimed to investigate the exercise SBP response in endurance athletes in relation to oxygen uptake (VO2), work rate and to recent reference equations for exercise SBP in the general population. Endurance a

Targeting the androgen receptor (AR) pathway prolongs survival in patients with prostate cancer, but resistance rapidly develops. Understanding this resistance is confounded by a lack of noninvasive means to assess AR activity in vivo. We report intracellular accumulation of a secreted antigen-targeted antibody (SATA) that can be used to characterize disease, guide therapy, and monitor response. A

The COVID-19 pandemic caused universities worldwide, including those in Sweden, to adopt online distance learning as the primary teaching approach. However, there is limited research on how larger environmental changes affect university students’ occupational balance. In this study, 15 university students were interviewed, and their responses were analyzed using qualitative content analysis. The f

High levels of nitrogen (N) deposition might result in a transition from N to phosphorus (P) limitation in high latitude forests. Thiscould have fundamental consequences for forest production, nutrient acquisition and nutrient leaching.I studied a Norway spruce forest in a region of high N deposition in southwest Sweden and added N, P or N+P to force thesystem to N or P limitation. I studied tree

Welcome! INTRODUCTION WEEK 2016 SCHEDULE Congratulations! Not only are you about to start an exciting new chapter of your life at the University of Lund, you’ve also signed up for what might be the most awesome introduction week of all time. Check out the schedule below to see what’s in store! Week 1 Week 2 Monday 22/08: Morning mingle, reception at City Hall and guided tour of Helsingborg. Mornin

https://www.isk.lu.se/en/sites/isk.lu.se.en/files/introductionweek2016schedule.pdf - 2026-07-11

Phosphodiesterase-5 inhibitors are commonly used in pulmonary arterial hypertension but, as suggested by the RESPITE study, phosphodiesterase-5 inhibitor therapy (mono-/combination) does not always have a satisfactory treatment effect. This study aimed to investigate the clinical course of pulmonary arterial hypertension patients not at treatment goal after at least 90 days of treatment with phosp

We present a high-resolution and independently dated multiproxy lake sediment record from the paleolake at Les Echets in southeastern France that displays synchronous changes in independent limnic and terrestrial ecosystem proxies, in concert with millennial-scale climate oscillations during the last glacial period. Distinct lake-level fluctuations, low lake organic productivity, and open, treeles

Anthropogenic elevated atmospheric carbon dioxide (eCO2) increases carbon (C) availability to plants. Whether ecosystems store or release this additional C depends on the balance between net primary production (NPP) and soil respiration, where eCO2-stimulated NPP can be constrained by the provisioning of nutrients by microbial decomposers. Ecosystems gradually become more phosphorus (P)-limited as

Global food security is one of the main concerns of this century. Moreover, the increasing negative impacts of climate change on different sectors including agriculture are further expected to exacerbate these challenges. The main aim of this thesis is to assess the future impacts of climate change on wheat yields in Spain by 2050 and to evaluate the efficiency of early sowing as an adaptation str

Objective: To assess associations and genotype x treatment interactions for melanocortin 4 receptor (MC4R) locus variants and obesity-related traits. Design and Methods: Diabetes prevention program (DPP) participants (N = 3,819, of whom 3,356 were genotyped for baseline and 3,234 for longitudinal analyses) were randomized into intensive lifestyle modification (diet, exercise, weight loss), metform

In the indoor environment there are a number of materials with potential to act as moisture buffers including both building materials and furnishing materials. For daily moisture variations in the indoor air furniture with upholstery can play an important role as moisture buffers. Material properties and calculation models describing the response to moisture variations in the ambient climate for t