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Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2)

Aims: The TTM2-trial is a multi-centre randomised clinical trial where targeted temperature management (TTM) at 33 °C will be compared with normothermia and early treatment of fever (≥37.8 °C) after Out-of-Hospital Cardiac Arrest (OHCA). This paper presents the design and rationale of the TTM2-trial follow-up, where information on secondary and exploratory outcomes will be collected. We also prese

High dose pollen intralymphatic immunotherapy : Two RDBPC trials question the benefit of dose increase

Background: The same dosing schedule, 1000 SQ-U times three, with one-month intervals, have been evaluated in most trials of intralymphatic immunotherapy (ILIT) for the treatment of allergic rhinitis (AR). The present studies evaluated if a dose escalation in ILIT can enhance the clinical and immunological effects, without compromising safety. Methods: Two randomized double-blind placebo-controlle

Wtreatment of copd with long-acting bronchodilators : Association between early and longer-term clinically important improvement

Introduction: This post hoc analysis of the “Early MAXimization of bronchodilation for improving COPD stability” (EMAX) trial investigated whether patients achieving early clinically important improvement (CII) sustained longer-term improvements and lower risk of clinically important deterioration (CID). Methods: Patients were randomized to umeclidinium/vilanterol, umeclidinium, or salmeterol for

Pupil dilation and constriction in the skate Leucoraja erinacea in a simulated natural light field

The skate Leucoraja erinacea has an elaborately shaped pupil, whose characteristics and functions have received little attention. The goal of our study was to investigate the pupil response in relation to natural ambient light intensities. First, we took a recently developed sensory-ecological approach, which gave us a tool for creating a controlled light environment for behavioural work: During a

Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation

Rationale: Galectin-3 (Gal-3) drives fibrosis during chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Effective pharmacological therapies available for ALI are limited; identifying novel concepts in treatment is essential. GB0139 is a Gal-3 inhibitor currently under clinical investigation for the treatment of idiopathic pulmonary fibrosis. We investigate the role

Efficient Modulation of Friction in Ultrasonic Motors Using Functional Fluids

Ultrasonic motors (USMs) have been extensively studied for three decades, due to their attractive features, such as high torque at low speed, simple structure, and precise positioning capability. However, since USMs are driven by the friction force between the rotor and the stator in most cases, they inherently possess the friction loss and the wear of contact materials, which cause their low effi

Risk of incident fractures in individuals hospitalised due to unexplained syncope and orthostatic hypotension

Background Impaired orthostatic blood pressure response and syncope confer a high risk of falls and trauma. The relationship between a history of unexplained syncope and orthostatic hypotension (OH) with subsequent fractures, however, has not been thoroughly examined. In this study, we aimed to investigate the relationship between previous hospital admissions due to unexplained syncope and OH and

Exercise-induced release of cytokines in patients with major depressive disorder.

BACKGROUND: Patients with major depressive disorder (MDD) may display elevated plasma levels of pro-inflammatory substances. Although the underlying mechanisms are unknown, inflammation has been proposed to play a direct role in the generation of depressive symptoms. Skeletal muscle is a potent producer of cytokines, and physical exercise has been suggested to alleviate symptoms of depression. In

Physical activity in people with axial spondyloarthritis and the impact of overall attitudes, barriers, and facilitators : A cross-sectional study

Objective: To study the association between self-reported physical activity level and overall attitudes and barriers to and facilitators of physical activity in people with axial spondyloarthritis (axSpA), and to compare health status and quality of life (QoL) in people with different levels of physical activity. Methods: Four hundred forty-five members of the Danish Patient Association for Axial

Low-cost exercise interventions improve long-term cardiometabolic health independently of a family history of type 2 diabetes : a randomized parallel group trial

INTRODUCTION: To investigate the effect of an exercise prescription and a 1-year supervised exercise intervention, and the modifying effect of the family history of type 2 diabetes (FH), on long-term cardiometabolic health.RESEARCH DESIGN AND METHODS: For this prospective randomized trial, we recruited non-diabetic participants with poor fitness (n=1072, 30-70 years). Participants were randomly as

Airway exposure to urban aerosolized PM2.5 particles induces neuroinflammation and endothelin-mediated contraction of coronary arteries in adult rats

Ambient airborne particles with an aerodynamic diameter of <2.5 µm (PM2.5), which contain particles from combustion processes, are linked to increased risks for cardiovascular and respiratory diseases. In this experimental study, the short-term and long-term physiologic consequences of PM2.5 inhalation were investigated with the focus on inflammatory parameters and vascular tonus. PM2.5 collected

Water penetration in cracked clay brick masonry before and after repointing

This research study investigates the response of clay brick masonry with different crack widths before and after repointing subjected to water spray. In doing so, 3-course masonry prisms containing artificial cracks were exposed to a water spray during 23 hours of testing. Forty-nine cracked 3-course masonry prisms were prepared with a crack width varying between 0.3 mm and 0.9 mm, whereas thirtee

Lunds-universitets-magasin-10-2007

lum_2007_10 LUM Lunds universitets magasin | Nr 10 | 2007 botanfinaL Hur riskfylld är nanotekniken? Svagt intresse för EU-utbyte LUM nr 10 | 2007 LUM nr 10 | 2007 – Hej, vill ni ha julklappar? En tomteklädd student ställer frågan till en grupp nyanlända ira- kiska flyktingar som nyss påbör- jat sina svenskstudier. Det tar lite tid innan det står klart att presen- ten faktiskt är en present, men

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-10-2007.pdf - 2026-06-03

Vol6no2

What makes some persons more prejudiced than others What makes some persons more prejudiced than others? Modeling the role of social dominance, empathy, social desirability, and gender. Martin Bäckström, Fredrik Björklund*, Sven B. Hansson, Dina Bern and Bert Westerlundh Department of Psychology, Lund University Structural equation modeling on questionnaire data showed that different kinds of prej

https://www.psy.lu.se/sites/psy.lu.se/files/vol6no2.pdf - 2026-06-03

The history of neuroscience in autobiography

HON-V10_Anders_Bjorklund.pdf Anders Björklund BORN: Söderhamn, Sweden July 11, 1945 EDUCATION: Lund University, Sweden, Med. Candidate (1966) Lund University, Sweden, MD, PhD (1969) University of Oxford, UK, MS (1989) APPOINTMENTS: Docent of Histology, Lund University, Sweden (1970) Associate Professor of Histology (Lektor), Lund University, Sweden (1973) Professor of Histology, Lund University, S

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/2026-01/the_history_of_neuroscience_in_autobiography.pdf - 2026-06-03

Vbe halsorad inlaga hemsida

VETENSKAP OCH BEPRÖVAD ERFARENHET HÄLSORÅD VETENSKAP OCH BEPRÖVAD ERFARENHET VID SBU | 1 2 | STEN ANTTILA & SUSANNA AXELSSON VETENSKAP OCH BEPRÖVAD ERFARENHET HÄLSORÅD ISBN 978-91-983575-9-2 © VBE-programmet och författarna Grafisk form Johan Laserna Tryckt av Media-Tryck, Lunds universitet, Lund 2020 Förord 9 NILS-ERIC SAHLIN Komplementär och alternativ medicin 17 KJELL ASPLUND Oombedda hälsoråd

https://www.vbe.lu.se/sites/vbe.lu.se/files/vbe_halsorad_inlaga_hemsida.pdf - 2026-06-03

The xx factor 1

T h e x x fa c T o r W om en IN G reat Sciences (W IN G S) Printed by M edia-Tryck, Lund U niversity 2016 N ordic Ecolabel 341903 Lund university isBn 978-91-7623-747-2 9 78 91 76 23 74 72 This book is a journey. a journey Through The hisTory of women aT Lund universiTy, from The pioneering femaLe sTudenT To The groundbreaking femaLe professors of Today. Take an exciTing Trip Through The women in

https://www.wings.lu.se/sites/www.wings.lu.se/files/the_xx_factor_1.pdf - 2026-06-03

Modelling ZnCl2 solutions for quality control in a textile recycling pilot plant

Kvalitetskontrollsmodell för textilåtervinning 2025 infördes en EU-lag som gjorde det obligatoriskt att sortera textilavfall separat. Här presenteras grunden för en modell som relaterar reaktorparametrar till kvalité på återvunnen textilmassa. Textilindustrin omfattade 2024 knappt 2 biljoner USD. Det är en global industri där textilierna ofta designas i USA, produceras i asiatiska länder och slutTextile recycling is highly needed as great amounts of waste are produced every year and most of it is put into landfill or incinerated. This thesis lays the foundations for a quality control system which may be applied for controlling the recycling of cellulosic textiles in an upcoming pilot plant based on ShareTex’s technology. The quality control system was constructed as a mathematical model r

Breathlessness dimensions should be evaluated in relation to the level of exertion : A clinical study

Background/aim: Exertional breathlessness is a dominating symptom in cardiorespiratory disease, limiting exercise capacity. Multidimensional measurement has been proposed to capture breathlessness, but it is unknown whether it is useful to differentiate people with abnormal vs normal exertional breathlessness intensity. Methods: This was a secondary analysis of a randomized controlled trial of out

Therapeutic S100A8/A9 inhibition reduces NADPH oxidase expression, reactive oxygen species production and NLRP3 inflammasome priming in the ischemic myocardium

Oxidative stress and alterations in redox signalling have been implicated in the pathophysiology of myocardial infarction (MI). NADPH oxidase (Nox) is an important source of reactive oxygen species (ROS) in the infarcted myocardium. Alarmin S100A8/A9 amplifies acute myocardial inflammation in MI and has been shown to be a promising therapeutic target to improve cardiac function post-MI. We aimed t