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Publication in nat rev neurosci

The future of stem cell therapies for Parkinson disease Parkinson disease (PD) is a progressive neurodegen- erative disorder that is characterized by relatively focal degeneration of mesencephalic dopamine (mesDA) neurons, the cell bodies of which are located within the substantia nigra pars compacta in the ventral mes- encephalon (VM)1. The associated loss of axonal pro- jections and subsequent d

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nat_rev_neurosci.pdf - 2026-07-20

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Governance issues surrounding technologies are profound. This is best illustrated in the context of climate change that does not only exert severe, pervasive and multifaceted impacts on the environment and on the everyday lives of people around the world, but also further aggravates the tension between law, technology and the public in a broader societal context. As a response to feckless global a

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Lateglacial and Holocene summer sea-surface temperature (SST) variability in the northern North Atlantic was reconstructed based on diatom records from two sediment cores from the North Icelandic shelf. The temperature changes are discussed in relation to palaeoceanographic circulation patterns and past climatic changes. Modern diatom data from surface sediments from around Iceland and Southeast a

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Background and ObjectivesEEG is widely used for prediction of neurologic outcome after cardiac arrest. To better understand the relationship between EEG and neuronal injury, we explored the association between EEG and neurofilament light (NfL) as a marker of neuroaxonal injury, evaluated whether highly malignant EEG patterns are reflected by high NfL levels, and explored the association of EEG bac

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Recreational hunting evokes emotions and could be described as a contested space. The paper presents a study of recreational hunting in Sweden, focusing on accounts and narratives from ethnographic interviews with hunting tourism operators. It discusses how the notion of sustainability permeates and frames moral accounts of hunting practices, game meat, wildlife management, business ethics, animalRecreational hunting evokes emotions and could be described as a contested space. The paper presents a study of recreational hunting in Sweden, focusing on accounts and narratives from ethnographic interviews with hunting tourism operators. It discusses how the notion of sustainability permeates and frames moral accounts of hunting practices, game meat, wildlife management, business ethics, animal

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Objective: To assess the quality of maternal and newborn care (QMNC) in countries of the former Yugoslavia. Method: Women giving birth in a facility in Slovenia, Croatia, Serbia, and Bosnia-Herzegovina between March 1, 2020 and July 1, 2021 answered an online questionnaire including 40 WHO standards-based quality measures. Results: A total of 4817 women were included in the analysis. Significant d

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Background: Like most living organisms, the fruit fly Drosophila melanogaster exhibits strong and diverse behavioural reactions to light. Drosophila is a diurnal animal that displays both short- and long-term responses to light, important for, instance, in avoidance and light wavelength preference, regulation of eclosion, courtship, and activity, and provides an important model organism for unders

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Context: Breathlessness is a cardinal symptom in cardiorespiratory disease and consists of multiple dimensions that can be measured using the instruments Dyspnea-12 (D12) and the Multidimensional Dyspnea Profile (MDP). Objectives: The objective of the study is to determine the minimal clinically important differences (MCIDs) of all D12 and MDP summary and subdomain scores as well as the instrument

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Genom rättens historiska utveckling har åsikterna om hur de psykiskt störda lagöverträdarna ska behandlas gått isär, men särbehandlingstanken har hela tiden funnits med. Utgångspunkten i den svenska rättsordningen är att psykiskt störda lagöverträdare som begår brott ska dömas till ansvar för det. För de som räknas som allvarligt psykiskt störda ges viss särbehandling vid påföljdsvalet. En allvarlThroughout the development of Law, opinions regarding the treatment of mentally disturbed offenders have varied. The idea that they should be treated differently has however always existed. The starting point of the Swedish legal system is that mentally disturbed offenders should be sentenced. Those who are seriously mentally disturbed can however be treated differently in sentencing. A serious me

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Increasing CO₂ emission is considered as the main reason for global warming in the world. One of the reasons for producing CO₂ is using of fossil-based materials in the construction projects. This study intends to assess the using bio-based materials instead of fossil-based materials for the thermal insulation layer of the external walls and roofs. Another focus of this project is using green conc

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Research on InterStellar Objects (ISOs) has been done for several decades, however, the first observed ISO in the Solar system was only recently discovered in 2017. It was named 1I/'Oumuamua and was only passing though the Solar system, but this may not be the case for all objects of its kind. For instance, one could gain a bound orbit around the Sun if the right amount of nudge is acquired wh

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Initiation of construction of apartments has increased by 26% from 2014 to 2015 in Sweden. This has meant more building permits to treat. Several tasks done by a building inspector has been identified through active observation of the building permit department in Helsingborg. Some of the tasks are review of cases, technical consultation, and visits at building places, final consultation, supervis

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As a primary driver of climate change, energy systems are often affected by the type of “self-perpetuation and lock-in” that characterize so-called ‘wicked problems’. Although it has a relatively clean energy system, Canada still has provinces (e.g. Alberta, Saskatchewan) that possess carbon-intensive power grids, and provinces that have experienced minimal renewable energy development other tha

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Context. To use the data in the future Gaia catalogue it is important to have accurate estimates of the statistical uncertainties and correlations of the errors in the astrometric data given in the catalogue. Aims. In a previous paper we derived a mathematical model for computing the covariances of the astrometric data based on series expansions and a simplified attitude description. The aim of th

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Former research indicates that the crack width close to the bar can be a better indicator for the risk for reinforcement corrosion than, as current concrete codes impose, the crack width at the concrete surface. In this paper a finite-element model is used to increase the understanding of how the crack width varies at different levels from the reinforcement and how different mechanisms control thi

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Background  Gastrostomy placement in children is one of the most frequently performed pediatric surgical procedures and laparoscopic-assisted gastrostomy (LAG) is the preferred technique. Wound infection after LAG has become a significant concern due to the emergence of antibiotic resistance. The aim of this study was to describe the frequency of wound infection after LAG in children younger than

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The agricultural sector is thought to be responsible for around 30% of the anthropogenic climate change and it is well established that high meat consumption has a tremendous impact on the environment. Rapeseed is mainly used for production of vegetable oil, but press cake has high protein content with the potential for incorporation into new plant protein-based foods. Protein was recovered from p

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The functional properties of Andean grain starches of two species, amaranth (Amaranthus caudatus) and canihua (Chenopodium pallidicaule), three cultivars each, were studied. The study focused on chemical composition, pasting properties, thermal properties, water solubility index (WSI), swelling power (SP), and granule morphology. All amaranth starches were waxy starches, with amylose content l

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Objective To update the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) in a defined geographical area of southern Sweden.Methods The study area comprised 14 municipalities with a combined adult population (≥18 years) of 623 872 in 2019. All cases diagnosed with AAV in 1997–2019 in the study area were included in the estimate of incidence. Diagnosis of AAV was veri