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All cells of the musculoskeletal system possess transmembrane syndecan proteoglycans, notably syndecan-4. In fibroblasts it regulates integrin-mediated adhesion to the extracellular matrix. Syndecan-4 null mice have a complex wound repair phenotype while their fibroblasts have reduced focal adhesions and matrix contraction abilities. Signalling through syndecan-4 core protein to the actin cytoskel

Nature-based solutions (NBS) can help tackle climate change and advance urban sustainability by using nature to deliver social, ecological and economic benefits. However, their success largely depend on implementation for which several barriers exist. For NBS to be meaningful in terms of delivering positive impacts in cities, we need better understanding of how implementation is embedded in NBS fr

Monoclonal antibody solutions are set to become a major therapeutic tool in the years to come, capable of targeting various diseases by clever design of their antigen binding site. However, the formulation of stable solutions suitable for patient self-administration typically presents challenges, as a result of the increase in viscosity that often occurs at high concentrations. Here, we establish

The conversion of biomass to transportation fuels and value-added chemicals is a promising method to reduce the reliance on fossil fuels. Mo-based catalysts have been shown to be highly active in the hydrodeoxygenation of biomass-derived phenolic compounds. The catalyst active phase, surface species, and the effect of adding additional metals are not comprehensively understood. Here we compare the

Within insect communities, the population ecology of organisms representing higher trophic levels, for example, hymenopterous parasitoids, may be influenced by the structure of their insect hosts. Using microsatellite markers and ecological data, we investigated the population structure of the specialist braconid wasp parasitoid, Lysiphlebus hirticornis Mackauer attacking Metopeurum fuscoviride, a

AIM: Injections administered by patients are one of the mainstays of diabetes management. Proper injection technique is vital to avoiding intramuscular injections, ensuring appropriate delivery to the subcutaneous tissues and avoiding common complications such as lipohypertrophy. Yet few formal guidelines have been published summarizing all that is known about best practice. We propose new injecti

Purpose: An unprecedented scale of human migration has lead humanitarians to view camps as long-term settlements rather than temporary holding facilities. The purpose of this paper is to increase the understanding of and identify challenges with this proposed new approach to camp design. Design/methodology/approach: Based on the camp design literature, the authors developed an interview guide and

Active design is an expression that has been used fore some years now. This paper will present a case study from an excavation of two cavern constructions (80m long x 16m wide x 12m high) and access tunnels in a Bryozoan limestone in southern Sweden. By using various geophysical survey methods like for instance resistivity soundings, in combination with core drilling and geophysical well logs a ge

The ecosystem services approach can inform decision-making by accounting for both short- and long-term benefits from different land use options. Here we used the InVEST toolkit to quantify and map key ecosystem services at the largest publicly-owned agro-silvo-pastoral farmstead in Portugal–a site representative for the montado landscape. We analyzed how Provisioning (cork production) and Regulati

Caroline Eliasson Avfall – en av framtidens viktigaste resurser Avfallshanteringen har i både Sverige och EU genomgått stora förändringar de senaste åren. Ny lagstiftning och nya styrmedel har implementerats och gett gott resultat genom att minska mängden avfall som deponeras. Nästa utmaning är att kunna utnyttja materialet i avfallet mer än en gång. För det krävs nya strategier. AvfallshanterThe thesis consists of a description of the waste management in Sweden today, related to a case study at IKEA’s warehouses in Älmhult. Waste is globally one of the most important environmental challenges. Waste management in Sweden has developed a lot during the past years and is now standing in front of the next big challenge: to reach higher up in the waste hierarchy. By studying the academic li

Streptomyces is the largest genus in the phylum Actinobacteria, known for their complex life cycle and secondary metabolite production. The model bacterium Streptomyces coelicolor grows _lamentously by tip extension and hyphal branching. The hyphal tip is highly organised, with various structural proteins forming a large assembly termed the polarisome. An essential protein, DivIVA, localises to th

The construction industry plays a vital role in societal development but faces increasing demands to reduce its environmental impact, particularly the high carbon footprint associated with concrete production. Among the most widely used structural elements in buildings are concrete slabs, which are fundamental for load transfer and spatial integrity. However, these elements could be overdesigned,

The city of Chennai evolved around the river, Cooum. The river supports irrigation to agricultural fields in the north and supplies water to the city of Chennai. It also acts as a major flood carrier for the city. Before the 1960s, the river was clean and used for activities such as bathing, boating and fishing. During the colonial rule, the city was initially planned to sustain a much lesser popu

The Swedish Government announced that coming fall of 2022 the school curriculum will change significantly in its approach to sexual education to include subjects such as consent, sexuality and relationships, as well as critical conversations about representation of sex in different forms of media, including pornography. To combat children's exposure to porn, child rights activists are calling

Background: Increasing cost effectiveness and productivity are key issues for Haldex. These improvements are obtained through Haldex Way, the overall management and process improvement framework. Haldex Way‟s deployment, progression and assessment are based on a five level Tier model, the concern with Haldex Way Tier model is that its evolution has been inconsistent and the Tier levels have been a

BACKGROUND: Drug delivery systems that are able to control the release of bioactive molecules and designed to carry drugs to target sites are of particular interest for tissue therapy. Moreover, systems comprising materials that can respond to environmental stimuli and promote self-assembly and higher order supramolecular organization are especially useful in the biomedical field. Objetive: This r

Jordens havsnivå förändras ständigt och dessa förändringar kan ha olika orsaker: i ett längre geologiskt tidsperspektiv är det processer i jordens inre som påverkar havsnivån, men i ett kortare perspektiv spelar till exempel tillväxten och avsmältningen av inlandsisar stor roll. Under kvartärtiden har den sistnämnda processen varit den dominerande vad gäller att påverka havsnivåerna: vid istider hResults from an investigation of relative sea-level changes from c. 11,000 cal. yr BP to the present in the Tasiusaq area, Inner Bredefjord, southwest Greenland, are presented in this thesis. Isolation sequences from two small lakes have been identified using stratigraphic analyses, XRF-scanning, loss on ignition and macrofossil analyses. Macrofossil and bulk samples have been dated in order to e

Syftet med detta examensarbete har varit att utarbeta ett konkret förslag för logistisk implementering av industriella biometananläggningar i sydvästra Sverige. Genom att utnyttja restflöden från jord- och skogsbruk – såsom halm, GROT (grenar och toppar) samt såg- och kutterspån – undersöks möjligheten att ersätta fossil naturgas i det sydvästsvenska gasnätet med 100% förnybar biometan (uppgraderaThis thesis aims to develop a concrete proposal for the logistical implementation of industrial biomethane plants in southwestern Sweden. By utilizing residual biomass from agriculture and forestry, such as straw, forest residues (GROT), and sawdust, the study explores the feasibility of replacing fossil natural gas in the regional gas grid with 100% renewable biomethane (upgraded biogas). A comp

This thesis examines the temporary use and development of Botulfsplatsen, a future central public square in Lund, Sweden. Previously a node for city buses, the municipality decided to repurpose the site for interim use as a way to test and activate the square prior to its permanent reconstruction. Drawing on theories of placemaking, temporary use, and relational geography, the study addresses two