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The emergence of catalysis in a noncatalytic protein scaffold is a rare, unexplored event. Chalcone isomerase (CHI), a key enzyme in plant flavonoid biosynthesis, is presumed to have evolved from a nonenzymatic ancestor related to the widely distributed fatty-acid binding proteins (FAPs) and a plant protein family with no isomerase activity (CHILs). Ancestral inference supported the evolution of C

In development, epigenetic mechanisms such as DNA methylation have been suggested to provide a cellular memory to maintain multipotency but also stabilize cell fate decisions and direct lineage restriction. In this study, we set out to characterize changes in DNA methylation and gene expression during granulopoiesis using 4 distinct cell populations ranging from the oligopotent common myeloid prog

The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for combatting bacterial infection. Complement permits the efficient labelling of bacteria with opsonins, supports phagocytosis, and facilitates phag

Many antibiotics inhibit bacterial growth by binding to the ribosome and interfering with protein biosynthesis. Macrolides represent one of the most successful classes of ribosome-targeting antibiotics. The main clinically relevant mechanism of resistance to macrolides is dimethylation of the 23S rRNA nucleotide A2058, located in the drug-binding site, a reaction catalyzed by Erm-type rRNA methylt

Though the existence of cultural ecosystem services is dependent on people's activities and experiences, these services are still commonly assessed using top–down approaches. In this study, appraisal theory and research into human responses to natural environments formed the basis of a systematic multilevel investigation of appraisals of created wetland areas. The aim was to explore how appraisals

We examine the long-term effects of a series of Swedish towns founded by the Crown during the early modern period. Their advantage over rural parishes consisted in having monopoly rights to trade with the local hinterland. Since the optimum sites were occupied by medieval towns, the Crown could only aim for second-rate locations. Using difference-in-difference combined with Propensity Score Matchi

This article contributes to scholarly discussions about sanctuary enactments. We analyse transversal sanctuary enactments, i.e. when migrants in search of protection are provided with basic welfare and an opportunity to remain, in contestation of the state’s migration politics. The study draws on empirical data collected through a transdisciplinary research initiative in Sweden, the Asylum Commiss

Human carbonic anhydrase II catalyzes the reversible reaction of carbon dioxide and water to form bicarbonate and a proton. His64-mediated proton shuttling between the active site and the bulk solvent is rate limiting. Here we investigate the protonation behavior of His64 as well as its structural and dynamic features in a pH dependent way. We derive two pK a values for His64, 6.25 and 7.60, that

The Forward Physics Facility (FPF) is a proposal to create a cavern with the space and infrastructure to support a suite of far-forward experiments at the Large Hadron Collider during the High Luminosity era. Located along the beam collision axis and shielded from the interaction point by at least 100 m of concrete and rock, the FPF will house experiments that will detect particles outside the acc

Access to reliable electricity is essential for delivering safe and effective healthcare. However, many rural healthcare facilities in Mozambique operate without power or experience frequent and prolonged outages. This thesis investigates the potential of repurposed end-of-life (EoL) lithium-ion batteries (LiBs) as an energy storage solution in such contexts. Based on fieldwork in local settings

Technological advancements cause it to be more common for managers and subordinates to work together from different geographical locations. It is associated with challenges, which virtual leadership is supposed to support in overcoming. As the leader is central in studies on virtual leadership, this qualitative study takes a different perspective and has as its purpose to understand how leadership

This qualitative study examines the dominant fertility discourse in Finnish media in 2019, when the total fertility rate dropped to an all-time low level, spurring media debate and political attention. The study analyses the representations and framings of fertility, and the underlying norms, assumptions, power-structures and silences in the dominant discourse using discourse analytical tools, mor

Bismuth (Bi) induced c(4 x 4) surface structure of the GaAs(1 0 0) substrate, i.e., the GaAs(1 0 0)c(4 x 4)-Bi surface has been studied with synchrotron-radiation photoelectron spectroscopy and ab initio calculations. The surface was prepared by combining molecular beam epitaxy and in situ electron diffraction methods, and then the sample was transferred to a photoemission chamber without breaking

The transport behavior of lambda-DNA (48 kbp) in fused silica nanoslits is investigated upon application of electrical fields of different strengths. The slit dimensions are 20 nm in height, 3 microm in width, and 500 microm in length. With fields of 30 kV/m or below, the molecules move fluently through the slits, while at higher electrical fields, the DNA molecules move intermittently, resulting

Policy for green growth and system innovation 1Advanced Programme for a National Innovation System POLICY FOR GREEN GROWTH AND SYSTEM INNOVATION CONTEXT The Nordic countries are among the forerunners in the transition to sustainable and prosperous societies, however, the severity of global warming and other grand challenges such as the biodiver- sity crisis makes it essential to maintain and stren

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2021-05/Policy-for-green-growth-and-system-innovation_0.pdf - 2026-05-07

1 KURSUTVÄRDERING FÖR KURS 2 – KURSOMGÅNG: VT17 – HT17 & HT17 – VT18 1) Kursvärderingsresultat Delkursvärderingar 2:1 (Biologisk psykologi): VT17 fick 2:1 helhetsbetyg 4,5 (svarsfrekvens 80 %) och HT17 4,7 (svarsfrekvens 76 %). Inga moment underkändes. Högst värde VT17 fick Genomtänkt struktur (4,6), Kursgruppsklimat (4,6) och Hjärnmodellsövningen (4,5). Högst värde HT17 fick Examinationernas rele

https://www.psy.lu.se/sites/psy.lu.se/files/psp-bil_7-2018_p5b_2_psp-2-hel-kursutv.pdf - 2026-05-07

Thesis Title Master’s Dissertation Engineering Acoustics STINA WARGERT A NEW APPROACH FOR DETECTING STRONG REFLECTIONS IN ROOMS DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF ENGINEERING ACOUSTICS ISRN LUTVDG/TVBA--14/5045--SE (1-73) | ISSN 0281-8477 MASTER’S DISSERTATION Supervisors: JONAS BRUNSKOG, Assoc. Prof. and CHEOL-HO JEONG, Assoc. Prof., Dept. of Electrical Engineering - Acoustic Technol

https://www.akustik.lth.se/fileadmin/tekniskakustik/publications/tvba5000/webTVBA5045.pdf - 2026-05-04

1. Universitetsinformation i SoleMove | Studentwebben LTH Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i vå

https://www.student.lth.se/internationella-moejligheter/utbytesstudier/ansoekningsguide/1-universitetsinformation-i-solemove/ - 2026-05-04

Zuzana Zalanova: A Generation that Respects Human Rights - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law - Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outr

https://rwi.lu.se/news/zuzana-zalanova-democratization/ - 2026-05-04