Filetype
To find out whether IgG genes are involved in atopy we studied 26 of 101 laboratory technicians who had developed laboratory animal allergy (LAA). The genes for the constant region of the heavy chains of IgG subclasses were analyzed by serum Gm allotypes, representing products on allelic level of the IGHCG1, IGHCG2 and IGHCG3 on chromosome 14q32. There was a significantly increased frequency of th
Background: Impaired trophoblast invasion is suggested as the main cause of reduced placental perfusion, which results in fetal growth restriction and preeclampsia. Immunological response against the invading tissue has been given as the explanation. Preeclampsia frequently recurs during the next pregnancy. Doppler ultrasound can predict increased vascular impedance in the uteroplacental circulati
According to direct perception theory (DPT) people understand each other’s minds by way of perceiving each other’s behavioral engagements in the world. I argue that DPT admits of two interpretations. One interpretation is found in Searle’s social ontology. The other interpretation departs from an enactivist account of social cognition. Both can be employed to make sense of what it is to perceive o
This thesis consists of two parts, applying concepts from automatic control to different application areas.The first part of this thesis concerns the development of an optimization-based algorithm, determining the size of insulin and glucose doses for patients suffering from Diabetes Mellitus and treated with multiple insulin injections. Diabetes Mellitus is a chronic disease characterized by elev
The translational GTPases hydrolyze GTP on the ribosome at several stages of the protein synthesis cycle. Because of the strong conservation of their catalytic center, these enzymes are expected to operate through a universal hydrolysis mechanism, in which a critical histidine residue together with the sarcin-ricin loop of the large ribosomal subunit is necessary for GTPase activation. Here we exa
»Music to me is… my work. I've landed in the best job in the world, where a core task is to discover new music, to learn its internal logic and aesthetics, who created it, and why. I'm a music researcher and have just returned from the island of Java in Indonesia with my research partner and husband Nils, where we've been visiting experimental musicians in Yogyakarta – artists we've now followed f
Background. CRIM1 is a plasma membrane bound protein containing six cysteine-rich repeats (CRR). Through these, CRIM1 has been shown to interact with a subgroup of the TGF-β superfamily, the bone morphogenic proteins (BMP) isoforms 2, 4 and 7. The probable action is to modulate the signalling properties of these factors. CRIM1 has also been shown to regulate the release of VEGFA by podocytes durin
Aviation in Europe has undergone an enormous change from national rulemaking to common European rulemaking. Behind this change is the European Union’s decision to delegate some policy implementation functions to decentralised agencies. The European Union Aviation Safety Agency (EASA) is one of these EU agencies and has specific authorisation to implement decisions that directly impact individuals,
This research report was carried out in collaboration with Qlik AB and aimed to identify what aspects are needed from a software platform in order for developers to want to use them. It also aimed to identify how well the software platform Qlik Core had implemented these aspects. The research used online questionnaires, interviews and data analysis using Qlik Sense. The research compared how diffe
Rätten till en rättvis rättegång är inkluderad i flera större internationella konventioner för mänskliga rättigheter, bland annat i ICCPR och UDHR. Rätten till ett försvar, oskyldighetspresumtionen, rätten att höras av en självständig, objektiv och kompetent domstol och rätten att inte godtyckligt bli berövad sin frihet är alla innefattade i rätten till en rättvis rättegång. ICCPR och CRC föreskri
Background: Between smokers matched for daily tobacco consumption there are marked variations of the cardiovascular risk. This follow up of the population based cohort “Men born in 1914” from Malmö, Sweden, explored whether this is accounted for by the levels of carbon monoxide (CO). Methods: Three hundred and sixty-five men without history of cardiovascular disease (CVD) were followed over 27
Objective: To evaluate how often low 5-min Apgar scores (AS(5-min)) at term are associated with asphyxia. Study design: A cohort- and case-control study, including all 183 term infants with AS(5-min) below 7 born at Lund University Hospital during 1993-2002, antepartum deaths excluded. The control group included 183 randomly selected term newborns with AS(5-min) 9-10. Cardiotocography (CTG) traces
Microbial eukaryotes (protists) have major functional roles in aquatic ecosystems, including the biogeochemical cycling of elements as well as occupying various roles in the food web. Despite their importance for ecosystem function, the factors that drive diversification in protists are not known. Here, we aimed to identify the factors that drive differentiation and, subsequently, speciation in a
We contribute to the literature on the assessment of innovation systems by relating the amount of inputs available to the system and its performance through the concept of returns to scale (increasing, constant or decreasing). We study to what extent the size or scale of innovation systems relates to their performance, which is estimated through frontier Data Envelopment Analysis-TOPSIS methods, w
Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate with preeclampsia in the maternal genome at ZNF831/20q13 and FTO/16q12. These are previously established variants for blood pressure (BP) and the FTO variant has also been associat
