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Background
There is increased pressure on the supply chain to drive improvements to support overall business performance. Previously, the overall supply chain performance has lacked the right set of performance measures and has not been monitored, with fragmented improvement projects as the result.
To address this, a supply chain Balanced Scorecard has been devised for global u
The Chinese economy has been growing with a pace and duration that the world has never seen before. Since 1978, the country has been facing a constant economic growth for more than 30 years. One of the pillars of the economy is the automotive industry; an interesting mixture of Joint Ventures and independent companies. The competition is cut throat and has even been more intense after the China’s
Computer programs are excluded subject matter ''as such'' under the EPC. However, once ''technical character'' can be established in a software invention, and it fulfills all the requirements for patentability - being an invention, which is novel, has inventive step and is industrially applicable - software is very much patentable. The technical character requiremen
Background About 30% of cases of chronic lymphocytic leukaemia (CLL) carry quasi-identical B-cell receptor immunoglobulins and can be assigned to distinct stereotyped subsets. Although preliminary evidence suggests that B-cell receptor immunoglobulin stereotypy is relevant from a clinical viewpoint, this aspect has never been explored in a systematic manner or in a cohort of adequate size that wou
Det är viktigt att det i ett land finns rättssäkerhetsgarantier. För svensk del är Europeiska konventionen angående skydd för de mänskliga rättigheterna och de grundläggande friheterna en väldigt viktig utgångspunkt. I min framställning har jag studerat vilka krav konventionen ställer på rätten till en domstolsprövning och en rättssäker process, art 6 i Europakonventionen. Med dessa krav i bakhuvuLegal certainty is important in every country. For the Swedish part the European Convention on Human Rights and Fundamental Freedoms is a very important starting point and framework. In my presentation, I have studied the requirements that the Convention imposes on the access to court and the entitlement to a fair and public hearing, art 6 of the Convention. With these requirements in mind, I look
In the Church of Sweden every person who is baptized is welcome to join in the Eucharist. However, in recent years three motions have been submitted to the General Synod of the Church of Sweden suggesting that the Eucharist be opened up to the unbaptized as well. I find this to be an interesting issue because it is a provocative one: it challenges a tradition that goes back to the earliest days of
Aims/hypothesis: Low birthweight (LBW) is associated with younger age, less obesity and more hypertension among people recently diagnosed with type 2 diabetes, as well as increased cardiovascular morbidity and mortality risk. It is not known whether LBW is associated with an increased risk of incident chronic kidney disease (CKD) among people with a type 2 diabetes diagnosis. Methods: Original mid
The main purpose of this study was to examine the relationship between adult attachment, denoted as mental representations of childhood experiences, and social relations. A secondary purpose was to examine the impact of prematurity on attachment and social relations in adult age. The study is part of a larger longitudinal study carried out by professor Karin Stjernqvist and Anne-Li Hallin, candida
We studied the effects of high-dose methylprednisolone on the survival of intrastriatal neural xenografts and the host responses against them. Dissociated mesencephalic tissue from inbred mouse (CBA-strain) embryos was transplanted to the intact striatum of adult Sprague-Dawley rats. The rats received either daily injections of methylprednisolone (30 mg/kg), or cyclosporin A (10 mg/kg), or no immu
A 27-47-GHz differential cascode power amplifier for millimeter-wave 5G new radio applications is presented. The PA is a three-stage design using inductively coupled impedance transformers with 31-dB nominal power gain. A device periphery ratio of 1:2:6 is adopted for predriver, driver, and final stage, respectively. A gain equalization technique was used in the interstage transformers to obtain t
Background: Current equations for estimated glomerular filtration rate (eGFR) that use serum creatinine or cystatin C incorporate age, sex, and race to estimate measured GFR. However, race in eGFR equations is a social and not a biologic construct.Methods: We developed new eGFR equations without race using data from two development data sets: 10 studies (8254 participants, 31.5% Black) for serum c
Background: Infertile men with non-obstructive azoospermia (NOA) have impaired spermatogenesis. Dilated and un-dilated atrophic seminiferous tubules are often present in the testes of these patients, with the highest likelihood of active spermatogenesis in the dilated tubules. Little is known about the un-dilated tubules, which in NOA patients constitute the majority. To advance therapeutic strate
Over the past two decades there has been increased interest in orphan drug development for rare diseases. However, hurdles to clinical trial design for these disorders remain. This phase 1a/1b study addressed several challenges, while evaluating the safety and tolerability of the novel oral molecule KL1333 in healthy volunteers and subjects with primary mitochondrial disease.KL1333 aims to normali
This study investigated the tolerance and safety of pasteurized donor human milk (PDHM) given either alone or together with commercially-used supplements in a porcine model of premature infants. A porcine model, mimicking human neonates at 30-32 weeks of gestational age, was used. The 7-day experiment was performed on 20 piglets. After birth, the piglets were infused with porcine immunoglobulins v
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Studies of the immunopathogenesis in JIA has mainly focused on the adaptive immune system, while less is known of the role of the monocytes. JIA is considered a chronic disease, although only about 50% of participants in long-term follow-up studies have active disease as adults. The treatment arsenal for JIA has
Microbicides in the leather industries are employed to avoid the biodeterioration of the hides by microorganisms. This problem may lead to harmful characteristics to the end product such as stains, roughness and decrease mechanical properties of leather. Therefore, microbicides like the 2-(thiocyanomethylthio) benzothiazole (TMCTB) are applied in distinct steps of the tanning process as alternativ
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer with a 5-year survival rate of less than 1-2%. Early onset pancreatic cancer (EOPC), i.e. patients below 50 years of age, is infrequently described. The present study aimed to determine the epidemiology, demographic incidence and prognosis of EOPC and to identify the characteristics that might distin
The history of rail transport can offer valuable insights for future energy transitions due to its importance in promoting clean mobility. There is a complex interplay between the evolution of the railway network, fuel consumption, efficiency, energy service, and CO2 emissions that requires further exploration. We developed a dataset that covers energy use in all stages of rail transportation, as
Excessive work among adolescents may compromise educational development. Without home appliances, household work can take over 50 h a week and an additional 30 h when an infant is present. School-aged girls are often tasked with doing laundry, which is time-consuming and inflexible without a washing machine. We determined the association between washing machine ownership and school attendance amon
