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This thesis is a combined conceptual study and preliminary design of two study options for a future tramway line between Trädgårdsgatan and Hälsovägen in Helsingborg. This line is of great interest since it’s centrally located and regarded as a problematic stretch of narrow streets, heavy traffic and steep gradients. In addition, a local tramway line in Helsingborg is regarded as a priority projec
Thomas Quick erkände under 1990-talet ett 30-tal mord som han påstod att han begått i Sverige, Norge, Danmark, och Finland under åren 1964-1993. Han dömdes för åtta av dem. 18 år senare, i december 2008, tar han tillbaka alla sina erkännanden av mord och begär resning för samtliga fällande domar. Detta har hittills resulterat i tre frikännande domar samt två positiva resningsbeslut. Pelle Svensson
Association for computer aided genealogy research of Sweden(DIS) is investigating the possibility of a nationwide genealogical database (RGD) of Sweden's historical population. The finished database should contain basic information about individuals' names, birth, marriage, death, and individuals' relationships such as father, mother, husband/wife and children. This will make up a kind
Den 1 oktober 2009 trädde en de nya Takeover-reglerna i kraft. Den största nyheten i de nya reglerna var den kraftigt minskade möjligheten att erbjuda röststarka aktier ett högre pris än röstsvaga aktier i ett offentligt uppköpserbjudande. Detta är en skärpning av den aktiemarknadsrättsliga likhetsprincipen och avsikten var att tillförsäkra minoritetsägare en större del av uppköpspremien. UppsatseThe 1 October 2009 new Takeover Rules entered into force. The most material change of the new rules was that they decreased the possibility to offer multiple voting shares a higher price than ordinary shares. This is a strengthening of the legal principle of equality as applied at the Nasdaq OMX Stockholm stock market. The intention was to ensure that minority shareholders got a greater share of t
Background Type 2 (T2) high asthma is recognised as a heterogenous entity consisting of several endotypes; however, the prevalence and distribution of the T2 biomarkers in the general asthma population, across asthma severity, and across compartments is largely unknown. The objective of the present study was to describe expression and overlaps of airway and systemic T2 biomarkers in a clinically r
Background: Celiac disease (CD) is an autoimmune disease leading to gastrointestinal symptoms and mineral deficiencies. The pathogenetic mechanisms, besides the clear HLA association, are elusive. Among environmental factors infections have been proposed. Covid-19 infection results in a systemic inflammatory response that often also involves the gastrointestinal tract. The aim of the present study
Background: Many pathological processes can disrupt the integrity of the glomerular capillary wall and cause a massive leakage of protein, resulting in nephrotic syndrome (NS). Clinical parameters such as age, sex, renal function, presence of diabetes, and how NS is defined influence the spectrum of underlying diseases. In this study, we examine how these parameters interact.Methods: Age, sex, hem
Background: High plasma copeptin (copeptin), the C-terminal fragment of arginine vasopressin pro-hormone, has been associated with the metabolic syndrome (MetS), diabetes mellitus (DM) development and nephropathy. Here we tested whether elevated copeptin level is associated with later development of the MetS, its individual components and microalbuminuria. Methods: We analysed copeptin at baselin
Magnetotactic bacteria (MTB) are known to biosynthesise single-domain magnetite (Fe3O4) for geomagnetic navigation and their relict magnetosomes (called magnetofossils) can control the magnetic properties of lake and marine sediments. Magnetotactic bacteria also produce greigite (Fe3S4) magnetosomes but, compared to those made of magnetite, relatively little is known about the sedimentary environm
Objective To assess the contemporary prevalence of, and factors associated with angina pectoris symptoms, and to examine the relationship to coronary atherosclerosis in a middle-aged, general population. Methods Data were based on the Swedish CArdioPulmonary bioImage Study (SCAPIS), in which 30 154 individuals were randomly recruited from the general population between 2013 and 2018. Participants
Background: Patients with type 2 diabetes have an increased risk of death and cardiovascular events and people with diabetes or prediabetes have been found to have increased atherosclerotic burden in the coronary and carotid arteries. This study will estimate the cross-sectional prevalence of atherosclerosis in the coronary and carotid arteries in individuals with prediabetes and diabetes, compare
Background. National as well as international Parkinson's disease (PD) treatment guidelines are available to guide clinicians. Previous research has shown that nonmotor symptoms (NMS) are pronounced in late-stage PD and has suggested that current treatment is insufficient and could be improved. Objectives. The aim of this study was to investigate to which degree the national and international trea
Background: Deferred (also known as delayed) cord clamping can improve survival of infants born preterm (before 37 weeks of gestation), but the optimal duration of deferral remains unclear. We conducted a systematic review and individual participant data network meta-analysis with the aim of comparing the effectiveness of umbilical cord clamping strategies with different timings of clamping or wit
Background Familial adenomatous polyposis (FAP) is a rare inherited syndrome that predisposes the patient to cancer. Treatment of FAP-related ampullary lesions is challenging and the role of endoscopic papillectomy has not been elucidated. We retrospectively analyzed the outcomes of endoscopic papillectomy in matched cohorts of FAPrelated and sporadic ampullary lesions (SALs). Methods This retrosp
OBJECTIVES: To investigate whether the relative effectiveness of janus kinase inhibitors (JAKis) versus tumour necrosis factor inhibitors (TNFi) or other biological disease-modifying antirheumatic drugs in rheumatoid arthritis differ by the presence or absence of risk factors for cardiovascular (CV) disease, age, sex and smoking. METHODS: Through Swedish registers, we identified 13 493 individuals
BACKGROUND AND OBJECTIVES: Several pathologic processes might contribute to the degeneration of the cholinergic system in aging. We aimed to determine the contribution of amyloid, tau, and cerebrovascular biomarkers toward the degeneration of cholinergic white matter (WM) projections in cognitively unimpaired individuals. METHODS: The contribution of amyloid and tau pathology was assessed through
BACKGROUND: Metformin use has been associated with improved survival in patients with different types of cancer, but research regarding the effect of metformin on cutaneous melanoma (CM) survival is sparse and inconclusive.OBJECTIVES: To investigate the association between metformin use and survival among patients with CM and diabetes.METHODS: All adult patients with a primary invasive CM between
Purpose: To investigate the possibility to be able to offer left sided breast cancer patients, not suitable for DIBH, an organ at risk saving treatment. Materials and Methods: Twenty patients receiving radiotherapy for left breast cancer in DIBH were enrolled in the study. Planning CT scans were acquired in the same supine treatment position in FB and DIBH. 3DCRT_DIBH plans were designed and optim
AIM: Factors associated with unexpected absence or presence of coronary atherosclerosis in individuals at high/low estimated cardiovascular (CV) risk are largely unexplored. We assessed two extreme phenotypes: 1) no coronary atherosclerosis despite very high CV risk; and 2) severe-extensive coronary atherosclerosis despite low CV risk.METHODS: A multicenter, cross-sectional nationwide, population-
