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Objective. The volume of colonoscopies performed is increasing and differences in colonoscopy practice over time and between centres have been reported. Examination of current practice is important for benchmarking quality. The objective of this study was to examine variations in colonoscopy practice in endoscopy centres internationally. Material and methods. This observational study prospectively
BACKGROUND: To compare the intrinsic virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant with the delta variant in hospitalized adults with coronavirus disease 2019 (COVID-19).METHODS: All adults hospitalized in the Capital Region of Copenhagen with a positive reverse transcription polymerase chain reaction test for SARS-CoV-2 and an available variant dete
Popular Abstract in Swedish Ett av de viktigaste målen för astronomin är att förstå var vi kommer ifrån. Det är naturligtvis många steg som skall förstås, och vart och ett av dessa steg i människans för-förhistoria är komplicerat, så man skall inte förvänta sig att en enskild doktorsavhandling behandlar mer än ett litet hörn av ett av dessa steg. Mitt bidrag gäller förståelsen av hur vår egen galIn order to understand the formation and evolution of the Galaxy it is imperative to know when different components formed. This means at the most basic level that we need to know the ages of stars. The present work demonstrates the many problems inherent in determining the ages of stars through comparison with stellar evolutionary models. Furthermore, solutions to some of these problems are prese
Background and purpose In Sweden, surgery for knee osteoarthritis (OA) in patients younger than 55 years of age has doubled during the last 10 years. We evaluated the use of 3 surgical alternatives: high tibial osteotomy (HTO), unicompartmental arthroplasty (UKA), and total knee arthroplasty (TKA). We also examined the outcome, expressed by rate of revision. Methods The numbers of all procedures d
STUDY OBJECTIVE: Although national variation in short-term prognosis (that is, 30 day mortality) after a patients first hospitalisation for heart failure may depend on individual differences between patients, dissimilarities in hospital practices may also influence prognosis. This study, therefore, sought to disentangle patient determinants from institutional factors that might explain such variat
The Ganges is one of the world's largest rivers and lies at the heart of a body of literature that investigates the interaction between mountain orogeny, weathering and global climate change. Three regions can be recognised in the Ganges basin, with the Himalayan orogeny to the north and the plateaus of peninsular India to the south together delimiting the Ganges alluvial plain. Despite constituti
Background The zinc transporter 8 (ZnT8) was recently identified as a common autoantigen in type 1 diabetes (T1D) and inclusion of ZnT8 autoantibodies (ZnT8Ab) was found to increase the diagnostic specificity of T1D. Objectives The main aims were to determine whether ZnT8Ab vary during follow-up 1 year after diagnosis, and to relate the reactivity of three types of ZnT8Ab to the residual stimulate
Although up to 30% of babies born with haemophilia do not have a family history of the disorder, the remaining 70% are born in families where haemophilia has been diagnosed. It has been estimated that for each male with haemophilia, there are five potential female carriers. Such women will benefit from knowledge of both their genetic (mutation present or not) and phenotype (level of plasma factor
Objectives: The present study evaluates the effect of food intake on 90 biomarkers for cardiovascular disease (CVD) and inflammation with the Proseek Multiplex CVD II kit. Methods: Twenty-two healthy subjects (11 male and 11 females aged 25.9 ± 4.2 years) were investigated. A total of 90 biomarkers were measured before a standardized meal, 30 and 120 minutes thereafter with the Proseek Multiplex C
α-Chymotrypsin immobilized on celite catalyzing a kinetically controlled dipeptide synthesis reaction in acetonitrile medium showed an odd behavior in response to additions of triethylamine to the reaction mixture. This base is used to deprotonate the nucleophilic reagent, l-alaninamide hydrochloride, in order to increase its nucleophilicity and solubility. However, the enzyme performance is appar
Background: Commuting, transportation from the home to the work place has been claimed to increase the material wealth. Although economy and flexibility to choose where to live and work will improve for the individual, several studies have shown that health become aggravated with increased commuting. One plausible explanation to the negative health is reduced social capital. Aim: Our primary hypot
Reuse and recycling were important, but often forgotten, parts of managing the preindustrial fashionable wardrobe. Through researching diaries and extant garments from Swedish collections, the sources reveal everyday textile practices of costly textiles, mending, turning, altering, using old fabric or garments for new, change of parts or color, and reuse of textile material for new fabrics. The soReuse and recycling were important, but often forgotten, parts of managing the preindustrial fashionable wardrobe. Through researching diaries and extant garments from Swedish collections, the sources reveal everyday textile practices of costly textiles, mending, turning, altering, using old fabric or garments for new, change of parts or color, and reuse of textile material for new fabrics. The so
Background: Despite the advancement of electrocardiogram (ECG) monitoring methods, the most important factor influencing diagnostic yield (DY) may still be monitoring duration. Ambulatory ECG monitoring, typically with 24–48 hours duration, is widely used but may result in underdiagnosis of rare arrhythmias. Aims: This study aimed to examine the relationship between the DY and monitoring duration
AIMS: This study aimed to investigate the association between the 'Shrunken pore syndrome' (SPS) and risk of death, 30 day rehospitalization, and health-related quality of life (QoL) in heart failure (HF) patients. SPS is characterized by a difference in renal filtration between cystatin C and creatinine, resulting in a low eGFRcystatin C /eGFRcreatinine ratio.METHODS AND RESULTS: A total of 373 p
Objectives To investigate the prevalence of axial spondyloarthritis (axSpA) in patients with chronic back pain (CBP) of less than 2 years (2y) duration referred to the rheumatologist, the development of diagnosis over time, and patient characteristics of those developing definite (d-)axSpA over 2y. Methods We analysed the 2y data from SPondyloArthritis Caught Early, a European cohort of patients (
Background: Perioperative myocardial injury (PMI) is associated with increased short-term major adverse cardio- and cerebrovascular events (MACCE) and mortality. We evaluated how different phenotypes of PMI based on timing of injury impact long-term MACCE and mortality among patients undergoing major noncardiac surgery (NCS). Methods: A prospective, observational study was carried out in 1290 pati
Background A 1-h algorithm based on high-sensitivity cardiac troponin T (hs-cTnT) testing at presentation and again 1 h thereafter has been shown to accurately rule out acute myocardial infarction. Objectives The goal of the study was to evaluate the diagnostic accuracy of the 1-h algorithm when supplemented with patient history and an electrocardiogram (ECG) (the extended algorithm) for predicti
OBJECTIVES: To examine patient willingness and possible shift in willingness for surgery and to investigate factors associated with this shift, following participation in the digital non-surgical osteoarthritis (OA) treatment program Joint Academy.METHODS: 458 individuals (mean age 62±5.6 years, 67% women) with diagnosed hip or knee were evaluated after six weeks in Joint Academy, comprising educa
BaCON: Ett verktyg för bioinformatikern Bioinformatik är en tvärvetenskaplig disciplin, där datorberäkningar används för att analysera biologiska data. Inom området används många olika datorprogram, flera som en användare kan installera på sin egen dator. Många av dessa program går också att hitta online, med fördelar som att man slipper installera många program på sin egen dator och de använde
Denna studie granskar det urbana hållbarhetsarbetet i Köpenhamn, nämligen deras ”Smart city”- strategi, med fokus på ett specifikt spårningsprojekt som staden startat. Några aspekter som tas upp är integritet, medborgardeltagande och transparens. Som en konsekvens av en ökande urbanisering står städer världen över inför flera urbana utmaningar som kräver att de förändrar hur de planerar och arbeCities around the world are facing a multitude of urban challenges that demand that they change the way they plan and think about their city, with one of the ways of approaching sustainability being the Smart city. A core feature of the Smart city is the idea of collecting large quantities of data on the city, big data, which is then used in various city solutions. In the wake of this, several que
