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OBJECTIVE: To determine the impact of improved glycemic control on the development and progression of retinopathy after the institution of insulin therapy in patients with type 2 diabetes and to assess the relation to IGF-1 and hemostatic variables. RESEARCH DESIGN AND METHODS: In a prospective observational study, 45 type 2 diabetic patients were examined at baseline and 1, 3, 6, 12, and 24 month
High spin states in the nucleus Tc-90 have been identified for the first time via the fusion evaporation reaction (Ni(Ar,3pn)Tc)-Ni-58-Ar-36-Tc-90, at 149 MeV beam energy. The OSIRIS spectrometer with an additional high purity Ge detector at 162-degrees and several particle detectors were used to measure gammagamma and particle-gammagamma coincidences, directional correlations of oriented states (
Aim: To explore whether the phrasing of the questions and the response alternatives would influence the answers to questions about legalisation of euthanasia. Methods: Results were compared from two different surveys in populations with similar characteristics. The alternatives "positive'', "negative'', and "don't know'' (first questionnaire) were replaced with an explanatory text, "no legal sanct
The habitat distribution of red-listed plants, fungi and animals that have been found in the central parts of the parish of Stenbrohult, southern Sweden since 1970 is presented (Tables 1-4). In the centre of the 5 000 ha study area Carl Linnaeus was born in 1707, and he spent his summers there until 1727. In 1971-2002 at least 183 red-listed species have been found, with 73 wood-living beetle spec
Aim: To analyse morbidity and mortality in healthy newborn infants in relation to various routines of post-natal follow-up. Design: cross-sectional study. Setting: maternity care in Sweden. Population: healthy infants born at term between 1999 and 2002 (n = 197 898). Methods: Assessment of post-natal follow-up routines after uncomplicated childbirth in 48 hospitals and data collected from the Swed
Massive MIMO can greatly increase both spectral and transmit-energy efficiency. This is achieved by allowing the number of antennas and RF chains to grow very large. However, the challenges include high system complexity and hardware energy consumption. Here we investigate the possibilities to reduce the required number of RF chains, by performing antenna selection. While this approach is not a ve
The pine sawfly Neodiprion sertifer (Geoffroy) uses the acetate or propionate of (2S,3S,7S)-3,7-dimethyl-2-pentadecanol (diprionol) as pheromone components, with the (2S,3R,7R)-isomer being antagonistic, synergistic, or inactive according to the population tested. In this study, we tested the attraction of males to the acetates of three analogs of diprionol, each missing one methyl group, viz. (2S
Influences on stratospheric aerosol during the first four months following the eruption of Kasatochi volcano (Alaska) were studied using observations at 10700 +/- 600 m altitude from the CARIBIC platform. Collected aerosol samples were analyzed for elemental constituents. Particle number concentrations were recorded in three size intervals together with ozone mixing ratios and slant column densiti
ATP-sensitive K(+) channels (K(ATP) channels) of pancreatic beta-cells play key roles in glucose-stimulated insulin secretion by linking metabolic signals to cell excitability. Membrane phosphoinositides, in particular phosphatidylinositol 4,5-bisphosphates (PIP(2)), stimulate K(ATP) channels and decrease channel sensitivity to ATP inhibition; as such, they have been postulated as critical regulat
The major aim of the study was to investigate whether differences concerning acceptance of dental treatment and amnesia after rectal sedation with midazolam can be explained by temperament traits in the child. Fifty children (1.5- 4.0 years), consecutively referred for dental extractions because of dental trauma or caries, were sedated with midazolam 0.3 mg kg(1) rectally. Level of sedation (state
Implementation of an in-mill biological treatment plant is one solution to the problems associated with closure of whitewater systems. It is, however, important to operate the treatment with low concentration of nutrients in the effluent. The effect on the COD reduction from decreased additions of NH4-N and PO4-P were investigated in three parallel aerobic suspended carrier reactors during treatme
Atmospheric nitrogen (N) dry deposition is an important component in total N deposition. However, uncertainty exists in the assessment of global dry deposition. Here, we develop empirical models for estimating ground N concentrations using NO 2 satellite measurements from the Ozone Monitoring Instrument (OMI) and ground measurements from 555 monitoring sites. Global patterns and trends in the flux
Anaplastic thyroid cancer (ATC) is one of the most malignant tumors, with a median survival of only a few months. The tumorigenic processes of this disease have not yet been completely unraveled. Here, we report an mRNA expression and DNA methylation analysis of fourteen primary ATCs. ATCs clustered separately from normal thyroid tissue in unsupervised analyses, both by RNA expression and by DNA m
Background: Omission of breakfast results in higher glucose and lower insulin and incretin hormone levels after both lunch and dinner. Whether omission of lunch has a similar impact on the following meal is not known. Aim: This study therefore explored whether omission of lunch ingestion affects glucose, islet and incretin hormones after dinner ingestion in healthy subjects. Materials & Method
Ray-Triangle intersection is a fundamental computation in most ray tracing algorithms. The prohibitive cost of the ray-triangle test algorithms, however, limits the utilization of these algorithms in settings with low power budgets, such as mobile systems. In this work, we analyze the precision requirements for ray-triangle intersection and observe that for most of the rays a low-precision is suff
Water-, sanitation-, and hygiene-related diseases are killing many people each year in developing countries, including Rwanda, and children under the age of five are the most vulnerable. This research assessed human waste disposal practices, knowledge on diseases caused by contact with human faeces, and knowledge on causes and prevention of selected WASH-related diseases. One thousand one hundred
X-ray free-electron lasers (FELs), which amplify light emitted by a relativistic electron beam, are extending nonlinear optical techniques to shorter wavelengths, adding element specificity by exciting and probing electronic transitions from core levels. These techniques would benefit tremendously from having a stable FEL source, generating spectrally pure and wavelength-tunable pulses. We show th
Melanoma is a highly metastatic cancer, and its incidence has increased over the past several decades. Angiogenesis is associated with melanoma metastasis and a poor prognosis. Many genetic and epigenetic factors affecting tumour vascularization and metastasis have been investigated, despite the heterogeneity of cancer cells and the complicated mechanisms involved in melanoma. Nemo-like kinase (NL
