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Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
TEDDY-studien avslutad – årsrapport 2024–2025 Diabetesporträtt – Julia Otten Nr 4-5 • År 2026 • Årgång 39 • Utgiven av Svensk förening för Diabetologi DiabetologNytt Höjdpunkter från Nationellt Diabetes- möte i Göteborg *Mounjaro 5, 10 och 15 mg jämfört med Ozempic 1 mg. p<0,001. Primärt effektmått var observerad genomsnittlig förändring av HbA1c från baseline (67 mmol/mol) upp till 40 veckor i st
https://www.teddy.lu.se/sites/teddy.lu.se/files/2026-07/DN_nr_4-5_2026_webb_compr.pdf - 2026-07-22
The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was
TEDDY Årsrapport 2014 1 Årsrapport 2014 TEDDY - Omgivningsfaktorer för typ 1-diabetes och celiaki hos barn Ystad Malmö Helsingborg Kristianstad TEDDY-lab Malmö Simrishamn TEDDY Årsrapport 2014 2 Innehållsförteckning 1. Sammanfattning – ”TEDDY har ett resultat” 2. Bakgrund TEDDY-studien 3. Typ 1-diabetes - är en sjukdom i två steg 4. Glutenintolerans – celiaki - utvecklas också i två steg 5. TEDDY-
https://www.teddy.lu.se/sites/teddy.lu.se/files/2014_teddy_arsrapport.pdf - 2026-07-23
This study seeks to examine the nationalist ideological positioning of the Swedish parliament’s only self-proclaimed nationalist party, the Sweden Democrats (SD). The understanding of nationalism differs heavily in the social sciences and a variety of distinctions have been proposed in the study of it. The most common of these distinctions is the one between civic and ethnic nationalism. The metho
LUNDS UNIVERSITET Tidplan HT2023 230201 HT23: 230828 – 240114 HT23 LUND HELSINGBORG Termin 1 SOPA12 HT23 (93 stud) SOCIALT ARBETE SOM ÄMNE OCH PROFESSION (30 hp) Mån 28/8 – Sön 14/1 (fre 12/1) HT23 (66 stud) SOCIALT ARBETE SOM ÄMNE OCH PROFESSION (30 hp) Mån 28/8 – Sön 14/1 (fre 12/1) Termin 2 SOPB21 VT23 (90 stud) SAMHÄLLSVETENSKAP OCH SOCIALT ARBETE (30 hp) Mån 28/8 – Sön 14/1 (fre 12/1)) VT23 (
https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2023-02/Tidplan%20HT23.pdf - 2026-07-22
Namnlös Reading list for Sustainable Services (SEMA54), 7,5 credits The reading list was approved by the Board of the Department of Service Studies 2023-05-24. The reading list is valid from 2023-11-29. Högskolan i Borås (latest). Guide till Harvardsystemet. Borås: Högskolan i Borås. [51 p.]. Https://www.hb.se/biblioteket/akademiskt-sprak/referera-till-kallor/guide-till-harvardsystemet/ Benn, Suza
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2023-05/LL_SEMA54_eng_HT23_230524.pdf - 2026-07-22
https://www.geriatrik.lu.se/geriatrics/education - 2026-07-21
BACKGROUND: After amputation, the sensorimotor cortex reorganizes, and these alterations might influence motor functions of the remaining extremities.OBJECTIVE: The authors examined how amputation of the dominant or nondominant upper or lower extremity alters deftness in the intact limbs.METHODS: The participants were 32 unilateral upper- or lower-extremity amputees and 6 controls. Upper-extremity
Gerhard Schurz [2001, Journal for General Philosophy of Science, 32, 65-107] has proposed to reconstruct auxiliary hypothesis addition, e.g., postulation of Neptune to immunize Newtonian mechanics, with concepts from non-monotonous inference to avoid the retention of false predictions that are among the consequence-set of the deductive model. However, the non-monotonous reconstruction retains the
This essay examines the personifications of Death in Markus Zusak’s The Book Thief (2005), Christopher Moore’s A Dirty Job (2006) and George Pendle’s Death: A Life (2008). The personifications are analysed in terms of gender, anthropomorphism, (im)mortality, agency in conceptual death and attitude towards their occupation as Death. The personifications are also compared to previous portrayals in r
