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Purpose: To compare the performance of targeted temperature management (TTM) at 33 °C using intravascular (IC) vs. surface-cooling (SFC) devices after out-of-hospital cardiac arrest (OHCA). Methods: A post hoc analysis including OHCA patients randomized to hypothermia in the TTM2-trial (NCT02908308) comparing hypothermia with normothermia. The main outcome was cooling performance, defined as the p
Cortical interneuron deficiencies, particularly involving the somatostatin (SST) subtypes, contribute to neurological and neuropsychiatric disorders. These interneurons are difficult to derive in vitro from human embryonic stem cells (hESCs) due to their late embryonic development and dependence on glial interaction. To this end, we developed a three-dimensional co-culture model of hESC-derived ne
Introduction: Cranioplasty, a surgical procedure to restore skull integrity and aesthetic contour following decompressive craniectomy, poses challenges in material selection and timing, driven by the lack of guidelines and ongoing regulatory changes. Research question: This study aimed to provide an overview of current cranioplasty practices in Europe, explicitly addressing a potential shift towar
We describe the presumably first intentional ABO-incompatible deceased-donor kidney and pancreas transplantation with a severe antibody-mediated rejection during a rebound of isoagglutinins. Rejection was successfully treated with eculizumab, which inhibits the terminal pathway of complement. Complement analysis (C3, C3d,g, and a modified assay of classical complement-related hemolytic function) d
BACKGROUND: Head impacts are common in contact sports such as boxing and occur at times of elevated core body and brain temperatures induced by the exercise. Following impact, elevated brain temperature may lead to the development of exacerbated brain injury that can be monitored by blood biomarkers. Blood-brain biomarkers S100B and glial fibrillary acidic protein (GFAP) reflect glial injury; neur
Borrelia burgdorferi sensu lato is a tick-borne pathogen that causes Lyme disease. The characterization of membrane proteins from this and other pathogens may yield a better understanding of the mechanisms of infection and information useful for vaccine design. Characterization of the highly hydrophobic Borrelia outer membrane component P13 from a mutant (OspA- OspB- OspC- and OspD-) strain was un
BACKGROUND: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung cancer remains unclear. METHODS: We performed single and combined multiple instrumental variable Mendelian randomization analysis by an inverse-weighted method, in addition to a
The protein parkin, encoded by the PARK2 gene, is vital for mitochondrial homeostasis, and although it has been implicated in Parkinson’s disease (PD), the disease mechanisms remain unclear. We have applied mass spectrometry-based proteomics to investigate the effects of parkin dysfunction on the mitochondrial proteome in human isogenic induced pluripotent stem cell-derived neurons with and withou
PURPOSE: Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treatment. We evaluated the use of vemurafenib, a small-molecule BRAF inhibitor with immunomodulatory properties, as priming before TIL harvest and adopti
Although the involvement of the tumor suppressor gene p53 in normal hematopoiesis is uncertain, it can give rise to differentiation signals in leukemic cells. It is not clear, however, whether differentiation merely is a consequence of the ability of p53 to arrest cell proliferation or whether hitherto unknown molecular mechanisms are responsible for the p53-mediated differentiation. To further ex
Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avert climate change and environmental disaster. In particular, they fail to address the need for a fundamental cultural transformation, which involves a collective shift in mindsets (values, beliefs, worldviews and associated inner human capacities). Whilst scholars and practitioners are
Optical imaging utilize light to analyze biological tissues in detail, non-invasively and without harmful radiation. Examples include ultrasound optical tomography and photoacoustic imaging; both use a limited number of wavelengths. Diffuse reflectance spectroscopy, another optical technique, covers a continuous wavelength range, but without generating an image. This study focuses on extended-wave
BACKGROUND: Despite pain control being a top priority in end-of-life care, pain continues to be a troublesome symptom and comprehensive data on pain prevalence and pain relief in patients with different diagnoses are scarce.METHODS: The Swedish Register of Palliative Care (SRPC) was used to retrieve data from 2011 to 2022 about pain during the last week of life. Data were collected regarding occur
Mutations in the NRF2-KEAP1 pathway are common in non-small cell lung cancer (NSCLC) and confer broad-spectrum therapeutic resistance, leading to poor outcomes. The cystine/glutamate antiporter, system xc-, is one of the >200 cytoprotective proteins controlled by NRF2, which can be non-invasively imaged by (S)-4-(3-18F-fluoropropyl)-l-glutamate ([18F]FSPG) positron emission tomography (PET). Throu
Purpose: Resilience has been suggested as an important predictor of both physical and mental health-related quality of life in breastcancer patients. However, it is unclear why resilient women handle their diagnosis better, not only mentally, but also physically. Theaim of this study was to investigate paths between resilience, physical activity, and mental, physical, and global health-related qua
Seminarieserie våren 2026 - Tema AI | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska f
https://www.lth.se/cee/workshops-konsultstoed-och-oevriga-aktiviteter/seminarieserie-vaaren-2026-tema-ai/ - 2026-06-08
Inredningsarkitekt | Sveriges akademikers centralorganisation Hoppa till huvudinnehåll till startsida Öppna sökruta Öppna Huvudmeny Sök på saco.se Om Saco Kontakt Anställda hos Saco Saco studentråd Sacos styrelse Sacos revisorer Sacos organisation Sacos styrelse Kontaktuppgifter Sacos styrelse Verksamhetsberättelse och årsredovisning Federationen och förbunden Medlemsstatistik Förbunden Saco Hälso
https://www.saco.se/studier/studieval/yrken-a-o/inredningsarkitekt/ - 2026-06-29
Civilingenjör | Sveriges akademikers centralorganisation Hoppa till huvudinnehåll till startsida Öppna sökruta Öppna Huvudmeny Sök på saco.se Om Saco Kontakt Anställda hos Saco Saco studentråd Sacos styrelse Sacos revisorer Sacos organisation Sacos styrelse Kontaktuppgifter Sacos styrelse Verksamhetsberättelse och årsredovisning Federationen och förbunden Medlemsstatistik Förbunden Saco Hälso- och
https://www.saco.se/studier/studieval/yrken-a-o/civilingenjor/ - 2026-06-29
Postadress Box 192, 221 00 Lund Besöksadress Helgonavägen 3, LUND Telefon direkt: +46 46 222 72 20, växel: 046-222 00 00 Webbadress http://www.ht.lu.se Fakul te tsstyre lsen Kris- och beredskapsplan för Humanistiska och teologiska fakulteterna Inledning En kris kan beskrivas som en svår, oftast hastigt uppkommen situation med personella, materiella eller etiska och förtroendemässiga skador eller m
Civilingenjörsutbildning i medicin och teknik utbildningsplan Sida 1 av 7 Utbildningsplan Civilingenjörsutbildning i medicin och teknik - Programkod: TAMTE - Omfattning: 300 högskolepoäng - Tillträdesnivå: Grundnivå - Beslutsfattare: Programledning BME - Utbildningsplanens giltighet: 2024/2025 - Utbildningsplanen fastställd: 2024-02-15 1 Syfte och mål 1.1 Syfte Medicin och teknik är ett tvärvetens
