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Abstract Dopamine as a neurotransmitter was discovered in the late 1950s. The dopaminergic system is one of the most well studied neurotransmitter systems in the brain. It is involved in many important functions, such as motor function control; reward, reinforcement, motivation, associative learning, salience information encoding; cognition etc. Disturbances of the dopaminergic system may result
Personuppgifter blir allt viktigare i den digitala ekonomin. Omfattningen av insamling och behandling ökar och riskerar att hota den personliga integriteten. Trots att personlig integritet och respekten för privatlivet räknas som som en mänsklig rättighet har dessa en väldigt svag position relativt andra rättigheter och samhälleliga behov. Detta ter sig ganska underligt eftersom den personliga intPersonal data is becoming increasingly important in the digital economy. The scope of collection and treatment increases and may threaten personal integrity. Although privacy is regarded as human right, privacy has a very weak position relative other rights and social needs. This is quite strange as privacy is often considered a prerequisite for many of the traditional rights such as freedom of sp
Deposition of ferroelectric hafnium zirconium oxide (HZO) on semiconductor samples with Atomic Layer Deposition (ALD) has proven to be a viable method of production. But while the physical processes of ALD deposition is relatively well know, there exists some gaps in knowledge about different parameters for the ALD and the resulting depositions. This work is about analysing mainly how the purge ti
Granular Activated Carbon (GAC) is nowadays suggested as a fourth (quaternary) treatment step at municipal wastewater treatment plants to remove certain chemicals and particularly organic micropollutants (OMPs). This work investigated the different factors that affect the performance of the GAC filter for the removal of micropollutants in a municipal wastewater treatment plant. This study is purel
Does perfluorooctane sulfonate (PFOS) and perfluorooctanate (PFOA) exposure disrupt the menstrual cyclicity? The female reproductive system may be sensitive to PFOA exposure, with longer menstrual cycle length at higher exposure. PFOS and PFOA are persistent man-made chemicals. Experimental animal studies suggest they are reproductive toxicants but epidemiological findings are inconsistent. A cros
The ever increasing data rates in wireless communication require analog to digital converters (ADCs) with greater requirements on speed and accuracy, while being power efficient to prolong battery life. This dissertation contains an introduction to the field and five papers that focus on the continuous-time (CT) Delta-Sigma modulator (DSM) as ADC. Paper I analyses the performance degradation of d
Aims. The aim of this paper is to explore and map the age and abundance structure of the stars in the nearby Galactic disk. Methods. We have conducted a high-resolution spectroscopic study of 714 F and G dwarf and subgiant stars in the Solar neighbourhood. The star sample has been kinematically selected to trace the Galactic thin and thick disks to their extremes, the metal-rich stellar halo, sub-
Numerous products from the food industry contain fruit and/or berries, in the form of fillings or ingredients, e. g. in yoghurt, some bread products/cereal products, ice cream, etc. In order to produce these ingredients and improve their characteristics, many processing techniques are available. This thesis focuses on dehydration methods that take into account the fragile and complex cellular tiss
Popular Abstract in Swedish Njurarna spelar en central roll i de förändringsprocesser som anpassar kvinnans kropp till en graviditet. Många av de förändringar som sker mot slutet av en normal graviditet, påminner om de förändringar man ser vid preeklampsi, havandeskapsförgiftning, om än mindre uttalade. Preeklampsi är ett allvarligt risktillstånd som kan uppkomma under graviditet och en av de störThe kidneys play a pivotal role in the adaptive physiology of the pregnant woman, presenting some changes at term similar to the changes found in preeclampsia – a state of increased risk of fetal and maternal morbidity and mortality. The aim of these investigations was to explore possible similarities in blood pressure regulation, renal function and structure in normal term and preeclamptic pregna
Projektet Renässans 1.5 utgår ifrån det faktum att det i den traditionella produktutvecklingsprocessen normalt krävs flera iterationer i processens olika faser innan man kan nå en acceptabel kompromiss mellan estetiska krav och konstruktions- och tillverkningskrav. Den snabba utvecklingen inom optimeringsteknik och kunskapsbaserad konstruktion gör det möjligt att integrera ett datorbaserat formgivThe Renaissance 1.5 project was based on the observation that in traditional product development, several iterations are needed to obtain a compromise between engineering, manufacturing constraints and aesthetics. The rapid advances in optimisation methods and in knowledge-based engineering (KBE) make it possible to integrate engineering and manufacturing constraints in a computer-based industrial
The purpose of this study was to investigate women's wishes and need for knowledge concerning sexuality and relationships in connection with gynecological cancer. A total of 11 women were interviewed following the completion of their treatment for gynecological cancer. The data was analyzed using latent content analysis. Two main categories were identified: "The absence of knowledge about the body
Particles containing soot, or black carbon, are generally considered to contribute to global warming. However, large uncertainties remain in the net climate forcing resulting from anthropogenic emissions of black carbon (BC), to a large extent due to the fact that BC is co-emitted with gases and primary particles, both organic and inorganic, and subject to atmospheric ageing processes. In this stu
Popular Abstract in Swedish Huvudsyftet med avhandlingen är att formulera en teoretiskt och empiriskt förankrad konsultationsmodell för psykologer i skolsammanhang. Idéer och handlingsstrategier tydliggörs så att de kan tillämpas, värderas och vidareutvecklas av andra yrkesutövare. De tänks även kunna utgöra en referensram för psykologers, specialpedagogers och andra specialisters teamarbete. VidaThe primary aim of this thesis is to formulate a theoretically and empirically based consultation model for psychologists in school contexts. Ideas and strategies are clarified so that they can be applied, evaluated, and further developed by other professionals. The model has been constructed with an interactional approach, with the stress on patterns of interaction between grown-ups and children
Methanol as an alternative fuel in internal combustion engines has an advantage in decreasing emissions of greenhouse gases and soot. Hence, developing of a high performance internal combustion engine operating with methanol has attracted the attention in industry and academic research community. This paper presents a numerical study of methanol combustion at different start-of-injection (SOI) in
Wrap Your Troubles into Dreams, är ett praktikbaserat forskningsprojekt. Undersökningen berör stadsomvandlingsprocesser i Stockholmsområdet, speglade genom två politiska förhållningssätt gestaltat i staden: genomförandet av det funktionsseparerade Stockholms City (under 1960-talet) och de senaste decenniernas privatisering av stadsrummet. I forskningen har jag utgått från två platser som i motreakWrap Your Troubles into Dreams is a practice-based artistic research project. The study investigates city transformation processes in the Stockholm area, by viewing them through two political attitudes expressed in the city; the introduction of the function-separated Stockholm City area (during the 1960s) and the privatisation of urban space during the last few decades. I have based my research on
Ambient fine particulate matter PM2.5 (particles with a diameter smaller than 2.5 μm) has been associated with cardiovascular and respiratory morbidity and mortality. It has been shown that biomass burning for heat production purposes can generate large amounts of fine particles. Thus characteristics of particle emissions from biofuel combustion may be important in the assessment of health effects
Popular Abstract in Swedish ”Behandlingen av trafikflöde vid trafiksäkerhetsanalyser - ett icke-parametriskt angreppssätt applicerat på oskyddade trafikanter” Det finns en lång tradition av att beakta trafikflöden inom trafiksäkerhetsområdet. Inverkan av flödet har dock ofta betraktats som så självklart att det använts utan eftertanke. I denna avhandling kan jag däremot visa att relationen mellaThe treatment of flow in the area of traffic safety has a long tradition. The influence flow has on the number of accidents is, however, often considered so obvious that it tends to be trivial. In this thesis I can show that the relation between flow and accidents holds interesting information. In order to compare countermeasures, or conduct other types of traffic safety comparisons where the flo
Intracerebral haemorrhage and small vessel ischaemic stroke (SVS) are the most acute manifestations of cerebral small vessel disease, with no established preventive approaches beyond hypertension management. Combined genome-wide association study (GWAS) of these two correlated diseases may improve statistical power to detect novel genetic factors for cerebral small vessel disease, elucidating unde
As the competition between destinations grows, the need to stand out and offer memorable and unique experiences also grows. Culinary experiences and activities with elements of “the local” are a growing niche, which mirrors the trend of knowing where the food originates, and that it has been grown, produced, and transported in an ecologically, socially and culturally sustainable way. To be able as
It is well established that high ambient heat could cause congenital abnormalities resulting in miscarriage or stillbirth among certain species of mammals. However, this has not been systematically studied in real field settings among humans, despite the potential value of such knowledge for estimating the impact of global warming on the human species. This study sought to test the hypothesis that
