Filetype
Lipid nanoparticles (LNPs) are clinically approved for mRNA-based vaccines and liver-targeted siRNA delivery. However, poor nucleic acid delivery efficiency limits their application in extrahepatic tissues and tumors. Here, using live-cell and super-resolution microscopy, we identify multiple distinct steps of inefficiencies in the cytosolic delivery of both siRNA and mRNA cargoes. Membrane damage
The ECG diagnosis of LVH is predominantly based on the QRS voltage criteria, i.e. the increased QRS complex amplitude in defined leads. The classical ECG diagnostic paradigm postulates that the increased left ventricular mass generates a stronger electrical field, increasing the leftward and posterior QRS forces. These increased forces are reflected in the augmented QRS amplitude in the correspond
Recent studies of selective auditory attention have demonstrated that neural responses recorded with electroencephalogram (EEG) can be decoded to classify the attended talker in everyday multitalker cocktail-party environments. This is generally referred to as the auditory attention decoding (AAD) and could lead to a breakthrough for the next-generation of hearing aids (HAs) to have the ability to
The recently developed Phase-Scaled Reassignment (PSR) can estimate phase-difference between two oscillating transient signals with high accuracy. However, in low signal-to-noise ratios (SNRs) the performance of commonly applied reassignment techniques is known to deteriorate. In order to reduce variance in low SNR, we propose a multitaper PSR (mtPSR) method for phase-difference estimation between
Coherence is a useful measure in many engineering applications. Here, we focus on the case where the input signal to a linear system can be measured free from noise, but the output signal is perturbed by noise. A novel expression for the expectation of a multitaper magnitude squared coherence estimate for this case is presented and verified through numerical evaluation. Additionally, the expressio
Smart microscopy is transforming life sciences by automating experimental imaging workflows and enabling real-time adaptation based on feedback from images and other data streams. This shift increases throughput, improves reproducibility, and expands the functional capabilities of microscopes. However, the current landscape is highly fragmented. Academic researchers often develop custom solutions
Transient activation of fibroblasts into contractile myofibroblasts is essential for extracellular matrix (ECM) production and remodeling during wound healing and tissue regeneration. While ECM-dependent mechanisms mediating transient activation is well studied, how fibroblasts switch from transient to a persistently activated state and drive fibrosis and aberrant tissue repair in diseases such as
Group A Streptococcus (GAS) causes extensive global morbidity and rising rates of invasive disease, for which clinical outcomes remain poor despite antibiotic treatment of susceptible strains. This limitation of current therapy underscores the need for alternative or adjunctive approaches. Antibody-based interventions represent a promising but underexplored strategy. Historically, the streptococca
Popular Abstract in Swedish Hur påverkas djurplanktonsamhällen av klimatförändringar och vilken betydelse har vilostadier? Populärvetenskaplig sammanfattning av “Ecology of zooplankton communities: climate, dormancy and benthic-pelagic coupling”, doktorsavhandling i Limnologi vid Ekologiska institutionen, Lunds Universitet, 2003. Djurplankton är sjöars motsvarighet till betande kossor ochThis thesis describes how influences, such as top down and bottom up forces, shape zooplankton communities in shallow lakes. I have also extended the traditional food-web theory by investigating the effects of climate on total biomass, taxonomic composition, and temporal properties of zooplankton communities. A field experiment showed that the total biomass of both phytoplankton and zooplankton in
Objectives: To test the utility of the World Health Organization (WHO) and International Society of Nephrology/Renal Pathology Society (ISN/RPS) criteria for lupus nephritis (LN) in systemic lupus erythematosus (SLE) and the American College of Rheumatology renal response criteria (ACR-RRC) for renal follow-up in an observational cohort. Method: All 52 biopsy-verified cases of LN during 19 years w
HEKM22 Draft Schedule _07022018 Spring 2018, HEKM22 7,5 credits 1 Depar tment of Human Geography Human E co logy D i v i s ion HEKM22 Methods in Human Ecology Schedule Week Date Time Room Activity Topic Teacher 12 INTRODUCTION: 21/03 13-15 Malmö Lecture Introduction to the course and thinking about methods in research VR 23/03 10-12 Rio Lecture Overview of how to carry out interviews VR 13 INTERVI
https://www.keg.lu.se/sites/keg.lu.se/files/hekm22_schedule_20022018.pdf - 2026-06-25
PowerPoint-presentation Civil society elites in Europe ESA SEMINAR, HÅKAN JOHANSSON, LUND UNIVERSITY, SWEDEN JANUARY 2024 Thematic studies and research questions •What avenues lead to key and inflential positions in civil society? •By whom, how, and on what grounds is civil society elites power contested? •Do elite groups in civil society interact, or integrate, with other elite groups? •What qual
https://www.soch.lu.se/sites/soch.lu.se/files/2024-01/Civil%20Society%20Elites,%20Presentation%20Jan%202024.pdf - 2026-06-25
Header 1 2021-01-25 1 Peer reviewed publications (data and/or co-authors at the national 7T facility) [1] [1-29] 1. Novén, M., Schremm, A., Horne, M., Roll, M., Cortical thickness and surface area of left anterior temporal areas affects processing of phonological cues to morphosyntax, Brain Research 2021,1750:147150 2. Wiggermann, V., Mackay, A. L., Rauscher, A., Helms, G., In vivo investigation o
https://www.lbic.lu.se/sites/lbic.lu.se/files/publications2021jan.pdf - 2026-06-25
Microsoft Word - COSM34 2020 Schedule (2020.11.16).docx 1 COSM34 Development Theories and Issues in Asia Autumn Semester 2021 Course director: Nicholas Loubere E-mail: Nicholas.loubere@ace.lu.se Period: 1 November – 30 November 2021 Office hours: By appointment Teaching 9 Lectures 2 Seminars Readings Students are required to complete all the required readings prior to class. Students, in groups, a
https://www.ace.lu.se/sites/ace.lu.se/files/2021-10/COSM34_Schedule_2021.pdf - 2026-06-25
PowerPoint Presentation AI Art and Copyright LL.D, SENIOR LECTURER JOHAN AXHAMN AI Art and Copyright 1. Copyright 2. Copyright and artificial intelligence Copyright Copyright • Subject matter: Literary and artistic works • Requirement for protection: Originality – ”author’s own intellectual creation”, ”free and creative choices”, ”reflects the author’s personality” General justifications for copyr
Open Source Software-policy can influence the global economy Open Source Software-policy can influence the global economy CIRCLE – CENTRE FOR INNOVATION RESEARCH | LUND UNIVERSITY POLICY BRIEF 01 | 2023 CIRCLE POLICY BRIEF | 01-2023 Open Source Software-policy can infuence the global economy Open Source Software has become an important knowledge asset in modern economies and has gained increasing
https://www.circle.lu.se/sites/circle.lu.se/files/2026-03/CirclePolicyBrief_2023-01_NEW.pdf - 2026-06-25
