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Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. The neuropathologic hallmarks of AD have been observed also in cognitively healthy individuals, which has led to the assumption that the disorde

The standard model (SM) of particle physics is spectacularly successful, yet the measured value of the muon anomalous magnetic moment (g - 2)mu deviates from SM calculations by 3.6 sigma. Several theoretical models attribute this to the existence of a "dark photon," an additional U(1) gauge boson, which is weakly coupled to ordinary photons. The PHENIX experiment at the Relativistic Heavy Ion Coll

Context The relationship of platelet function testing measurements with outcomes in patients with acute coronary syndromes (ACS) initially managed medically without revascularization is unknown. Objective To characterize the differences and evaluate clinical outcomes associated with platelet reactivity among patients with ACS treated with clopidogrel or prasugrel. Design, Setting, and Patients Pat

This report focuses on models of chloride ingress into concrete that are based on mathematical solutions of Fick's second law. In recent years a lot of confusion has been identified concerning these models. In some cases time-dependencies of diffusivity have been used in a mathematically incorrect way. In other cases field and laboratory data from one way of describing the time-dependency of these

Predicted alterations in belowground plant-allocated C as a result of environmental change may cause compositional shifts in soil microbial communities, and it has been hypothesized that such alterations will influence C mitigation in forest ecosystems. In order to investigate to what degree living trees influence the abundance and activity of mycorrhizal fungi, saprotrophic fungi, and bacteria we

The International Commission on Stratigraphy and the IUGS Executive Committee have recently approved a Global Standard Stratotype-section and Point (GSSP) defining the base of the second stage of the Furongian Series, Cambrian System. This stage is named the Jiangshanian Stage, after Jiangshan City, western Zhejiang Province, China, where the GSSP is located. The GSSP is exposed in a natural outcr

In the coming years, it is anticipated that if we continue with the same pace of energy consumption, communities will continue to face three major challenges; a mounting increase in energy demands, pollution, and global warming. On a local scale, Egypt is experiencing one of its most serious energy crises in decades. The energy consumed in indoor cooling and heating is the biggest portion of total

High PHA production and storage using palm oil mill effluent (POME) was investigated using a laboratory batch Bio-PORec (R) system under aerobic-feeding conditions. Results showed that maximum PHA was obtained at a specific rate (q(p)) of 0.343 C-mol/C-mol h when air was supplied at 20 ml/min. The PHA yield was found to be 0.80 C-mol/C-mol acetic acid (HAc) at microaerophilic condition and the mas

Popular Abstract in Swedish Hjärnan är ett av människans viktigaste organ och är det centra som styr våra känslor, minnen och sociala färdigheter. Hjärnan är också det organ som signalerar till musklerna i kroppen att utföra rörelser. När en person drabbas av Parkinsons sjukdom minskar signaleringen till musklerna, vilket medför att det blir svårt att röra sig och stelhet uppstår. Sjukdomen beror Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. For decades, studies have therefore been made in mouse and other model organisms in order to elucidate key-factors that can be used for

The Greenland ice core from NorthGRIP (NGRIP) contains a proxy climate record across the Pleistocene-Holocene boundary of unprecedented clarity and resolution. Analysis of an array of physical and chemical parameters within the ice enables the base of the Holocene, as reflected in the first signs of climatic warming at the end of the Younger Dryas/Greenland Stadial 1 cold phase, to be located with

Negative pressure wound therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer reviewed publications are available describing its use. Despite this, there remains uncertainty regarding several aspects of usage. In order to respond to this gap a global expert panel was convened to develop evidence-based recommendations describing the use of NPWT. In this paper the result

Syfte: Uppsatsen ämnar bidra till den internationella ”Corporate Governance”-litteraturen genom att analysera samband mellan den totala ersättningen till VD och ägarförhållandena i företagen mellan åren 2005-2009. Metod: Metoden som används är kvantitativ och har ett deduktivt förhållningssätt eftersom den baseras på tidigare forskningsresultat och teorier. Vidare analyseras relationerna mellan in

This study contributes to existing theory by underlining that product brands do have a gender. In addition, the results of this study show that the need for product gender congruence is minimized in Generation Y. Therefore, rethinking the traditional gender stereotyping of products may have more consumer appeal by being marketed to both sexes, or at least to emphasize more of the products attribut

Som en följd av att informationskompetens lyfts fram i Bolognaprocessen som ett betydelsefullt element i all högre utbildning har ämnet uppmärksammats i stigande grad inom universitetsvärlden. Bolognaprocessen har även föranlett ändringar i svensk lagstiftning som gör kursplaner till juridiskt bindande dokument. Kursplanernas lärandemål måste examineras för att man ska kunna säkerställa att de har

This paper addresses the problem of urban transport management in Sofia ? the capital city of Bulgaria. It highlights the tensions and contradictions in the current policy and practice and suggests that the adoption of mobility management in policy making would elevate municipal capacity to deal with complex transport-environment conflicts and set the framework for a sustainable development of the

Den 11 september 2001 innebar början på en stor förändring i amerikansk inrikes och utrikespolitik. I kriget mot terrorismen har en omfattande diskriminering skett av icke-amerikanska medborgare både inom landets gränser såväl som utanför. För att rättfärdiga detta för sitt eget folk samt det internationella samfundet har man i politiken och retoriken skapat bilden av "den andre" som ett

Islands? characteristics provide several advantages as laboratory for studying 100% renewable energy sources (RES) systems. Their isolation makes them a ?unique laboratories, to gain knowledge and understanding of people/environment relationships? ; to prove its feasibility and acquire the needed knowledge for such systems to work; to be pioneer project, basis of other islands? projects and even a

The interest in putting a price on carbon emissions is increasing in pace with the urgency of climate change. In this article we compare the adoption of one such policy instrument, carbon taxation, in the cases of Sweden and Mexico. We use a theoretical framework that focuses on economic and environmental factors influencing the policy process via distinct policy areas, as well as the mechanisms t

BACKGROUND/AIMS: This study represents an external validation with model updating of the online DIGIROP-Prescreen and DIGIROP-Screen 2.0 prediction models, incorporating ≥14 days of parenteral nutrition as an additional predictor, to identify infants requiring treatment for retinopathy of prematurity (ROP) in a contemporary Swedish cohort, estimate potential cost savings and compare DIGIROP perfor