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Analysing analyses – An approach to combining several risk and vulnerability analysis
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Dissatisfied patients after total knee arthroplasty.
Background and purpose - In 2003, an enquiry by the Swedish Knee Arthroplasty Register (SKAR) 2-7 years after total knee arthroplasty (TKA) revealed patients who were dissatisfied with the outcome of their surgery but who had not been revised. 6 years later, we examined the dissatisfied patients in one Swedish county and a matched group of very satisfied patients. Patients and methods - 118 TKAs i
Results and recommendations from an intercomparison of six Hygroscopicity-TDMA systems
The performance of six custom-built Hygrocopicity-Tandem Differential Mobility Analyser (H-TDMA) systems was investigated in the frame of an international calibration and intercomparison workshop held in Leipzig, February 2006. The goal of the workshop was to harmonise H-TDMA measurements and develop recommendations for atmospheric measurements and their data evaluation. The H-TDMA systems were co
Limitations in the Use of Unipolar Charging for Electrical Mobility Sizing Instruments: A Study of the Fast Mobility Particle Sizer
A comparison between three different types of particle sizing instruments (fast mobility particle sizer, FMPS; electrical low pressure impactor, ELPI; and scanning mobility particle sizer, SMPS) and one condensation particle counter (CPC) was made to compare instrument response in terms of size distributions and number concentration. Spherical oil droplets in 39 different sizes, with geometric mea
Mothers, places and risk of hospitalization for childhood asthma: a nationwide study from Sweden: Epidemiology of Allergic Disease.
This study examines whether neighbourhood deprivation increases the risk of hospitalization for childhood asthma, after accounting for individual-level maternal socio-demographic characteristics.
Knee cartilage assessment with MRI (dGEMRIC) and subjective knee function in ACL injured copers: a cohort study with a 20 year follow-up.
To assess knee cartilage quality and subjective knee function, 20 years after injury in anterior cruciate ligament (ACL) injured copers.
Subsequent leukaemia in autoimmune disease patients.
Previous studies have shown that patients diagnosed with some autoimmune (AI) diseases are at an increased risk of leukaemia but limited data are available on survival. We systematically analysed the risks (standardized incidence ratio, SIR) and survival (hazard ratio, HR) in nine types of leukaemia among 402 462 patients hospitalized for any of 33 AI diseases and compared to persons not hospitali
Fine-particle emissions from solid biofuel combustion studied with single-particle mass spectrometry: Identification of markers for organics, soot, and ash components
The effects of combustion phase and fuel on smoke particle emissions from a wood stove operated with three different wood fuels and from a corn stove were investigated. A single-particle mass spectrometer (aerosol time of flight mass spectrometer (ATOFMS)) was used for time-and size-resolved chemical signatures and a scanning mobility particle sizer (SMPS) was used for online mobility size distrib
The presence of rheumatoid nodules at early rheumatoid arthritis diagnosis is a sign of extra-articular disease and predicts radiographic progression of joint destruction over 5 years
Objective: Radiographic damage is an important outcome in rheumatoid arthritis (RA). The disease course varies considerably, and there is a need for simple and reliable prognostic markers. The aim of the study was to determine the utility of early signs of extra-articular disease, manifested as rheumatoid nodules (RN), in predicting radiographic outcome. Methods: In a cohort (n = 1589) of consecut
Decrease in the incidence of total hip arthroplasties in patients with rheumatoid arthritis - results from a well defined population in south Sweden
Introduction: One aim of modern pharmacologic treatment in rheumatoid arthritis (RA) is to prevent joint destruction and reduce the need for surgery. Our purpose was to investigate secular trends in the incidence of primary total hip and knee arthroplasties in a well defined sample of patients with RA. Methods: Prevalent cases with RA in 1997 and incident cases from 1997 to 2007 in a community bas
Soot reference materials for instrument calibration and intercomparisons: a workshop summary with recommendations
Soot, which is produced from biomass burning and the incomplete combustion of fossil and biomass fuels, has been linked to regional and global climate change and to negative health problems. Scientists measure the properties of soot using a variety of methods in order to quantify source emissions and understand its atmospheric chemistry, reactivity under emission conditions, interaction with solar
Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders: randomised controlled trial.
Background Individual-based cognitive-behavioural therapy (CBT) is in short supply and expensive. Aims The aim of this randomised controlled trial (RCT) was to compare mindfulness-based group therapy with treatment as usual (primarily individual-based CBT) in primary care patients with depressive, anxiety or stress and adjustment disorders. Method This 8-week RCT (ClinicalTrials.gov ID: NCT0147637
Respiratory tract deposition of inhaled wood smoke particles in healthy volunteers
Background: Respiratory tract deposition of air pollution particles is a key to their adverse health effects. This study was aimed to determine the size-resolved deposition fraction (DF) of sooty wood smoke particles in the lungs of healthy subjects. The type of wood smoke investigated is typical for household air pollution from solid fuels, which is among the largest environmental health problems
Using Patchy Particles to Prevent Local Rearrangements in Models of Non-equilibrium Colloidal Gels
Simple models based on isotropic interparticle attractions often fail to capture experimentally observed structures of colloidal gels formed through spinodal decomposition and subsequent arrest: the resulting gels are typically denser and less branched than their experimental counterparts. Here, we simulate gels formed from soft particles with directional attractions ("patchy particles"), designed
Soft particles in an electric field-a zero average contrast study
We report on the structural properties of ionic microgel particles subjected to alternating electric fields, using small-angle neutron scattering. The experiments were performed under so-called zero average contrast conditions, which cancel the structure factor contribution to the scattered intensity, allowing us to obtain direct information on the single particle size and structure as particles a
Potential and limits of a colloid approach to protein solutions
Looking at globular proteins with the eyes of a colloid scientist has a long tradition, in fact a significant part of the early colloid literature was focused on protein solutions. However, it has also been recognized that proteins are much more complex than the typical hard sphere-like synthetic model colloids. Proteins are not perfect spheres, their interaction potentials are in general not isot
Characteristics of Particulate Emissions from Low Temperature Combustion and Renewable Fuels : Aerosol Mass Spectrometry of Refractory Carbonaceous Particles
Particulate air pollution is one of the major causes of premature death in the world, and combustion-derived soot emissions contribute strongly to the particulate pollution to which humans are exposed. Black carbon (BC) is one such emission and denotes soot with strong light absorption in the ultraviolet to infrared spectrum. Combustion can also generate brown carbon (BrC) particles, with absorpti
With increasing age at tumor diagnosis in families with cancer, cancer is limited to fewer organs
Hereditary cancer that has monogenic inheritance affects every tenth patient, on average, who is diagnosed with cancer, and it has been suggested based on twin studies, that approximately 30% of all cancer patients have a genetic predisposition to developing cancer. The author posited that familial syndromes become more organ specific with increasing age at tumour presentation to the point that ve
