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Molecular dynamic simulation of nanosized single-crystal copper beams loaded in tension at different strain rates until necking has been performed for two different crystallographic orientations, the [100]- and the [110]-orientations. The molecular dynamics freeware code LAMMPS was employed for the simulations. It was found that, at low enough strain rates, single necking was obtained for both cry
Progressive supranuclear palsy and Parkinson's disease have distinct underlying neuropathology, but both diseases affect cognitive function in addition to causing a movement disorder. They impair response inhibition and may lead to impulsivity, which can occur even in the presence of profound akinesia and rigidity. The current study examined the mechanisms of cognitive impairments underlying disin
BACKGROUND: Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington's disease is well known, improved prediction of onset would be advantageous for clinical trial design and prognostic counselling. We compared various measures for tracking progression and predicting conversion to manifest Huntington's disease.METHODS: In this prospective observa
BACKGROUND: Parkinson's disease is typically treated with oral dopamine replacement therapies; however, long-term treatment leads to motor complications and, occasionally, impulse control disorders caused by intermittent stimulation of dopamine receptors and off-target effects, respectively. We aimed to assess the safety, tolerability, and efficacy of bilateral, intrastriatal delivery of ProSavin,
BACKGROUND: Suggestive interventions such as hypnosis and therapeutic suggestions are frequently used to alleviate surgical side effects; however, the effectiveness of therapeutic suggestion intervention has not yet been systematically evaluated. In the present study, we tested the hypotheses that (1) suggestive interventions are useful for reducing postoperative side effects; (2) therapeutic sugg
Background: The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an increased risk of type 2 diabetes (T2D). We hypothesized that the association between zinc intake and T2D may be modified by the SLC30A8 genotype. Results: We carried out a pro
Background: There are currently no methods in clinical use that can detect early systemic dissemination of urothelial tumor cells. Objective: To evaluate measurement of circulating tumor cells (CTCs) as a biomarker for disseminated disease in patients with advanced bladder cancer. Design, setting, and participants: Between March 2013 and October 2015, 88 patients were prospectively included in the
Context: After an anterior cruciate ligament (ACL) injury, a majority of patients have a traumatic bone marrow lesion (BML, or bone bruise). The clinical relevance of posttraumatic lesions remains unclear. Objective: To explore the cross-sectional associations between traumatic BML volume and self-reported knee pain and symptoms among individuals within 4 weeks of ACL injury. Design: Cross-section
The adrenal-derived hormones dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are the most abundant circulating hormones and their levels decline substantially with age. DHEAS is considered an inactive precursor, which is converted into androgens and estrogens via local metabolism in peripheral target tissues. The predictive value of serum DHEAS for fracture risk is unknown. The aim of this s
BACKGROUND: Autonomic disorders of the cardiovascular system, such as orthostatic hypotension and elevated resting heart rate, predict mortality and cardiovascular events in the population. Low-energy-fractures constitute a substantial clinical problem that may represent an additional risk related to such autonomic dysfunction.AIMS: To test the association between orthostatic hypotension, resting
Measures of muscle mass, strength, and function predict risk of incident fractures, but it is not known whether this risk information is additive to that from FRAX (fracture risk assessment tool) probability. In the Osteoporotic Fractures in Men (MrOS) Study cohorts (Sweden, Hong Kong, United States), we investigated whether measures of physical performance/appendicular lean mass (ALM) by DXA pred
Mechanical force is generated within skeletal muscle cells by contraction of specialized myofibrillar proteins. This paper explores how the contractile force generated at the sarcomeres within an individual muscle fiber is transferred through the connective tissue to move the bones. The initial key point for transfer of the contractile force is the muscle cell membrane (sarcolemma) where force is
Popular Abstract in Swedish Esofagektomi (kirurgiskt avlägsnande av matstrupen) är ett omfattande ingrepp som främst utförs pga cancer, men som även utförs vid vissa godartade sjukdomar. Matstrupen sträcker sig från svalget, via bakre delen av bröstkorgen ned till övre delen av buken. Det anatomiska läget gör att man ur kirurgisk synpunkt oftast måste avlägsna matstrupen via en kombination av inciIn a prospective randomised study following oesophagectomy and gastric tube reconstruction patients with hand-sutured neck anastomoses were compared with patients with circular stapled chest anastomoses. The two groups had equal rates of anastomotic or conduit leaks of 7.3 % (3/41) and 7.1 % (3/42) and of benign anastomotic strictures of 19.5 % (8/41) and 28.6 % (12/42). Another prospective random
Purpose: We measured concentrations of human glandular kallikrein 2 (hK2), total prostate specific antigen (tPSA), free PSA (fPSA) and percent fPSA to evaluate their relationship to total prostate gland volume, benign prostatic hyperplasia (BPH) volume, total prostate cancer (PCa) volume (CaVol) and the volume of Gleason grades 4/5 cancer (CaVolG14) in the serum of 256 patients with PCa undergoing
OBJECTIVES: To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata). DESIGN: Data from two international, double blind, placebo controlled, randomised efficacy trials of quadrivalent HPV vaccine (protocol 013 (FUTURE I) and protocol 015 (F
Microsoft Word - H-guide, september, 2016.docx 1 Guide för handledning och examination av självständigt arbete (uppsats) vid Socialhögskolan, Lunds universitet Mikael Sandgren Oktober 2016 2 Förord Jag har tagit över revideringen av handledarguiden efter Marcus Knutagårds löpande revideringar av Katarina Jacobssons arbete med texten som bygger på hennes återkommande möten med examinatorer och hand
https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2023-03/handledarguide%20-%20oktober%202016.pdf - 2026-05-06
FINAL SIMM32 180917.pdf SAKmnA0 GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Quantitative Methods: Multivariate Analysis For an always up-to-date online version, please visit the course site (check regularly for updates) SIMM32 Autumn 2018, version 1.0 Welcome! SIMM32 Welcome to the Autumn term’s course Quantitative Methods: Multivariate Analysis The aim of this course is for s
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_simm32_180917.pdf - 2026-05-06
FINAL SIMM32 181112.pdf SAKmnA0 GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Quantitative Methods: Multivariate Analysis For an always up-to-date online version, please visit the course site (check regularly for updates) SIMM32 Autumn 2018, version 1.0 Welcome! SIMM32 Welcome to the Autumn term’s course Quantitative Methods: Multivariate Analysis The aim of this course is for s
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_simm32_181112.pdf - 2026-05-06
SED Report 2017 Destinations This publication should be cited as: International Institute for Industrial Environmental Economics [IIIEE]. 2017. Rays of Sunshine: Tales of Sustainable Transitions. Lund: IIIEE ISBN: 978-91-87357-28-2 Alentejo, Portugal Berlin, Germany Zabrze, Poland Wonsho, Ethiopia Deva, RomaniaNakuru, Kenya Content Food for Thought: Developing Horticulture Sustainably in Nakuru Co
https://www.iiiee.lu.se/sites/iiiee.lu.se/files/final_report_sed_emp_rays_of_sunshine_2017_0.pdf - 2026-05-06
LUDC-IRC Postdoctoral Program 2020 – Project 6 LUDC-IRC Postdoctoral Program 2020 – Project 6 The role of hormone sensitive lipase in brain function PI: Cecilia Holm Co-PI: Joao Duarte Purpose and aims Hypothalamic dysfunction has been suggested to precipitate the development of obesity and metabolic syndrome. On the other hand, complications deriving from unhealthy lifestyles and obesity impact t
https://www.ludc.lu.se/sites/ludc.lu.se/files/holm_project_6.pdf - 2026-05-06
