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BackgroundInflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making. We therefore aimed to investigate the plasma levels of vascular and inflammatory proteins, and their associations with invasive hemodynamics in adva

Background: A juxtarenal abdominal aortic aneurysm is defined as a short (less than 4mm) or no-neck aneurysm, which is often treated with open or complex endovascular repair. The evidence to support the best treatment strategy is scarce. The aim of this study was to assess the short- and mid-term outcomes of elective open surgical repair or fenestrated endovascular aneurysm repair for juxtarenal a

Objective: To analyze the outcomes of urgent/emergent endovascular aortic repair of patients with free/contained ruptured thoracoabdominal aortic aneurysms (rTAAA). Background: Endovascular repair of rTAAA has been scarcely described in emergent setting. Methods: An international multicenter retrospective observational study (ClinicalTrials.govID:NCT05956873) from January 2015 to January 2023 in 6

Background: Rare variants of the triggering receptor expressed on myeloid cell 2 (TREM2) gene are strong risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown what the effect of TREM2 variants is on the AD phenotype. Methods: Here we studied a full range of clinical and biomarker measures in a large cohort of TREM2 variant carr

Background: Keeping the umbilical cord intact the first minutes after delivery is beneficial for both term and preterm infants. However, this may be challenging in caesarean sections (CS) due to lack of mobile resuscitation equipment, maintenance of sterility or concern for excessive maternal blood loss. The objective of this study was to develop and pilot-test extra-uterine placental transfusion

Background: MR-generated acoustic noise may be particularly concerning at 7-Tesla (T) systems. Noise levels can be reduced by altering gradient output using software optimization. However, such alterations might influence image quality or prolong scan times, and these optimizations have not been well characterized. Purpose: To evaluate image quality, sound pressure levels (SPLs), and perceived noi

The Central Scandinavian Dolerite Group (CSDG) occurs in five separate complexes in central Sweden and SW Finland. U-Pb baddeleyite ages of dolerite dikes and sills fall into three age intervals: 1264-1271 (the Dalarna complex), 1256-1259 (the Vdsterbotten-Ulvo-Satakunta complexes) and similar to 1247 Ma (the Jamtland complex). Timing and spatial distribution of CSDG are unlike expressions of the

OBJECTIVES: To evaluate the efficacy, safety, and tolerability of a new, once-daily extended-release (ER) formulation of tolterodine in treating overactive bladder in older (greater than or equal to65) and younger (<65) patients. DESIGN: A 12-week double-blind, placebo-controlled clinical trial. SETTING: An international study conducted at 167 medical centers. PARTICIPANTS: One thousand fifteen pa

Between 1992 and 2004, 1,140 children (1 to < 15 years) were diagnosed with B-cell precursor acute lymphoblastic leukemia (ALL) in the Nordic countries. Of these, 288 (25%) were positive for t(12; 21)(p 13;q22) [ETV6/RUNXI]. G-banding analyses were successful in 245 (85%); 43 (15%) were karyotypic failures. The modal chromosome numbers, incidence, types, and numbers of additional abnormalities, ge

Studies, mainly from the UK, show that many farmland birds have declined as a result of recent agricultural intensification. We tested this idea by analysing farmland bird population trends in Sweden, a country displaying less dramatic agricultural changes and less intensive agriculture. Specifically we investigated whether (i) farmland specialists have declined more than generalists, (ii) populat

A knee injury with anterior cruciate ligament (ACL) rupture may cause deficits in proprioception, increased laxity and decreased muscle strength. Although it may be common knowledge that these factors affect knee function, only a few studies have been performed where this has been investigated in the clinical situation, and the results are not conclusive. The purpose of this study was therefore to

Aims/hypothesis Genetic and epidemiological studies suggest an association between gestational diabetes mellitus and type 2 diabetes. Both are polygenic multifactorial disorders characterised by beta cell dysfunction and insulin resistance. Our aim was to investigate whether common genetic variants that have previously been associated with type 2 diabetes or related phenotypes would also confer ri

Popular Abstract in Swedish I Sverige analyseras omkring 40 000 DNA-prover från brottsplatser varje år. DNA-profilerna jämförs mot DNA-profiler från misstänkta personer och kan på så vis användas för att knyta en person till ett brott. Alla typer av kroppsvävnader kan analyseras, såsom blod, saliv och hudceller. Vanliga bevismaterial är cigarettfimpar, flaskor, burkar och kläder. De material som cDNA evidence, linking perpetrators to crime scenes, is central to many legal proceedings. However, crime scene samples often contain extraneous substances that may interfere with the PCR-based forensic analysis, resulting in partial or negative DNA profiles. Extensive DNA purification may remove inhibitors, but involves the risk of DNA loss. In this work, pre-PCR processing was applied to improve

Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying re

Background: The aim of this study was to examine in elderly men a relationship between depressive symptoms, peripheral vascular disease and cerebral blood flow (CBF). Methods: Population-based cohort study started with an examination of 809 men at age 55, followed by the first (age 68ys) and second follow up (age 82ys). 128 survivors were examined at age 82 with Tc-99m-HMPAO-SPECT to estimate CBF,

Intermittent Parathyroid Hormone (PTH)((1-34)) has an established place in osteoporosis treatment, but also shows promising results in models of bone repair. Previous studies have been dominated by closed fracture models, where union is certain. One of the major clinical needs for anabolic therapies is the treatment of open and high energy fractures at risk of non-union. In the present study we th

Magisterexamen kan du få om du tidigare har en kandidatexamen om minst 180 högskolepoäng (hp) eller motsvarande, och läser ytterligare 60 hp varav minst 30 består av en fördjupning inom huvudområdet. Inom huvudområdet ska det finnas ett självständigt examensarbete om minst 15 hp. Minst 75 % av kurserna måste vara på avancerad nivå.Specifika kurskrav hittar du i programmens utbildningsplaner.Sök bl

https://www.lu.se/student/examen-och-karriar/examen/examina/magisterexamen-1-ar - 2026-05-08

OBJECTIVE: To determine what constitutes normal cervical changes during the second half of pregnancy in parous women delivering at term. DESIGN: The study comprises 21 healthy, pregnant parous women who all gave birth at term. They were examined with transvaginal ultrasound every two weeks from 24 gestational weeks until delivery. Cervical length and width were measured. The inner cervical os was

The study is based on monitoring data on the seasonal variation during four (1996-1999) vegetation periods, as well as long-term summer data on submerged vegetation, nutrients, light, phyto-plankton and zooplankton in Lake Krankesjon, a shallow, calcium-rich, moderately eutrophic take in southern Sweden. The lake has been in the clear water state with abundant submerged vegetation since the end of