Search results

Cerebral ischemia that develops after subarachnoid hemorrhage (SAH) carries high morbidity and mortality. Inflammatory mediators are involved in the development of cerebral ischemia through activation of the mitogen-activated protein kinase pathway. We hypothesized that blockade of the MAPkinase/ERK (MEK)/extracellular signal-regulated kinase (ERK) pathway upstream with a specific raf inhibitor wo

Safety at INES Safety at MGeo DEPARTMENT OF EARTH AND ENVIRONMENTAL SCIENCES | JANUARY 2026 2 Safety work and regulations at MGeo This is a general document about commons risks at the Department of Earth and Environmental Sciences and the safety work we do to minimise identified risks. All staff and students are asked to read this and follow the regulations.This is necessary in order for you to be

https://www.mgeo.lu.se/internal/sites/mgeo.lu.se.internal/files/2026-03/Safety%20at%20MGeo%20v1.pdf - 2026-05-11

Aircraft observations of precipitating clouds with cloud top temperatures higher than -38°C have revealed that Secondary Ice Production (SIP) is responsible for presence of majority of ice particles. One such SIP mechanism is fragmentation via collisions between ice particles. The central theme of this study is to understand the dependencies of this SIP mechanism and improve its existing numerical

This thesis explores the implementation and acceptability of blanket (population-wide coverage of active case finding and prevention) Post-Exposure Prophylaxis (PEP) as a preventive measure for leprosy transmission in the Achham district of Sudurpaschim (Far-west) Province in Nepal. Leprosy remains a significant public health concern in Nepal, with persistent challenges in prevention and control e

Given the current societal and political developments in Germany, the visibility and integration of-marginalized is essential to ensure their inclusion in mainstream society. One way of encouraging-contact between majority and marginalized groups is through building social networks, of which-informal and nonformal educational activities play an important part. This thesis examines the-experience o

PEDS_20162848.indd ARTICLEPEDIATRICS Volume 139 , number 3 , March 2017 :e 20162848 Psychological Manifestations of Celiac Disease Autoimmunity in Young Children Laura B. Smith, PhD, a Kristian F. Lynch, PhD, b Kalle Kurppa, MD, PhD, c Sibylle Koletzko, MD, PhD, d Jeffrey Krischer, PhD, a Edwin Liu, MD, e Suzanne Bennett Johnson, PhD, f Daniel Agardh, MD, PhD, g The TEDDY study group abstractBACKG

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/65%2001252019_679_065_MP124_Smith_Pediatrics_2017.pdf - 2026-05-11

Kursguide - Course Syllabus Fastställande Kursplanen är fastställd av Institutionsstyrelsen vid Teaterhögskolan i Malmö 2021-10- 27 att gälla från och med 2022-06-06, vårterminen 2022. Allmänna uppgifter Kursen ges som en fristående kurs. Den kan normalt ingå i såväl en grundläggande som en konstnärlig examen på grundnivå.  Undervisningsspråk: Svenska Kursens mål Studenten ska  Kunskap och förståe

https://www.thm.lu.se/sites/thm.lu.se/files/2022-06/SK%C3%85B23,%20Entrepren%C3%B6rskap%20f%C3%B6r%20scenkonstn%C3%A4rer%20inom%20musik%20och%20teater.pdf - 2026-05-11

Detecting potential outliers in longitudinal data with time-dependent covariates ARTICLE Detecting potential outliers in longitudinal data with time-dependent covariates Lazarus K. Mramba 1✉, Xiang Liu1, Kristian F. Lynch1, Jimin Yang 1, Carin Andrén Aronsson 2,3, Sandra Hummel4, Jill M. Norris5, Suvi M. Virtanen6,7,8,9, Leena Hakola8,9, Ulla M. Uusitalo 1 and Jeffrey P. Krischer1 © The Author(s),

https://www.teddy.lu.se/sites/teddy.lu.se/files/2024-04/162_MP286_Mramba_EJCN_2024.pdf - 2026-05-11

BACKGROUND: De novo oligometastatic prostate cancer (omPCa) on prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is a new disease entity and its optimal management remains unknown. OBJECTIVE: To analyze the outcomes of patients treated with cytoreductive radical prostatectomy (cRP) for omPCa on PSMA-PET. DESIGN, SETTING, AND PARTICIPANTS: Overall, 116 patients treated wi

Fat-soluble vitamin D is an essential bioactive compound important for human health. Insufficient vitamin D levels can result not only in bone disease but also in other disorders, such as cancer, metabolic disorders, and diseases related to poor immune function. The current methods commonly used for vitamin D analysis are often applied to determine the levels of the most abundant metabolite in pla

Background: Retrospective comparative studies suggest a survival benefit after complete local treatment of recurrence (LTR) in renal cell carcinoma (RCC), which may be largely due to an indication bias. Objective: To determine the role of LTR in a homogeneous population characterised by limited and potentially resectable recurrence. Design, setting, and participants: RECUR is a protocol-based mult

Background: The number of pregnant women with congenital heart disease (CHD) is rising, and the disease poses increased risks of cardiovascular and obstetric complications during pregnancy, potentially impacting breastfeeding success. This study aimed to investigate breastfeeding in primiparous women with CHD compared to primiparous women without CHD, and to examine potential hindering factors for

BACKGROUND: Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 positively affect the fecal bacteriome in children with celiac disease autoimmunity after 6 months of supplementation. The aim of the present investigation was to study the effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 on the single-cell parasitome, with a primary focus

Introduction: The impact of exposure to endemic infections on basal immunity and susceptibility to HIV-1 acquisition remains uncertain. We hypothesized that exposure to infections such as cytomegalovirus (CMV), malaria and sexually transmitted infections (STIs) in high-risk individuals may modulate immunity and subsequently increase susceptibility to HIV-1 acquisition. Methods: A case-control stud

Purpose: Glaucoma is a heterogeneous group of optic neuropathies that potentially may be associated with other cerebral neurodegenerative processes leading to dementia. However, prior studies have been inconsistent. We examined dementia risks after glaucoma diagnosis in a large population-based cohort. Design: National matched cohort study. Participants: A total of 324 730 persons diagnosed with g

IMPORTANCE: The introduction of solid or semisolid foods alongside breast milk plays a vital role in meeting nutritional requirements during early childhood, which is crucial for child growth and development. Understanding the prevalence of zero-food children (defined for research purposes as children aged 6 to 23 months who did not consume animal milk, formula, or solid or semisolid food during t

BACKGROUND: Accurate risk stratification in older adults presenting to the emergency department (ED) is essential but challenging due to atypical presentations and age-related physiological changes. While vital signs are central to triage, their predictive value for short-term mortality in this population remains unclear. This study aimed to explore the association between initial vital signs and

Background: Opioid use disorder is a chronic disorder with a high risk of overdose-related morbidity and mortality where a large proportion of these can be averted by timely administration of the antidote naloxone. For naloxone to be present when and where overdoses occur, broad-scale overdose education and naloxone distribution (OEND) must be established. A regional naloxone program was implement

BACKGROUND: Prior research has established a positive association between the single-measured triglyceride-glucose (TyG) index and hypertension. Nevertheless, longitudinal studies addressing the enduring impact of TyG index on incident hypertension are lacking. This study sought to explore the association between cumulative TyG index (cum-TyG) and incident hypertension, especially obesity-related

AIMS: Metformin has hitherto not been proven superior to other type 2 diabetes (T2D) medications for the prevention of organ complications. The aim of this study is to report baseline data and blinded interim analyses in the register-based randomised clinical trial (RRCT) SMARTEST, which compares metformin and the SGLT2 inhibitor dapagliflozin in early T2D. We also present learnings from the novel