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Molecular Structure and Packing of Platinum(II) Complexes with S-donor Ligands in the Solid State An X-ray Crystallographic Study

Popular Abstract in Swedish All materia består av atomer. Avhandlingen du just nu läser är uppbyggd av atomer; till och med du själv är uppbyggd av atomer. En kemist är intresserad av vilka atomer som hänger ihop för att bilda molekyler och hur dessa molekyler kan sammanfogas till fasta material. Man kan likna det vid att molekylerna är en byggsten som då de sammanfogas bildar en byggnadskonstruktHow do molecules arrange themselves in a crystal? It is today not possible to definite predict the three-dimensional packing arrangement of molecules in the crystalline solid state. The aim of the work presented in this thesis has been to gain more knowledge of what principles that govern molecular packing. Platinum(II) complexes have been chosen as model system since these compounds are stable,

Epidemiology and clinical manifestations of Lyme borreliosis.

Popular Abstract in Swedish Det har nu gått 20 år sedan ett utbrott av ledinflammation (arthrit), i Connecticut, USA, satte forskarna på spåret till den sjukdomsbild som vi idag kallar fästingöverförd borreliainfektion och det är snart 15 år sedan man lyckades isolera bakterien som orsakar sjukdomen, Borrelia burgdorferi. Symptomen på sjukdomen har visserligen varit kända sedan sekelskiftet men he

Vasoactive Peptides with Angiogenesis-Regulating Activity Predict Cancer Risk in Males.

BACKGROUND: Tumor development requires angiogenesis, and antiangiogenesis has been introduced in the treatment of cancer patients; however, how the cardiovascular phenotype correlates with cancer risk remains ill-defined. Here, we hypothesized that vasoactive peptides previously implicated in angiogenesis regulation predict long-term cancer risk.METHODS: We measured midregional proatrial natriuret

Undisturbed theatre dressing during the first postoperative week. A benefit in the treatment by external fixation: a cohort study.

In the literature, there are several different suggestions as to when the first postoperative pin-site care should be carried out to best prevent pin-site infections during the treatment by external fixation. In a cohort study, we compared the use of antibiotics and complications in patients where the theatre dressing was changed during the first postoperative week with patients where the theatre

Incidence and characteristics of distal radius fractures in a southern Swedish region

BACKGROUND: The incidence of distal radius fracture has increased substantially during the last 50 years according to several studies that estimated the overall incidence in various general populations. The incidence of fracture classified according to severity has not been well documented. The aim of this population-based study was to estimate the overall and type-specific incidence rates of dist

X-Stop Versus Decompressive Surgery For Lumbar Neurogenic Intermittent Claudication: A Randomized Controlled Trial With 2 Years Follow-Up.

ABSTRACT: Study Design. Prospective randomized controlled study.Objective. To compare the outcome of indirect decompression by means of the X-Stop implant to conventional decompression in patients with neurogenic intermittent claudication due to lumbar spinal stenosis.Summary of Background Data. Decompression is the golden standard for lumbar spinal stenosis nowadays but afflicted with complicatio

Effect of Type 2 Diabetes Predisposing Genetic Variants on Colorectal Cancer Risk.

Background: The link between colorectal cancer (CRC) and type 2 diabetes mellitus (T2D) has been extensively studied. Although it is commonly accepted that T2D is a risk factor for CRC, the underlying mechanisms are still poorly understood. Research Design and Methods:Given that the genetic background contributes to both traits, it is conceivable that genetic variants associated with T2D may also

Validation of the Lund-Malmö, Chronic Kidney Disease Epidemiology (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) equations to estimate glomerular filtration rate in a large Swedish clinical population.

Abstract Objective. The aim of this study was to validate externally the Swedish Lund-Malmö revised creatinine-based glomerular filtration rate (GFR) equations (LM Revised) in a Swedish cohort in comparison with the North American Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology (CKD-EPI) equations. Material and methods. The study included 1397 examinations [med

Inaccuracy of GFR predictions by plasma cystatin C in patients without kidney dysfunction and in advanced kidney disease.

BACKGROUND: In clinical practice there is need for a simple and reliable test for determination of impaired renal function. With reductions in GFR, the plasma cystatin C concentration (C, mg/l) will increase earlier than serum creatinine, and it is generally agreed that plasma cystatin C is only little affected by body weight, age or sex. However, some reports indicate that cystatin C may be influ

Activated protein C-protein C inhibitor complex: a new biological marker for aortic aneurysms.

Objective: The concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI) is a measure of thrombin generation. We studied whether it can provide information useful for the diagnosis and treatment of arterial vascular disease. Methods: Blood was obtained from 429 vascular patients admitted consecutively during September 2004 to March 2005. The APC-PCI complex was m

Konturer av ett kvinnligt fält : Om missbrukande kvinnors möten i familjeliv och behandling

Popular Abstract in Swedish Missbrukande kvinnor och mammor har ofta fördömts av samhället och av människor i sin omgivning. De har setts som ansvarslösa kvinnor och olämpliga mammor utifrån en samhällssyn, att barn och missbruk inte går ihop. De livshistoriska intervjuerna med missbrukande kvinnor och mammor, som avhandlingen bygger på visar, att kvinnorna både vill vara respektabla och ta väl haThe aim of the dissertation is to describe the conditions under which substance abusing women live with regard to their families, the substance abuse and treatment. The interaction between the substance abusing women and the institutional expectations is analysed from gender and class perspective. The dissertation is based on interviews with two groups of substance abusing women: 12 mothers, livin

Fibrillatory rate response to candesartan in persistent atrial fibrillation.

Introduction Angiotensin-receptor blockers may exert favourable anti-arrhythmic effects in atrial fibrillation (AF), but their mechanisms are not fully understood. In this study, we tested the hypotheses that (i) candesartan reduces atrial fibrillatory rate and (ii) fibrillatory rate and its response to candesartan are related with the outcome of cardioversion. For this purpose, a post hoc subanal

Iliocaval vein stenting: Long term survey of postthrombotic symptoms and working capacity.

To evaluate the long term effect on lower extremity function and working capacity after stenting of iliocaval vein segments for acute deep venous thrombosis (DVT) or chronic venous occlusive disease. During a 14 year period from November 1994 to October 2008, 114 patients with median age 36 (interquartile range [IQR], 27-48) years, 72 (63%) women, 72 (63%) with hypercoagulable disorders, with acut

Alignment and orientation of Nanowires in a thin film under the influence of an electric field

Produktion av en nanotrådssolcell För att ta itu med miljöpåverkan från växthusgaser krävs en övergång till förnyelsebara energikällor. Ett exempel på en sådan källa är nanotrådssolceller. I mitt examensarbete har jag undersökt hur nanotrådar kan arrangeras på sådant sätt som krävs för att kunna omvandla solljuset till elektricitet. Global uppvärmning är ett hot som till stor del orsakas av utslThe demand for cheaper and more efficient solar cells is high. One way to decrease cost of material, while maintaining a high degree of efficiency, is to take advantage of nanomaterials. A thin film containing pn-junction nanowires can convert light with an efficiency comparable to traditional planar cells, while using a fraction of the material, and thus reduce costs. At the company Sol Voltaics

New Evidence for Selective Reporting in Climate Change Science

Populärvetenskaplig sammanfattning: Är klimatforskningen skev? En central fråga är om vi kan lita på att vetenskapliga tidskrifter återger en rättvis bild av aktuella forskningsresultat? Dessutom bör vi fråga oss hur rapporteringen påverkas då betydande händelser sker inom vetenskapsvärlden. I november 2007 och senare 2009 skedde två viktiga företeelser inom klimatforskningen som potentiellt kanAbstract The declaration of a scientific consensus concerning anthropogenic causes for climate change by the IPCC in their fourth assessment report (AR4), published in 2007, initiated a heated debate. During this debate, experts within the IPCC were accused of selective reporting and the AR4 got strong source criticism by politicians, stakeholders and climate skeptics in general. The debate furth

Evaluation of overheating risks and passive cooling measures in low energy Swedish dwellings

Overheating in buildings is becoming a major concern and cause for various health issues. Existing research and previous studies on the issue were examined to acquire relevant information about the definition of overheating, its possible causes, and the heath impacts it could have on human health. The review included data on the current status of thermal comfort and overheating regulations in Swed

Vem kontrollerar kontrollanten? - En kritisk granskning av en utökning av preventiva tvångsmedel utifrån ett rättssäkerhetsperspektiv

Den allvarliga brottsligheten som begås av kriminella nätverk har ökat drastiskt under de senaste åren. Skjutningar och sprängningar har blivit alltmer förekommande och diskuteras frekvent i medier och politiska debatter. Hur man ska komma till rätta med problemet är en angelägen fråga. Ett av förslagen, för att ge de brottsutredande myndigheterna effektivare verktyg för att förhindra denna typ avSerious crimes committed by criminal networks have increased over the last couple of years. Shootings and explosions have become more common and are frequently discussed in media and political debates. How to solve this problem is an important question and a proposal that has been suggested, with the purpose to give criminal investigation authorities more effective tools to prevent these serious c

Det som krävs för att Lunds Klimatallians ska kunna utveckla sina medlemmars hållbarhetsarbete

Lunds Klimatallians har ambitioner att hjälpa sina medlemmar arbeta mot en hållbar utveckling och letar efter nya metoder för att förbättra sin insats. Lunds Klimatallians är en organisation som startades i initiativ av Lund Kommuns miljöstrategiska enhet i syfte att bidra till Sveriges genomförande av FN:s klimatmål. Målen ska leda världen mot en hållbar utveckling men i dagsläget finns hållbarheLund's Climate Alliance was initiated 2010 by the municipality of Lund, in southern Sweden, to support local climate adaptation and mitigation efforts. The purpose of this paper is to investigate what each member of Lund's Climate Alliance believes will be necessary to realize sustainability goals particular to their organization in the future. The study thereby points to new topics, activ

Investigation of possible approaches for consequential electricity markets in ecoinvent

Version 3 av ecoinvent är den första databasen att erbjuda möjligheten att koppla samman livscykelinventeringar (LCI) utefter olika länkningsalgoritmer. Genom dessa länkningsalgoritmer tar ecoinvent nu fram bakgrundslivscykelinventeringar med både medeldata och långsiktig marginaldata (t.ex. över elmarknader i olika länder). Idealt sett representerar långsiktig marginaldata över elmarknader den ytVersion 3 of the ecoinvent database is the first background database to offer the possibility to link life cycle inventories (LCI) according to different linking algorithms. Using those algorithms, ecoinvent now provides both average and long-term, marginal background LCI data, (e.g. for electricity markets for different countries). Long-term, marginal data for electricity markets ideally represen

Direct hollow fiber liquid phase membrane extraction and LC-MS/MS determination of non-steroidal anti-inflammatory drugs in fish

Popular summary The fate of non-steroidal anti-inflammatory drugs The knowledge about distribution of drugs between sewage sludge, water phases and water living organisms is vital for predictions of the fate and transport routes of toxic substances to the environment. And the distribution of drugs in the environment can be used as a base for risk assessments and it also can be used to define desir