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Cerclage fixation without K-wires is associated with fewer complications and reoperations compared with tension band wiring in stable displaced olecranon fractures in elderly patients

Introduction: Tension band wiring of olecranon fractures has high reported rates of complications and reoperations. We aimed to compare classic tension band wiring to cerclage fixation without K-wires in the treatment of displaced olecranon fractures in elderly patients. The primary outcome was reoperation. Secondary outcomes included complications and patient reported outcomes. Outcomes following

Seasonality of ventricular fibrillation at first myocardial infarction and association with viral exposure

Aims To investigate seasonality and association of increased enterovirus and influenza activity in the community with ventricular fibrillation (VF) risk during first ST-elevation myocardial infarction (STEMI). Methods This study comprised all consecutive patients with first STEMI (n = 4,659; aged 18–80 years) admitted to the invasive catheterization laboratory between 2010–2016, at Copenhagen Univ

Accuracy of NIH Stroke Scale for diagnosing aphasia

Objectives: The National Institutes of Health Stroke Scale (NIHSS) has not been validated to diagnose aphasia in the stroke population. We therefore examined the diagnostic accuracy of NIHSS for detecting aphasia in acute ischemic stroke. Methods: Consecutive patients with acute first-ever ischemic stroke were included prospectively in Lund Stroke Register Study at Skåne University Hospital, Swede

Risk of late health effects after soft-tissue sarcomas in childhood–a population-based cohort study within the Adult Life after Childhood Cancer in Scandinavia research programme

Background: In the 1960s only 1/3 of children with soft-tissue sarcomas survived, however with improved treatments survival today has reached 70%. Given the previous poor survival and the rarity of soft-tissue sarcomas, the risk of somatic late effects in a large cohort of Nordic soft-tissue sarcoma survivors has not yet been assessed. Methods: In this population-based cohort study we identified 9

Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death : an analysis of 712 cases

Background: Lemierre syndrome is characterized by head/neck vein thrombosis and septic embolism usually complicating an acute oropharyngeal bacterial infection in adolescents and young adults. We described the course of Lemierre syndrome in the contemporary era. Methods: In our individual-level analysis of 712 patients (2000–2017), we included cases described as Lemierre syndrome if these criteria

Anti-neutrophil cytoplasmic antibodies predate symptom onset of ANCA-associated vasculitis. A case-control study

Objectives: Anti-neutrophil cytoplasmic autoantibodies [ANCA) are important for diagnosis of ANCA-associated vasculitides (AAV). The timing of antibody development is not well established. To investigate the development of proteinase 3 (PR3)- and myeloperoxidase (MPO)-ANCA, blood samples collected before onset of symptoms of AAV were analysed. Methods: To identify AAV patients with blood samples p

Soluble CD40 receptor is a biomarker of the burden of carotid artery atherosclerosis in subjects at high cardiovascular risk

BACKGROUND AND AIMS: The severity of the atherosclerotic burden is hardly quantifiable in subjects at high cardiovascular (CV) risk under intensive pharmacological therapy. Several molecules have been proposed as circulating biomarkers of atherosclerosis, but none has emerged as clinically meaningful.METHODS: Circulating proteins involved in inflammation, plaque remodeling, smooth muscle cell migr

The power of genetic diversity in genome-wide association studies of lipids

Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use1. Despite advances in prevention and treatment, in particular through reducing low-density lipoprotein cholesterol levels2, heart disease remains the leading cause of death worldwide3. Genome-wideassociation studies (GWAS) of bloo

Tuberculosis treatment outcome and predictors in africa : A systematic review and meta-analysis

This review aimed to summarize and estimate the TB treatment success rate and factors associated with unsuccessful TB treatment outcomes in Africa. Potentially eligible primary studies were retrieved from PubMed and Google Scholar. The risk of bias and quality of studies was assessed using The Joanna Briggs Institute’s (JBI) appraisal criteria, while heterogeneity across studies was assessed using

Comparative risk of suicide by specific substance use disorders : A national cohort study

Substance use disorders (SUDs) are important risk factors for suicide, yet little is known about how suicide risks vary by specific SUDs. We examined these risks for the first time in a large general population to facilitate comparisons across SUDs. A national cohort study was conducted of all 6,947,191 adults in Sweden. SUDs (opioid, sedative/hypnotic, hallucinogen, cannabis, amphetamine, cocaine

Education

We offer a range of basic level courses within biomedical technology, e.g. about biomechanics, sensors, ultrasound, measurement techology, signal processing, neural interfaces. Most of these are conducted in Canvas. Some of the basic level courses are also given as PhD courses. We offer Master's theses work within two main areas: Biomedical Technology, NMEN 01, and Electrical Measurements, BME 05.

https://www.bme.lth.se/en/education - 2026-05-27

Thiopurines and intrahepatic cholestasis of pregnancy in systemic lupus erythematosus and inflammatory bowel disease pregnancies

Objectives: To examine the effects of thiopurine exposure during pregnancy on intrahepatic cholestasis of pregnancy (ICP) in systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) pregnancies using nationwide data from Swedish healthcare registers. Methods: This register-based cohort study included all singleton pregnancies with prevalent SLE or IBD in Sweden, 2007-2022. Exposure

Feasibility of an interpreter-mediated neuropsychological test battery for trauma-affected refugees

Background: Cognitive impairment in trauma-affected refugees is often unassessed due to the absence of suitable cross-cultural neuropsychological measures, the high prevalence of psychiatric symptoms, and the need for interpreter mediation. This poses both a clinical challenge and a health inequality for trauma-affected refugees who are left without access to much needed rehabilitation. Untreated

Direct letters to relatives at risk of hereditary cancer—a randomised trial on healthcare-assisted versus family-mediated risk disclosure

Observational studies suggest that direct contact from healthcare to at-risk relatives may increase genetic counselling (GC) uptake as compared to family-mediated risk disclosure, but randomised controlled trials (RCTs) are lacking. This study assessed whether the offer of direct letters to relatives at risk of hereditary breast and ovarian cancer (HBOC) or Lynch syndrome increases GC uptake compa

Differences Between Sweden and Greece in Joint Outcomes Assessed by Ultrasound in Adolescents With Severe Haemophilia on Prophylaxis : Data From the PedNet Registry

Introduction: Different strategies in prophylaxis for haemophilia among countries may affect long-term outcome. Aim: The aim of this study is to compare joint health in persons with severe haemophilia (PwSH) between Sweden and Greece, based on different approaches on prophylaxis initiation and management. Methods: Data were extracted from the PedNet Registry, which collects patient data prospectiv

Publishing a doctoral thesis in full text

Publishing a doctoral thesis in full text will increase its visibility and use. It is important to know which copyright rules apply. Below are some guidelines for each type of doctoral thesis. Visibility of the doctoral thesisIf you publish your doctoral thesis electronically, it will not only be indexed and made searchable in Google. It will also be listed in the European doctoral theses database

https://www.lub.lu.se/en/services-and-support/publishing-and-registering/registeringpublishing-lucris-researchers/doctoral-theses/publishing-doctoral-thesis-full-text - 2026-05-27

Education

Undergraduate educationThe teaching at the Department of Technology and Society is firmly established in both research and the professional work of public and private companies.The different divisions have excellence in their respective fields and provide courses within the engineering programmes at LTH and the Bachelor of Science programmes in engineering at Campus Helsingborg on subjects such as

https://www.tos.lth.se/en/education - 2026-05-27

154

DC230417_proof.pdf HLA Genotype and Probiotics Modify the Association Between Timing of Solid Food Introduction and Islet Autoimmunity in the TEDDY Study Ulla Uusitalo, Lazarus K. Mramba, Carin Andren Aronsson, Kendra Vehik, Jimin Yang, Sandra Hummel, Åke Lernmark, Marian Rewers, William Hagopian, Richard McIndoe, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jeffrey P. Krischer, Suvi M. Virtan

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-12/154.pdf - 2026-05-27

Peripheral Serotonin and CYP2D6: Candidate Biomarkers of Antidepressant Treatment Response

Background and aimMany patients with depressive disorders do not improve with first-line treatment with selective serotonin inhibitors (SSRIs). Adverse drug reactions (ADRs) are common. However, there are no reliable methods to predict treatment response.The general aim of this thesis was to investigate the role of peripheral serotonin and the polymorphic CYP2D6 gene as potential biomarkers of tre