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BACKGROUND: Children with autism spectrum disorder (ASD) are at increased risk of epilepsy (EP), but distinguishing epileptic seizures from ASD-associated behavior remains a clinical challenge. Although previous studies have reported changes in peripheral immune markers in adults with EP, it remains unclear whether similar immune signatures are present in pediatric patients with both ASD and EP, a

Background: Low-cost particulate matter sensors have enabled new opportunities for exposure monitoring but require evaluation before application in epidemiological studies. This study assessed the performance of the SPS30 sensor integrated into the ARMIE portable monitoring sensor-node under controlled laboratory conditions. Methods: Sensors were co-located with two comparison instruments—the opti

Traffic-related air pollution has severe implications for our health and stringent emission legislation is being enforced to traffic emissions, for example in the EU, USA, and China. With stricter emission legislation (next is EURO 7) and a rapid growth of battery electrical vehicles (BEVs) the combustion-derived pollutants emitted from the tailpipe are decreasing. However, heavier vehicles have r

Comparison of ROS production of individual particle components from traffic-related sources can inform new health policies and emissions legislation. This work aims to quantify acellular ROS production and oxidative potential (OP) of such individual particle components from combustion, brake, tire, and road wear. Particle characteristics are probed to identify source-specific markers and improve t

In the 1960s and 1970s, Third World diplomats and jurists developed a distinct understanding of the use of force in international law. Two conclusions emerged from the understanding that colonial rule had been a “permanent aggression” against their territories: Firstly, a right to self-defense against colonial domination is a necessary corollary to the right to self-determination in the face of vi

Herein, we present a case of severe immune-related adverse events (irAEs), myocarditis with myositis, and myasthenia gravis overlap syndrome (IM3OS) in a patient receiving an immune checkpoint inhibitor (ICI), as adjuvant therapy after surgery for muscle-invasive bladder cancer. An 80-year-old woman who had undergone a total cystectomy for bladder cancer presented with ptosis, diplopia, and paraly

The Circular Economy (CE) concept is widely promoted as a pathway to sustainability, yet its practical realization can appear to be challenging and unclear due to divergent definitions, interpretations and understanding about the implications and goals of a realized CE. Addressing this gap, this study develops the Circular Economy Loop Strategies (CELS) Framework, a synthesizing foundational model

This chapter reviews the historical development of the regulation of waste and chemicals in both international law and European Union (EU) law after the 1972 Stockholm Conference as well as some of the subsequent trends and themes. It also highlights the relevant interactions between EU and international law on these issues. The chapter ends with a discussion of how the regulatory frameworks relat

Scapolite-bearing orthogneisses underlying the Proterozoic Varena Iron Ore Deposit, eastern Lithuania, the western East European Craton, represent the development of a sodic alteration zone. Scapolite chemistry records fluid salinity increase with temperature, reaching its maximum at temperatures of ∼750 °C. Fluid-mineral reactions controlled the fluid KCl/NaCl ratio, enabling partial melting at p

Women are born with thousands of ovarian follicles, yet less than 1% will ovulate a mature oocyte. What distinguishes the 99% of follicles destined for demise from the rare 1% that succeed? Here, we leveraged a unique clinical opportunity, paired follicular fluid samples from small antral follicles containing either a viable or an atretic oocyte within the same patients, to uncover the proteomic d

This paper has its starting point with the discrepancy between the ICPD Plan of Action and the Millennium Development Goals with regards to their separate emphasis on the importance of family planning services as a reproductive health component. The population problem can be looked upon from various theoretical schools. This paper examines the sharply contrasting views of economists, on the one ha

OBJECTIVES: The Apollo study was designed to support the clinical performance verification of the adjusted cutoffs of the Elecsys® β-Amyloid(1-42) (Aβ42) cerebrospinal fluid (CSF) II, β-Amyloid(1-40) (Aβ40) CSF, Phospho-Tau (181P) (pTau) CSF and Total-Tau (tTau) CSF immunoassays (Roche Diagnostics International Ltd) for measuring fresh CSF samples, and assess the concordance of the Elecsys CSF pTa

The genetic contributions to early onset heart failure (HF) are incompletely understood. Genetic testing in advanced HF patients undergoing heart transplantation (HTx) may yield clinical benefits, but data is limited. We performed deep-coverage whole genome sequencing (WGS) in 102 Swedish HTx recipients. Gene lists were compiled through a systematic literature review. Variants were prioritized for

In food engineering in general and in liquid food processing specifically, accurate measurement of particle size is important, both for product development and daily quality control. Laser diffraction is the dominating method for particle size measurement of e.g., plant cell structures in food and beverage processing. However, the accuracy of the method can be questioned since these particles diff

Effluent wastewater contains organic micropollutants (OMPs) that harm aquatic ecosystems. Therefore, wastewater treatment plants (WWTPs) need to expand their facilities with advanced water treatment technologies. Water scarcity and improved effluent quality is encouraging the reuse of treated effluent. This study thus has a dual purpose: first, to evaluate OMP removal using two technique combinati

Objective: To validate the ISGPS definition and grading system of PPAP after pancreatoduodenectomy (PD). Summary Background Data: In 2022, the International Study Group for Pancreatic Surgery (ISGPS) defined post-pancreatectomy acute pancreatitis (PPAP) and recommended a prospective validation of its diagnostic criteria and grading system. Methods: This was a prospective, international, multicente