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Aims: Recent studies have suggested potential sex differences in treatment response to pharmacological therapies in heart failure (HF). We performed a systematic review and meta-analysis of studies comparing treatment effects between men and women with HF and reduced ejection fraction (HFrEF) using established guideline-directed medical therapy and other emerging pharmacological treatments. Method
This research comment makes an argument on the need to develop epistemic communities of belonging. These are spaces facilitating conversations about and enabling transformative ethico-political research. A research practice that can invoke attentiveness, responsibility, curiosity, and awareness to the field we study. Rather than answering what we should do as intellectual activists to maintain eth
Objectives This study sought to study the second-generation everolimus-eluting stent (EES) as compared with first-generation sirolimus-eluting (SES) and paclitaxel-eluting stents (PES) in diabetes mellitus (DM) patients. Background There are limited data available comparing clinical outcomes in this setting with EES and SES, whereas studies comparing EES with PES are not powered for low-frequency
A series of four new analogue phases Ca2M2X (M = Pd, Pt and X = Al, Ge) were prepared by direct combination of the respective elements in stoichiometric mixtures at high temperature in order to analyze the impact of valence electron count (vec) and electronegativity differences (Delta chi) on the structure selection and stability. Their crystal structures, as determined from single-crystal X-ray d
Abstract: This paper provides one of the first studies on the role of social media in shaping collective memory in contemporary China. Social media enable the ordinary to participate in creating, interacting, and distributing alternative narratives of the past. Therefore, collective memory has being reconfigured under the influence of social media. Nevertheless, previous collective memory studies
Environmental concerns such as global warming, the surge of crude oil prices and more stringent emission regulations are demanding the development of internal combustion engines that are highly efficient and low polluting. With classical internal combustion engine concepts such as diesel compression ignition and gasoline spark ignition engines, a trade-off exists between local and global emissions
Background: The aim of this study was to examine in elderly men a relationship between depressive symptoms, peripheral vascular disease and cerebral blood flow (CBF). Methods: Population-based cohort study started with an examination of 809 men at age 55, followed by the first (age 68ys) and second follow up (age 82ys). 128 survivors were examined at age 82 with Tc-99m-HMPAO-SPECT to estimate CBF,
With the continued growth of digital services offering storage and communication of pictorial information, the need to efficiently represent this information has become increasingly important, both from an information theoretic and a perceptual point of view. There has been a recent interest to design systems for efficient representation and compression of image and video data that take the featu
Background The two main functional goals of postural control are postural stability (balance) and postural orientation. Postural orientation is the ability to maintain alignment between body segments and the environment during a static or dynamic activity. Nae et al. have evaluated the measurement properties of a clinical test battery for assessing postural orientation errors (POEs) in patients wi
Climate change will alter the hydrological cycle in the 21st century with implications for the water balance and water quality. As characteristics of the landscape may vary significantly between nearby locations, hydrological models need to be able to delineate responses attributed to specific landscape characteristics, to estimate their responses to altered climatic drivers. Small streams are the
Background: Although omic-based discovery approaches can provide powerful tools for biomarker identification, several reservations have been raised regarding the clinical applicability of gene expression studies, such as their prohibitive cost. However, the limited availability of antibodies is a key barrier to the development of a lower cost alternative, namely a discrete collection of immunohist
The aim of this thesis was to elucidate developments in epidemiology, clinical manifestations and complications in Chlamydia trachomatis (C.trachomatis) and Mycoplasma genitalium (M.genitalium) infection. In study I the frequencies of non-gonococcal salpingitis, gonococcal salpingitis and ectopic pregnancy (EP) were observed over a period of 28 years and correlated to the prevalence of Neisseria g
Context: Secondary hypogonadism is common in aging men; its natural history and predisposing factors are unclear. Objectives: The objectives were 1) to identify factors that predispose eugonadal men (T >= 10.5 nmol/L) to develop biochemical secondary hypogonadism (T < 10.5 nmol/L; LH <= 9.4 U/L) and secondary hypogonadal men to recover to eugonadism; and 2) to characterize clinical features associ
Background: Research involving expressed sequence tags ( ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and satisfactory annotated public sequence libraries are, however, available only for a limited range of organisms, rendering the absence of sequences and gene structure information a tangible problem for those working with ta
1. In a correlative study, we investigated the relative importance of fish predation, refuge availability and resource supply in determining the abundance and size distributions of the introduced and omnivorous signal crayfish (Pacifastacus leniusculus) in lakes and streams. Moreover, the biomass and food selection of predatory fish was estimated in each habitat type and stable isotopes of carbon
Under den gångna våren röstades ett nytt Copyrightdirektiv igenom i EU, vilket har rönt stor uppmärksamhet. Det rör sig om Europaparlamentets och rådets direktiv (EU) 2019/790 av den 17 april 2019 om upphovsrätt och närstående rättigheter på den digitala inre marknaden och om ändring av direktiven 96/9/EG och 2001/29/EG. Många hävdar att direktivet riskerar att leda till inskränkningar i yttrande-This Spring, a new Copyright Directive has been approved by the European Union, which has drawn a lot of attention. The Directive is formally known as Directive (EU) 2019/790 of the European Parliament and of the Council of 17 April 2019 on copyright and related rights in the Digital Single Market and amending Directives 96/9/EC and 2001/29/EC. Many people claim that this Directive may lead to lim
Uppsatsen innebär ett försök att utreda MER och AMA:s förhållande till AB 04 och hur de spelar in vid fastställande av entreprenadens omfattning. För att utreda frågeställningarna har en rättsdogmatisk metod använts. Den svenska entreprenadrätten har sedan lång tid setts som definierad av standardavtalen Allmänna bestämmelser. I Allmänna bestämmelser anges att entreprenadrättsligatvister ska lösaThe thesis involves an attempt to investigate MER and AMAS’s relationship with AB 04 and which role they play in determining the scope of the contract. The thesis determines the applicable law by using the legal dogmatic method. Swedish construction contract law has for a long period of time been defined by the use of a standard form contract called AB 04. Swedish construction contract law is a d
Det är viktigt att arbeta förebyggande för att förhindra att sexualbrott mot barn begås, inte minst eftersom sexualbrott kan få långtgående konsekvenser för den som blir utsatt. I Europarådets konvention om skydd för barn mot sexuell exploatering och sexuella övergrepp anges att varje part ska säkerställa eller främja effektiva förebyggande eller behandlande program eller åtgärder i syfte att förhPreventing sexual crimes against children is of great importance, not least due to the far-reaching consequences that sexual crimes can lead to for those who are exposed. The Council of Europe Convention on the Protection of Children against Sexual Exploitation and Sexual Abuse states that each party shall ensure or promote effective intervention programmes or measures with a view to preventing an
