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Introduction: Preoperative chemotherapy in early breast cancer increases the rate of breast preservation and provides prognostic information. Treatment decisions in these cases rely on biomarker assessments and subtyping from tissue acquired through core needle biopsies. Tumor heterogeneity and representativity are pit-falls when limited tissue is available. Biomarker expression may change conside

Occupational stress and the use of alcohol to reduce stress are both separately common in our society. A few researchers have combined the two factors. The aim of this essay was to obtain an increased understanding of how male and female managers estimate their alcohol habits in relation to their occupational stress. We have interviewed nine managers who work at a social services department in S

This study examines 24-months post-baseline outcomes for thirty-five Swedish antisocial youths who received either treatment in multidimensional treatment foster care (MTFC) or treatment as usual (TAU). MTFC is a community-based treatment programme that has been successful in treating chronic juvenile offenders in the USA. This study is the first randomized control study outside the USA. The youth

CONTEXT: Mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene cause rare syndromes characterized by altered bone mineral density (BMD). More common LRP5 variants may affect osteoporosis risk in the general population.OBJECTIVE: To generate large-scale evidence on whether 2 common variants of LRP5 (Val667Met, Ala1330Val) and 1 variant of LRP6 (Ile1062Val) are associated w

It is well-known that the response to mechanical loading of nano-sized metal structures differs from what applies to the macroscopic scale, and often non-intuitive behaviors are revealed. Here beams of square cross section, containing defects in terms of voids and loaded in fatigue with R = 0 under displacement controlled conditions, are investigated. The structures under consideration are single-

The foundational economy perspective suggests that industries, which provide services essential to all citizens’ well-being and participation in everyday life, should be placed centrally in economic development policy. This article studies the extent to which local governments put emphasis on foundational industries in their strategies for development. Moreover, drivers behind priority-setting are

Objective To determine the yield of tuberculosis (TB) and the prevalence of Human Immuno-deficiency virus (HIV) among key populations in the selected hotspot towns of Ethiopia. Methods We undertook a cross-sectional implementation research during August 2017-January 2018. Trained TB focal persons and health extension workers (HEWs) identified female sex workers (FSWs), health care workers (HCWs),

Bakgrund: Fallolyckor har ökat den senaste tiden och orsakar stora kostnader för samhället samt lidande för den drabbade. Det är viktigt att sätta in insatser i fallprevention för att motverka detta. Socialstyrelsen har samordnat en kampanj på uppdrag från regeringskansliet för dessa insatser. I dagsläget används instrument med mått som är ospecifika samt svåra att kvantifiera för att utvärdera fa

Titel: Du sköna nya konsument - En kvalitativ studie om hur konsumenter resonerar kring virtuella recensioner. Datum för seminarium: 2016-06-02 Kurs: FEKH29, Kandidatuppsats i marknadsföring, 15HP Författare: Filip Dahlin, Marit Joten och Nils Nordström. Handledare: Clara Gustafsson Syfte: Syftet är att skapa en förståelse för hur konsumenter resonerar kring virtuella recensioner. Uppsatsen s

The awareness of problems concerning arsenic contaminated drinking water sources has during recent years increased. WHO (World Health Organization) decided in 1993 to lower the recommended limit of arsenic in drinking water from 50 μg/l to 10 μg/l, mainly due to observations of its carcinogenicity. New places where the WHO limit for arsenic is exceeded are constantly discovered all over the world.

The awareness of problems concerning arsenic contaminated drinking water sources has during recent years increased. WHO (World Health Organization) decided in 1993 to lower the recommended limit of arsenic in drinking water from 50 μg/l to 10 μg/l, mainly due to observations of its carcinogenicity. New places where the WHO limit for arsenic is exceeded are constantly discovered all over the world.

Bakgrund: Höga ljudnivåer och bullerskador är ett vanligt problem på arbetsplatser. Många väljer att inte använda hörselskydd då de upplevs försvåra kommunikation. En metod som med ett enkelt mått kan utvärdera hörselskydds påverkan av taluppfattning vore värdefullt. Syfte: Syftet med studien var att undersöka möjligheten att med metoden Speech intelligibility impact Level (SiimpL) mäta skillnad m

This thesis evaluates if a countrywide female-related healthcare intervention in 2015 affected Swedish regions’ maternal health outcomes differently due to a decentralized healthcare system. By exploiting regions’ varying budget dedicated to female-related healthcare before the intervention, the size of the budget increase is estimated. Maternal health outcomes before and after the intervention ar

Importance: Chronic kidney disease (CKD) has been associated with increased plasma concentrations of phosphorylated tau (p-tau) 217 and p-tau181, which potentially decreases their usefulness in the diagnostic workup of Alzheimer disease (AD). Objective: To investigate associations of CKD with plasma ratios of p-tau217 and p-tau181 to the corresponding unphosphorylated peptides in AD. Design, Setti