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Opus 106b. Composition: Alexander von Zemlinsky. Lyrics by Ferdinand Gregorovius, Constance Bache. A version of this work already exists for soprano and chamber orchestra, but I have adapted it for soprano and string quartet.

Background: Fentanyl is commonly administered for procedural pain management in preterm infants, but target concentrations have not yet been defined. Methods: To investigate pharmacokinetics (PK), -dynamics (PD), and -genetics (PG), 25 infants (gestational age 23.3–34.1 weeks) received a fentanyl dose before a skin-breaking procedure (0.5 µg/kg) or tracheal intubation (2 µg/kg). Four pain scales w

The National Institute on Aging and the Alzheimer's Association convened three separate work groups in 2011 and single work groups in 2012 and 2018 to create recommendations for the diagnosis and characterization of Alzheimer's disease (AD). The present document updates the 2018 research framework in response to several recent developments. Defining diseases biologically, rather than based on synd

The age-standardized prevalence of Parkinson's disease (PD) has increased substantially over the years and is expected to increase further. This emphasizes the need to identify modifiable risk factors of PD, which could form a logical entry point for the prevention of PD. The World Health Organization (WHO) has recommended reducing exposure to specific environmental factors that have been reported

Navigation performance in urban and large-scale built-up spaces (e.g. airports, train-stations, hospitals) depends on gradual environmental perception during locomotion, and spatial knowledge acquisition, update/integration at different times along a path. Rotational locomotion is regularly involved in everyday navigation; this, combined with the fact that people cannot perceive the whole of a lar

The open source CFD code FireFOAM has been verified and validated against analytical solution and real fire tests. The verification showed that FireFOAM solves the three modes of heat transfer appropriately. The validation against real fire tests yielded reasonable results. FireFOAM has not been validated for a large set of real fires, which is the case for FDS. Therefore, it is the responsibility

Phase-noise (PN) estimation and compensation are crucial in millimeter-wave (mmWave) communication systems to achieve high reliability. The PN estimation, however, suffers from high computational complexity due to its fundamental characteristics, such as spectral spreading and fast-varying fluctuations. In this paper, we propose a new framework for low-complexity PN compensation in orthogonal freq

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the effects of pharmacological interventions for pain and sedation management in newborn infants undergoing therapeutic hypothermia.

This paper shows the advantage of using both 3d models and surgical navigation system when preparing and planning complex brain surgery. The novel clinical process introduced here combine CT and MRI images in special computer program where the regions of interest are isolated e.g. the skull base, tumor and other soft tissue. A 3D model is calculated from the segmented m

This paper presents a bottom boundary layer model for the unsteady and non-uniform flow in the swash zone, by extending the momentum integral method so as to include spatial gradients. The developed model is further incorporated into a hydrodynamic model based on the Nonlinear Shallow Water Equations. Two swash zone cases are examined to investigate the effect of the inclusion of spatial gradients

There is currently interest in low strain HPHT diamond due to its expected application as various types of X-ray optical elements at Synchrotrons, where the X-ray intensity is becoming progressively too severe for the existing materials. The diamond crystals need to be synthesised with unprecedented lattice quality. In recent measurements at the ID19 beamline of European Synchrotron Radiation Faci

Paraffin wax and various nanoparticles (CuO, Al2O3 and Fe3O4) were used as matrix and heat conduction enhancer of phase change materials (PCMs), respectively. The dispersant Span 80 was added into the nanocomposite to provide stable PCMs. Based on analyses of melting and freezing curves and infrared thermal imaging tests, the phase change latent heat, viscosity, and thermal conductivity of the nan

Creating a more sustainable society is increasingly an urban challenge (Pincetl 2010). Upwards of 50 per cent of the world’s population currently dwell in cities, and this figure is forecast to rise dramatically over the coming decades (Grimm et al. 2008). Cities both concentrate the activities that produce carbon emissions, and suffer disproportionately from their negative impacts such as air pol

The stability of dispersions containing charged particles may obviously be regulated by salt. In some systems, the effective charge, as measured by the potential some small distance away from the particles, can have a sign opposite to the bare surface charge. If charge reversal takes place, there is typically a salt concentration regime within which colloidal stability increases with added salt. T

Vapor phase infiltration into a self-assembled block copolymer (BCP) to create a hybrid material in one of the constituent blocks can enhance the etch selectivity for pattern transfer. Mul- tiple pulse infiltration into carbohydrate-based high-χ BCP has previously been shown to enable sub-10 nm feature pattern transfer. By optimizing the amount of infiltrated material, the etch selectiv- ity shoul

While the virus SARS-CoV-2 spreads all over the world, most countries have taken severe measures to protect their citizens and slow down the further spread of the disease COVID-19. These measures affect individuals, communities, cities, countries, and the entire planet. In this paper, we propose that the tremendous consequences of the corona crisis invite environmental psychology to focus more str

All patients in a randomized study comparing chemotherapy with chemotherapy plus radiotherapy for patients with astrocytomas grade 3 and 4, were considered for reoperation when tumour progression was established. Fifty-eight patients were reoperated and 85 were not. Different prognostic factors, such as age, sex, Karnofsky performance status and reoperation were evaluated univariately and simultan

Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively

Background: Preterm infants are susceptible to hyperglycaemia and hypoglycaemia, which may lead to adverse neurodevelopment. The use of continuous glucose monitoring (CGM) devices might help in keeping glucose levels in the normal range, and reduce the need for blood sampling. However, the use of CGM might be associated with harms in the preterm infant. Objectives: To assess the benefits and harms