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Cancer cells display acoustic properties enabling acoustophoretic separation from white blood cells (WBCs) with 2–3 log suppression of the WBC background. However, a subset of WBCs has overlapping acoustic properties with cancer cells, which is why label-free acoustophoretic cancer cell isolation needs additional purification prior to analysis. This paper reports for the first time a proof of conc

During development, hematopoietic cells originate from endothelium in a process known as endothelial-to-hematopoietic transition (EHT). To study human EHT, we coupled flow cytometry and single-cell transcriptional analyses of human pluripotent stem cell-derived CD34(+) cells. The resulting transcriptional hierarchy showed a continuum of endothelial and hematopoietic signatures. At the interface of

In this paper we examine health among breast cancer 5-year survivors. We raise two questions: (1) how do the health level of this survival group compare to the health level of the general population; and (2) how have the health levels among these survivors changed over time. We found that 5-year breast cancer survivors assess their health lower than the general population, and that having being di

The aim of this study was to investigate why some people will and can work until they are 65 year or more, and some people not either can or will. The study was built at answers from 2 000 employees within the health and medical care services. The data material was divided into three groups from the answers. Group 1 who cannot and will not work until 65 years. Group 2 who can and will work until 6

Empirical findings indicate a need of support for environmental management within the manufacturing industry for improving the environmental performance of their production systems. This paper elaborates on a generic, three step visualization tool, here called Green Performance Map (GPM). The GPM adds to the framework of ISO 14001, providing the user with a systematic procedure to visualize enviro

ABSTRACT: BACKGROUND: Evaluation of an implementation process and its fidelity can give insight into the 'black box' of interventions. However, a lack of standardized methods for studying fidelity and implementation process have been reported, which might be one reason for the fact that few prior studies in the field of health service research have systematically evaluated interventions' implement

BACKGROUND: The association of early knee joint laxity with the need for later reconstruction of the anterior cruciate ligament has not been extensively studied. HYPOTHESIS: The grade of knee laxity can be used as an early predictor of the need for later reconstruction. STUDY DESIGN: Cohort study (prognosis); Level of evidence, 2. METHODS: One hundred consecutive patients with an acute arthroscopi

Addiction treatment often requires medical, psychosocial and social expertise - and benefits from collaboration. The pronounced role of social authorities in evaluation and treatment is unique to the addiction field. Unified responsibility for evaluation and treatment of addiction is under consideration. Treatment of psychiatric and physical co-morbidity benefits from a unified responsibility with

I denna artikel undersöks hur hemtjänsten påverkar äldre personer i Sverige, med fokus på hur den på ett subtilt sätt kan institutionalisera deras dagliga liv. Hemtjänsten visar sig ha en inverkan på brukarnas individualitet och självständighet, i motsats till de ursprungliga intentionerna att erbjuda ett frigörande alternativ till vårdinrättningar.I studien används Goffmans begrepp ”totala instit

AimPeak oxygen uptake (VO2peak) is closely related to total heart volume (THV) in healthy individuals. This study aimed to investigate 1) the association between VO2peak and THV in subjects with subclinical diastolic dysfunction, athletes, healthy controls, and patients with established heart failure with and without preserved ejection fraction (HFpEF, HFrEF), and 2) whether VO2peak/THV-index can