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The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality. Here we report a multi-ancestry (N = 293,051) genome-wide association meta-analysis for the PR interval, discovering 202 loci of which 141 have not previously been reported. Variants at identified

The authors investigated whether PCSK9 inhibition could represent a therapeutic strategy in calcific aortic valve stenosis (CAVS). A meta-analysis of 10 studies was performed to determine the impact of the PCSK9 R46L variant on CAVS, and the authors found that CAVS was less prevalent in carriers of this variant (odds ratio: 0.80 [95% confidence interval: 0.70 to 0.91]; p = 0.0011) compared with no

The authors have developed a porous silicon (P-Si) based duplex antibody microarray platform for simultaneous quantitation of the biomarkers prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in serum. Pore size-controlled P-Si surfaces have an extremely enlarged surface area that enables high-density immobilization of fluorescently labeled antibodies by physical adsorption. Au

Purpose: The purpose of this study was to explore the relationship between oxidative stress, antioxidant defense, mitochondrial structure, and biomechanical tissue support in the isolated porcine retina.Methods: Full-thickness retinal sheets were isolated from adult porcine eyes. Retinas were cultured for 2 or 48 h using (1) a previously established low-support explant protocol with photoreceptors

FRS & RS v 49.xlsx Beslut på rektorssammanträdet 5 december Närvarande vid sammanträdet utöver föredragande: Rektor Torbjörn von Schantz Förvaltningschef Susanne Kristensson Ordförande LUS Gustav Ekström Vice ordförande LUS Matilda Byström Utredare Carina Wickberg (sekreterare) 1 Anställning som gästprofessor i tillämpad matematik (PA 2019/3329) – Helen Johansson 2 Förnyad anställning som gästprof

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/00-beslutslista-rs-191205.pdf - 2026-06-01

Utbildningsplan_Musikdramatik_REPETITÖR_2019_IS_3 april_BeLi_GÄLLANDE Utbildningsplan Musikerutbildning – Musikdramatik – repetitör, 120 hp - master 1. IDENTIFIKATION • Programmets namn och inriktning: musikerutbildning, musikdramatik - repetitör. • Omfattning i högskolepoäng: 120. • Nivå: Avancerad nivå (A). • Programkod: KAMUS. Inriktning: MURE 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad

https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildningsplan_musikdramatik_repetitor_2019_is_3_april_beli_gallande.pdf - 2026-06-01

Family burden of cardiovascular mortality: risk implications for offspring in a national register linkage study based upon the Malmö Preventive Project Family burden of cardiovascular mortality: risk implications for offspring in a national register linkage study based upon the Malmö Preventive Project P . M . N I L S S O N , J . - Å . N I L S S O N & G . B E R G L U N D Department of Medicine,

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/jim_family_history_cvd_2004.pdf - 2026-06-01

Genusvetarnas framtid Anna Lundberg & Ann Werner en skriftserie om Genusvetenskap Genusvetarnas framtid en nationell alumniundersökning av genusvetenskaplig utbildning och arbete anna Lundberg och ann Werner 5Genusvetarnas framtid Genusvetarnas framtid – En nationell alumniundersökning av genusvetenskaplig utbildning och arbete Nationella sekretariatet för genusforskning Box 709 405 30 Göteborg ©N

https://www.genus.lu.se/sites/genus.lu.se/files/genusvetarnas_framtid_2013.pdf - 2026-06-01

A new approach for ratiometric in vivo calcium imaging of microglia 1Scientific REPORTS | 7: 6030 | DOI:10.1038/s41598-017-05952-3 www.nature.com/scientificreports A new approach for ratiometric in vivo calcium imaging of microglia Bianca Brawek1, Yajie Liang1, Daria Savitska1, Kaizhen Li1, Natalie Fomin-Thunemann1, Yury Kovalchuk1, Elizabeta Zirdum1, Johan Jakobsson 2 & Olga Garaschuk1 Microglia,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_sci_rep.pdf - 2026-06-01

Lokalt kollektivavtal 2023-08-21 1 ( 4) STYR 2023/1543 LUNDS UNIVERSITET Sektionen HR Lokalt kollektivavtal om ersättning vid beredskap Parter: Lunds universitet OFR/S Saco-S Seko 1 § Parterna sluter lokalt kollektivavtal om ersättning vid beredskap. Avtalet sluts med stöd av 2 kap. 2§ Villkorsavtal (OFR/S respektive Seko) och Villkortsavtal-T (Saco-S). Avtalet ska ha den lydelse som framgår av bi

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-01/Lokalt%20kollektivavtal%20om%20ers%C3%A4ttning%20vid%20beredskap%20(STYR%202023-1543).pdf - 2026-06-01

Cell-type-specific neuronal activation the sensorimotor cortex in L-DOPA-induced dyskinesia Markus Aldén1, Osama Elabi1, Martina Harley Leanza1, M. Angela Cenci1 1. Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden L-DOPA-induced dyskinesia (LID) is a common complication of Parkinson´s disease pharmacotherapy. Knowledge about the involvem

https://www.neuroscience.lu.se/sites/neuroscience.lu.se/files/2026-05/all_abstracts.pdf - 2026-06-01

BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy

Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular traits (36,203 UK Biobank participants). We identified 80 genomic risk loci and prioritized 62 putative effector genes, including several with rare variant DCM associations (MAP3K7, NEDD4L a

The compositions of alternative jet fuels can vary radically, and the consequences of these differences are a subject of ongoing investigation. Numerical combustion simulations are vital to this research and require chemical reaction mechanisms that efficiently and accurately capture the chemical pathways of combustion. Here, we present the recently developed Z79 collection of small pathway-centri

Ribbed channel flows play a crucial role in various engineering systems where turbulence enhancement and improved heat transfer are required, such as in turbine blade cooling and combustor wall applications. Numerical simulations have emerged as an essential tool for analyzing the intricate turbulence dynamics and flow separation phenomena, which are fundamental for optimizing the channel performa

Lean, premixed, swirl-stabilized flames are widely used in modern Dry Low Emissions gas turbine combustors; however, the turbulent combustion process under those conditions is known to be extremely sensitive and prone to instabilities. Numerical simulations can be a valuable tool in predicting the effects of alternative fuels; however, the sensitivity of the results to different models ought to be

Background: The incorporation of artificial intelligence (AI) into point-of-care ultrasound (POCUS) platforms has rapidly increased. The number of B-lines present on lung ultrasound (LUS) serve as a useful tool for the assessment of pulmonary congestion. Interpretation, however, requires experience and therefore AI automation has been pursued. This study aimed to test the agreement between the AI

BACKGROUND: Atrial fibrillation (AF) is suggested to be associated with venous thromboembolism (VTE) and might thereby play a role in the development of chronic thromboembolic pulmonary hypertension (PH). By elevating left-sided filling pressure and promoting atrial myopathy, AF may also play a role in the development of postcapillary PH. We aimed to investigate the association between AF, with or

PEDI3945064 1..11 Research Article Dietary Intake and Body Mass Index Influence the Risk of Islet Autoimmunity in Genetically At-Risk Children: A Mediation Analysis Using the TEDDY Cohort Carin Andrén Aronsson ,1 Roy Tamura,2 Kendra Vehik,2 Ulla Uusitalo,2 Jimin Yang,2 Michael J. Haller,3 Jorma Toppari,4,5 William Hagopian,6 Richard A. McIndoe,7 MarianJ.Rewers,8Anette-G.Ziegler,9BeenaAkolkar,10 J

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-11/156%20_MP148_Aronsson_PedDiab_2023_0.pdf - 2026-06-01

Obesity’s metabolic heterogeneity is not fully captured by body mass index (BMI). Here we show that deep multi-omics phenotyping of 1,408 individuals defines a metabolome-informed obesity metric (metBMI) that captures adipose tissue-related dysfunction across organ systems. In an external cohort (n = 466), metBMI explained 52% of BMI variance and more accurately reflected adiposity than other omic