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Concentration of viable cell populations in suspension is of interest for several clinical and pre-clinical applications. Here, we report that microfluidic acoustophoresis is an effective method to efficiently concentrate live and viable cells with high target purity without any need for protein fluorescent labeling using antibodies or over-expression. We explored the effect of the acoustic field
Background: Untargeted metabolomic analysis provides novel insights into the relationship between sodium intake and cardiometabolic risk. This study examined cross-sectional associations between estimated sodium intake and plasma metabolite profiles in a large Swedish cohort. Methods: This cross-sectional analysis was conducted in the in the SCAPIS cohort (mean age 50–64 years, n = 8,957). Sodium
Background: There is mounting evidence supporting the role of the microbiota in hypertension from experimental studies and population-based studies. We aimed to investigate the relationship between specific characteristics of the gut microbiome and 24-h ambulatory blood pressure measurements. Methods: The association of gut microbial species and microbial functions, determined by shotgun metagenom
With the foreign political turbulence after the fall of the Berlin Wall, the world came into a change. The post-cold war environment meant that the politics of the bipolarity no longer were the case. This period leads to pressure in redefining Sweden’s foreign and security policy, resulting in an emergence of a different commitment to the countries neutrality and non-alignment. In the light of Kje
The failure of many countries in the Global South to catch up economically to the advanced economies of the Global North has long been a topic of interest to economic historians and development economists. Traditionally, researchers focused their attention on the question of growth –how can a country achieve growth to catch up? In recent years, however, a new research programme has begun to shift
Objective: Meat intake is suggested to affect gut microbiome composition and the risk of chronic diseases. We aimed to identify meat-associated gut microbiome features and their association with host factors. Design: Gut microbiota species were profiled by deep shotgun metagenomics sequencing in 9669 individuals. Intake of white meat, unprocessed red meat, and processed red meat was assessed using
CONTEXT: Type 2 diabetes is a growing global concern with serious complications, including kidney damage and cardiovascular morbidity and mortality. Monitoring albuminuria, which is associated with these complications, is crucial in optimal diabetes management. Gut microbiota composition has been suggested to impact albuminuria, but large studies with granular data are lacking.METHODS: We investig
Background: Higher meat intake has been associated with adverse health outcomes, including cardiovascular disease (CVD). This study investigated plasma metabolites associated with meat intake and their relation with cardiometabolic biomarkers, subclinical CVD markers, and incident CVD. Methods: Associations between self-reported meat intake and 1272 plasma metabolites were investigated in the SCAP
In 1736 Samuel Hesselius, former pastor for the Swedish parishes in Pennsylvania, donated a collection of ‘American curiosities’ to Lund University in Sweden. Within less than twenty years, however, the collection had apparently disappeared. In the course of the past three decades the lost ethnographic artefacts have received increasing attention, but for a variety of reasons the collection has reIn 1736 Samuel Hesselius, former pastor for the Swedish parishes in Pennsylvania, donated a collection of ‘American curiosities’ to Lund University in Sweden. Within less than twenty years, however, the collection had apparently disappeared. In the course of the past three decades the lost ethnographic artefacts have received increasing attention, but for a variety of reasons the collection has re
This paper explores the evolution of Swedish stabilization policies through six policy regimes between 1873 and 2019. We focus on discretionary policy decisions by estimating policy shocks using a SVAR model. Through these shocks, we explore how stabilization policies have evolved over time and how policymakers responded to key economic events such as financial crises and wars. Our results show thThis paper explores the evolution of Swedish stabilisation policies through six policy regimes between 1873 and 2019. We focus on discretionary policy decisions by estimating policy shocks using a SVAR model. Through these shocks, we explore how stabilisation policies have evolved over time and how policymakers responded to key economic events such as financial crises and wars. Our results show th
The fields of human genetics and genomics have generated considerable knowledge about the mechanistic basis of many diseases. Genomic approaches to diagnosis, prognostication, prevention and treatment – genomic-driven precision medicine (GDPM) – may help optimize medical practice. Here, we provide a comprehensive review of GDPM of complex diseases across major medical specialties. We focus on tech
Background: Post heart-transplant survival has increased, but information is lacking on specific causes of death and life expectancy. We aimed to assess cause-specific loss of life-years compared to the general population, evaluate classification for cause of death after heart transplantation, and assess validity of cause of death data from the International Society of Heart and Lung Transplant (I
Aims: Bioactive adrenomedullin (bio-ADM) is a vascular-derived peptide hormone that has emerged as a promising biomarker for assessment of congestion in decompensated heart failure (HF). We aimed to evaluate diagnostic and prognostic performance of bio-ADM for HF in comparison to amino-terminal pro-B-type natriuretic peptide (NT-proBNP), with decision thresholds derived from invasive haemodynamic
The enzymatic modification of natural oat oils enriched with polar lipids (PL), consisting mainly of equal mixture of phospholipids and galactolipids, offers a sustainable pathway to produce liquid crystalline phases (LCPs) with diverse structural arrangements, including micellar or bicontinuous cubic and hexagonal phases. These self-assembling lipid systems have potential applications in drug del
AIMS: Patients awaiting orthotopic heart transplantation (OHT) can be bridged utilizing a left ventricular assist device (LVAD) that reduces left ventricular filling pressures, decreases pulmonary artery wedge pressure, and maintains adequate cardiac output. This study set out to examine the poorly investigated area of if and how pre-treatment with LVAD impacts right ventricular (RV) function foll
Background: OSA is a common sleep-breathing disorder linked to increased risk of cardiovascular disease. Intermittent upper airway obstruction and hypoxia, hallmarks of OSA, have been shown in animal models to induce substantial changes to the gut microbiota composition, and subsequent transplantation of fecal matter to other animals induced changes in BP and glucose metabolism. Research Question:
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors ARTICLE Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors Marie E Jönsson1, Per Ludvik Brattås1, Charlotte Gustafsson2, Rebecca Petri1, David Yudovich3, Karolina Pircs1, Shana Verschuere1, Sofia Madsen1, Jenny Hansson 4, Jonas Larsson3,
Cell-based therapies for Parkinson disease—past insights and future potential NATURE REVIEWS | NEUROLOGY ADVANCE ONLINE PUBLICATION | 1 John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Cambridge CB2 0PY, UK (R.A.B.). Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund U
Minutes2014-10-27 SASNET Swedish South Asian Studies Network Styrelsemöte, 27 oktober 2014, 13.30-16.00 Plats: Konferensrum 3, våning 2, Avdelningen för Sociologi, Lunds Universitet, Paradisgatan 5 Närvarande styrelsemedlemmar: Anna Lindberg, Fredrik Tufvesson, Anders Fänge, Olle Qvarnström (från 14.10), Adjungerade ledamöter: Olle Frödin och Lars Eklund Studentrepresentanter: Lubna Hawwa,
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/board1403.pdf - 2026-05-31
