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Long-term Results of Cardiac Resynchronization Therapy; A Comparison Between CRT-Pacemakers Versus Primary Prophylactic CRT-Defibrillators.

Cardiac resynchronization Therapy (CRT) with or without a defibrillator has a positive effect on mortality and morbidity for patients with heart failure. However, comparisons between CRT-Defibrillators (CRT-D) and CRT-Pacemakers (CRT-P) are relatively scarce outside the clinical trial setting. This study aimed to assess baseline characteristics in relation to long-term prognosis in patients treate

Consumer Welfare and EU Merger Control - How Does it Tip the Scales?

Att upprätthålla välfärden för konsumenter inom EU är en av grundprinciperna för EU:s konkurrensrättsliga regelverk och praxis, något som leder till att alla konkurrensrättsliga bedömningar som genomförs av Kommissionen bör genomsyras av ett tänk som ser till det bästa för upprätthållandet av just denna välfärd. Denna inställning till skydd för konsumenter är särskilt framträdande inom EU:s regelvThe consumer welfare standard is one of the fundamental principles of EU competition law and practice. This means that all competitive assessments conducted by the Commission should have the welfare of consumers in mind to make sure that it is not harmed. This approach to protecting consumer welfare is especially prominent within the EU framework for corporate concentrations, where it is an intrin

Does the Gender-Equality-Personality-Paradox Depend on the Scoring Method? The Implications of Measurement Invariance

With increasing country-level gender equality, country-level gender differences in personality are found to increase. This is known as the Gender-Equality-Personality-Paradox (GEPP). Possibly, the GEPP is a methodological artefact. So far, the personality trait scoring method has not been investigated as a potential source of the GEPP. Three kinds of scores were investigated in the present study:

Do some cases of anorexia nervosa reflect underlying autistic-like conditions?

In a sample of 51 teenagers with anorexia nervosa (AN)-which included 24 cases constituting the total population of AN cases born in 1970-several had shown social, communicative and behaviour patterns suggestive of autistic-like conditions as children, long before the onset of AN. One of the three boys in the AN group had Asperger syndrome. Three of the 48 girls had histories suggesting high funct

Galactomannan catabolism conferred by a polysaccharide utilisation locus of Bacteroides ovatus : enzyme synergy and crystal structure of a β-mannanase

A recently identified polysaccharide utilization locus (PUL) from Bacteroides ovatus ATCC 8483 is transcriptionally up-regulated during growth on galacto- and glucomannans. It encodes two glycoside hydrolase family 26 (GH26) β-mannanases, BoMan26A and BoMan26B, and a GH36 α-galactosidase, BoGal36A. The PUL also includes two glycan-binding proteins, confirmed by β-mannan affinity electrophoresis. W

Register-based studies to assess long-term outcome in haemophilia

IntroductionHaemophilia is a X-linked bleeding disorder affecting mostly males. Women are mainly carriers ofhaemophilia, however, they can expereince high bleeding tendency and assocaited symptoms aswith males. In the absence of the appropriate treatment, bleedings, especially into the joints, result inadverse outcomes. The general aim of this thesis was to promote the use of register-based data t

Prediction of recidivism in a long-term follow-up of forensic psychiatric patients : Incremental effects of neuroimaging data

One of the primary objectives in forensic psychiatry, distinguishing it from other psychiatric disciplines, is risk management. Assessments of the risk of criminal recidivism are performed on a routine basis, as a baseline for risk management for populations involved in the criminal justice system. However, the risk assessment tools available to clinical practice are limited in their ability to pr

The metabolic cost of subcutaneous and abdominal rewarming in king penguins after long-term immersion in cold water

Marine endotherms in the polar regions face a formidable thermal challenge when swimming in cold water. Hence, they use morphological (fat, blubber) adjustment and peripheral vasoconstriction to reduce demands for heat production in water. The animals then regain normothermia when resting ashore. In the king penguin (Aptenodytes patagonicus) metabolic rate is lower in fed than in fasted individual

Investigation of GARCH Models for the Estimation Power and Normality

The aims of the thesis are to investigate the estimation power and the normality of standardized residuals for Generalized autoregressive conditional heteroscedasticity models (GARCH). We facilitate the analysis by only dealing with GARCH(1, 1) models. We take use of MATLAB as the statistical programming tool for the simulation of the data and the estimation. We define the meaning of estimation

SELective defunctioning Stoma Approach in low anterior resection for rectal cancer (SELSA) : Protocol for a prospective study with a nested randomized clinical trial investigating stoma-free survival without major LARS following total mesorectal excision

Aim: Accumulated data suggest that routine use of defunctioning stoma in low anterior resection for rectal cancer may cause kidney injury, bowel dysfunction and a higher risk of permanent stomas. We aim to study whether avoidance of a diverting stoma in selected patients is safe and reduces adverse consequences. Methods: SELSA is a multicentre international prospective observational study nesting

A feasibility and safety trial investigating a device for swift and standardized median laparotomy closure

Purpose: Abdominal wall complications can be reduced by adhering to guidelines for midline laparotomy closure. However, implementation of guidelines can be challenging. To address this issue, a laparotomy closure device for swift and standardized abdominal closure was developed. The study evaluated the quality of the suture, safety, and speed of the device in a clinical setting. Methods: A prospec

Investigations on fouling and cleaning of membranes used for direct membrane filtration of municipal wastewater

The concept of direct membrane filtration (DMF) is relatively new for treating municipal wastewater. In contrast to a conventional membrane bioreactor, DMF decouples filtration and biological treatment. This presentation is based on a pilot scale DMF study conducted at the municipal wastewater treatment plant in Svedala (Sweden), combined with lab-scale experiments and analysis to optimise the pil

An investigation of moisture and leakage currents in GRP composite hollow cylinders

The applicability of using flat composite plates and hollow core composite cylinders for moisture absorption testing of unidirectional glass/polymer composites used in high voltage composite (non-ceramic) insulators was examined. Two main issues were addressed in this work. First, the effect of specimen geometry (cylinders vs. plates) on moisture absorption by the composites was investigated both

Miocene climate evolution of northern Europe: A palynological investigation from Denmark

A palynological investigation has been conducted on Lower-Upper Miocene sediments from Jylland, Denmark, corresponding to the time interval of about 19 to 8 Ma. The sediments, derived from the Sdr. Vium drill core, were deposited in marine to marginal-marine environments, as shown by the relatively high abundance of dinoflagellate cysts in all samples. Nevertheless, rich and diverse pollen assembl

Do common frogs (Rana temporaria) follow Bergmann's rule?

Questions: Does intraspecific extension of Bergmann's rule - larger size within a species in cooler areas - hold true for ectotherms in general, and for the common frog (Rana temporaria) in particular? What is the relative importance of genetic and environmental factors (i.e. direct environmental induction) in determining latitudinal patterns of body size variation in common frogs? Methods: We tes

A comprehensive, time-resolved SANS investigation of temperature-change-induced sponge-to-lamellar and lamellar-to-sponge phase transformations in comparison with 2H -NMR results

Time-resolved small-angle neutron scattering (TR-SANS) was employed to observe temperature-induced phase transitions from the sponge (L-3 to the lamellar ( L (alpha) phase, and vice versa, in the water-oil (n-decane)-non-ionic surfactant (C12E5 system using both bulk and film contrast. Samples of different bilayer volume fractions phi and solvent viscosities eta were investigated applying various

Diabetes mellitus, glycated haemoglobin and C-peptide levels in relation to pancreatic cancer risk: a study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Aims/hypothesis There has been long-standing debate about whether diabetes is a causal risk factor for pancreatic cancer or a consequence of tumour development. Prospective epidemiological studies have shown variable relationships between pancreatic cancer risk and blood markers of glucose and insulin metabolism, overall and as a function of lag times between marker measurements (blood donation) a

Healthcare costs for people aged 65+ two years prior to their receiving long-term municipal care.

BACKGROUND AND AIMS: More knowledge is needed about patterns of healthcare consumption at different times during old age, particularly with regard to the relationship between various agents in the healthcare and social services system. One aim was to investigate healthcare costs in the public medical healthcare system in men and women (65+) and, with regard to age, in the two years prior to the st

Does the Current Constraints in Funding Promote Failure in Humanitarian Supply Chains?

Traditionally, most funding is made available when a disaster occurs. Disaster re-sponse is the implementation of what humanitarian actors did (or didn't do) in pre-paredness for any intervention. Based on a case study of a logistics change in the International Federation of Red Cross Red Crescent Society, this paper discusses how more funding of preparedness can radically improve the speed and qu