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This study describes an atrial fibrillation (AF) detector whose structure is well-adapted both for detection of subclinical AF episodes and for implementation in a battery-powered device for use in continuous long-term monitoring applications. A key aspect for achieving these two properties is the use of an 8-beat sliding window, which thus is much shorter than the 128-beat window used in most exi

Objectives. During the past decade, the position of biologics in the therapeutic armamentarium, the number of approved indications and the number of available biologics have changed. Available data on (long-term) safety might thus pertain to patient populations not comparable with contemporary patients. The aim of this study was to assess the extent to which contemporary patients who start or swit

Blandine Lyonnard How microbes in different soils react to drought and rainfall? Drought periods followed by rainfall events induce large release of CO2 from the soil to the atmosphere. This phenomenon, known as the “Birch effect” can contribute to global warming. With climate change, there will be more and more cycles of drought followed by rainfall events. Therefore, there will be more Birch e

Slow and hovering animal flight creates high demands on the lift production of animal wings. Steady state aerodynamics is unable to explain the forces required and the most commonly used mechanism to enhance the lift production is a leading edge vortex (LEV). Although LEVs increase the lift, they come at the cost of high drag. Here we determine the flow above the wing of lesser long-nosed bats at

Vid revideringen av brottsbalken 1989 infördes det billighetsskäl i 29 kap. 5 § BrB som rätten utöver brottets straffvärde ska beakta vid straffmätningen. Omständigheterna som räknas upp i paragrafen är sådana som inträffat efter brottets genomförande eller som har med den tilltalades personliga omständigheter att göra. Rätten får, med stöd av billighetsskälen, döma till lindrigare straff än vad sDuring the penal code reform 1989, clemency pleas were introduced in the Swedish legal system. Chapter 29 § 5 in the penal code states that the court, except the penal value, should take into account the circumstances after the crime has been committed as well as the defendant’s personal conditions when evaluating possible punishments. The court must take these clemency pleas into account in order

Corporate Social Responsibility (CSR) is a term increasingly used in academic discussions, political debates, media, corporate reports, Non-Governmental Organizations’ (NGOs) reports, and even by civil society and the public. But what does CSR actually mean? What do CSR practices actually constitute? Another increasingly debated issue is the growing power of the business sector and its direct effe

Daily rain series from southern Sweden with records dating back to the 1870s have been analysed to investigate the trends of daily and multi-day precipitation of different return periods with emphasis on the extremes. Probabilities of extreme storms were determined as continuously changing values based on 25 years of data. An extra set of data was used to investigate changes in Skane, the southern

Background: Will being a caregiver further impact the health of a group already at risk of adverse health due to old age? This study aimed to answer the questions whether short- and long-term healthcare consumption and mortality differ between informal caregivers and non-caregivers and between high-burden and low-burden informal caregivers. Method: The study population consisted of 423 caregivers

In this article we present a study of a new class of surfactants denoted as PEG1500-12-acyloxystearates, which have potential use as pharmaceutical solubilizers. These amphiphilic molecules present interesting properties with regard to cell damage effects. PEG1500-12-acyloxystearates with C-14 to C-16 acyloxy chains cause little or no damage to red blood and intestinal cells, whereas the surfactan

Arsenic (As) is one of the most important dangerous elements as more than 100 million of people are exposed to risk, globally. The permissible threshold of As for drinking water is 10 μg/L according to both the WHO’s drinking water guidelines and the Iranian national standard. However, several studies have indicated that As concentrations exceed this threshold value in several regions of Iran. Thi

Context: Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. Objectives: To evaluate the reliability and validity of symptom self-report in cancer outpatients with and without mild to moderate cognitive impairment. Methods: This was an analysi

Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study. Methods: Targeted mass spectrometry metabolomics

Background: The neurobiological origins of the early and predominant behavioral changes seen in the behavioral variant of Alzheimer’s disease (bvAD) remain unclear. A selective loss of Von Economo neurons (VENs) and phylogenetically related neurons have been observed in behavioral variant frontotemporal dementia (bvFTD) and several psychiatric diseases. Here, we assessed whether these specific neu

The resistivity method is an established geophysical method with a broad range of engineering and environmental applications. It has been tried numerous times on embankment dams, mainly for seepage investigations, dam status control and investigations of known defects. In previous use of the method on embankment dams some success has been reported, but only occasionally. The method is still not co

In 2010, Spence and Van Gelder presented a family of CNF formulas based on combinatorial block designs. They showed empirically that this construction yielded small instances that were orders of magnitude harder for state-of-the-art SAT solvers than other benchmarks of comparable size, but left open the problem of proving theoretical lower bounds. We establish that these formulas are exponentially

We present a Moiré method that can be used to investigate positional instabilities in a scanning hard x-ray microscope with nanometer precision. The development of diffractionlimited storage rings offering highly-brilliant synchrotron radiation and improvements of nanofocusing x-ray optics paves the way towards 3D nanotomography with 10 nm resolution or below. However, this trend demands improved

The incorporation of water isotopologues into the hydrology of general circulation models (GCMs) facilitates the comparison between modeled and measured proxy data in paleoclimate archives. However, the variability and drivers of measured and modeled water isotopologues, as well as the diversity of their representation in different models, are not well constrained. Improving our understanding of t