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PURPOSE The ESPAC4 trial showed that adjuvant chemotherapy with gemcitabine plus capecitabine (GemCap) produced longer overall survival (OS) than gemcitabine monotherapy. Subsequently, the PRODIGE24-CCTG PA.6 trial showed even longer survival for modified fluorouracil, folinic acid, irinotecan, and oxaliplatin (mFOLFIRINOX) than gemcitabine but had more restrictive eligibility criteria. Our aim wa
Background: Multi-country studies assessing the quality of maternal and newborn care (QMNC) during the COVID-19 pandemic, as defined by WHO Standards, are lacking.Methods: Women who gave birth in 12 countries of the WHO European Region from March 1, 2020 - March 15, 2021 answered an online questionnaire, including 40 WHO Standard-based Quality Measures.Findings: 21,027 mothers were included in the
Current knowledge of the molecular changes induced by dopamine denervation and subsequent treatment with L-DOPA is based on studies performed on relatively acute and young animal models of parkinsonism. It is highly warranted to ask how well these models simulate the state of chronic denervation and sustained L-DOPA pharmacotherapy which are typical of advanced Parkinson's disease. This study inve
BACKGROUND: Firefighting foam-contaminated ground water, which contains high levels of perfluoroalkyl substances (PFAS), is frequently found around airports. In 2018 it was detected that employees at a municipal airport in northern Sweden had been exposed to high levels of short-chain PFAS along with legacy PFAS (i.e., PFOA, PFHxS, and PFOS) through drinking water.OBJECTIVES: In this study, we aim
The objective of this study is to increase the knowledge regarding school principals’work situations by examining the associations between various factors and the school principals’assessments of their ability or wish to work until 65 years of age or longer. The 1356 participatingschool principals in this study were aged between 50 and 64 years of age. Individual and workfactors were evaluated in
To provide a complete portrayal of the multiple factors negatively impacting insects in agricultural landscapes it is necessary to assess the concurrent incidence, magnitude, and interactions among multiple stressors over substantial biogeographical scales. Trans-national ecological field investigations with wide-ranging stakeholders typically encounter numerous challenges during the design planni
PURPOSE: multiple myeloma is considered an incurable hematologic cancer but a subset of patients can achieve long-term remissions and survival. The present study examines the clinical features of long-term survival as it correlates to depth of disease response. PATIENTS & METHODS: this was a multi-institutional, international, retrospective analysis of high-dose melphalan-autologous stem cell
Abstract Title: More Than Money: Human and Social Capital in Financing Swedish Innovative Small Enterprises. Seminar Date: 03/06 - 2025 Course: Degree Project: New Venture Creation- Entrepreneurship and Innovation, Lund University School of Economics and Management, 15 ECTS Authors: Daniel Milde & Gustav Lingevik Supervisor: Joakim Winborg Keywords: Entrepreneurial finance, Human capital, Soci
Nu påbörjas årets lönerevision vid Luleå tekniska universitet som avser perioden 2024–10–01 –– 2025–09–30. Även i år har vi ett sifferlöst avtal. För medlemmar i Saco tillämpas på LTU lönesättande samtal vilket innebär att du som anställd i samband med lönerevisionen ska ha två samtal med din närmaste chef. Det första samtalet är tänkt att vara ett ömsesidigt utbyte av information avseende din pre
Asthma patients who continue to experience symptoms despite taking regular inhaled corticosteroids represent a management challenge. Leukotrienes play a key role in asthma pathophysiology, and since pro-inflammatory leukotrienes are poorly suppressed by corticosteroids it seems rational to add a leukotriene receptor antagonist (LTRA) when a low to moderate dose of inhaled corticosteroids does not
Page 1 University Admissions in Sweden FE 20102 839 87 Östersund Sweden . Notification of Selection Results International Master Programmes Autumn Semester 2016 2016-04-25 Application no. Personal code no. 8651496 19870404-T956 YANG LONG 19TH FLOOR, PRIME TOWER, 22 CHAOYANGMENWAI STREET, BEIJING, P.R 100020 BEIJING KINA Notification of Selection Results for the autumn semester 2016 You have receiv
https://www.luaccommodation.lu.se/sites/luaccommodation.lu.se/files/masterht16-application-long_yang.pdf - 2026-05-19
Bacteria can cause life-threatening infections, such as pneumonia, meningitis, or sepsis. Antibiotic therapy is a mainstay of treatment, although antimicrobial resistance has drastically increased over the years. Unfortunately, safe and effective vaccines against most pathogens have not yet been approved, and thus developing alternative treatments is important. We analyzed the efficiency of factor
Objective. There is an increased risk of gastrointestinal carcinoma and smoking-related diseases after partial gastrectomy for peptic ulcer disease. The purpose of this study was to evaluate long-term cancer incidence and mortality after parietal cell vagotomy (PCV), a surgical method with a low rate of side effects, but creating hypochlorhydria in the stomach mimicking long-term treatment with an
I takt med ökad nederbörd och urbanisering ökar risken för pluviala översvämningar i våra urbana miljöer som följd av den ökade effekten av klimatförändringar. En allvarlig konsekvens som följd av alltmer kraftiga nederbörd och skyfall är att den hydrauliska kapaciteten i ett befintligt dagvattenledningssystem är överbelastad, vilket kan leda till översvämning. Detta arbete syftade att belysa hur The number of flooding incidents in our urban cities and communities has increased drastically as a result of the increased effect of global warming in recent years. The probability of occurrence for heavy rainfalls and cloudburst events is higher, increasing the risks of pluvial flooding in urban areas. As a result of more frequent flooding, the hydraulic capacity of existing stormwater pipe syst
BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are persistent substances with surfactant and repellent properties. Municipal drinking water contaminated with PFAS had been distributed for decades to one third of households in Ronneby, Sweden. The source was firefighting foam used in a nearby airfield since the mid-1980s. Clean water was provided from December 16, 2013.AIMS: The purpose was
Breast cancer is the most common cancer among women and prevention strategies are needed to reduce incidence worldwide. A healthy lifestyle index score (HLIS) was generated to investigate the joint effect of modifiable lifestyle factors on postmenopausal breast cancer risk. The study included 242,918 postmenopausal women from the multinational European Prospective Investigation into Cancer and Nut
Objective: To determine whether TNF blockers increase tumour risk in patients with RA. Material and methods: The South Swedish Arthritis Treatment Group register (SSATG) comprises over 90% of anti-TNF treated patients with RA in the area. 757 patients treated with etanercept or infliximab included between 1 February 1999 and 31 December 2002 were identified. 800 patients with conventional antirheu
This essay will summarize and study existing theories and the recent developments regarding long-term incentive (LTI) plans in Swedish companies listed on Nasdaq OMX Stockholm. The underlying theory is the principal-agent problem that arises in public companies, which highlights the behavioural aspects of decision-making for employees in a managerial position. This study aims to provide evidence t
