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Molecular oxygen has been detected in the coma of comet 67P/Churyumov-Gerasimenko with a mean abundance of 3.80 ±0.85% by the ROSINA mass spectrometer on board the Rosetta spacecraft. To account for the presence of this species in comet 67P/Churyumov-Gerasimenko, it has been shown that the radiolysis of ice grain precursors of comets is a viable mechanism in low-density environments, such as molec
Acetylcholine (ACh) induces an Nω–nitro–L–arginine (L–NOARG)–resistant relaxation and hyperpolarization in the rat isolated hepatic artery. The possibility that carbon monoxide (CO) produced by haem oxygenase (HO) is an endogenous mediator of this response was investigated. Exogenously applied CO evoked a concentration–dependent relaxation, and the CO ‘scavenger’ oxyhaemoglobin (10μM) reduced the
Background Calcidiol insufficiency may accelerate the development of secondary hyperparathyroidism (SHPT). We tested the effect of a substantial increase in calcidiol on mineral metabolism in patients with chronic kidney disease (CKD). Methods Ninety-five patients with CKD Stages 3-4, parathyroid hormone (PTH) above 6.8 pmol/L and calcidiol below 75 nmol/L were randomized to receive either choleca
This presentation discusses an ongoing research project that aims to collect data about the practice of information search. It seeks to learn more about different ways in which tourist information is collected at different stages of a journey. Speaking to tourism planners and reading tourism research, it seems as if the digitalization of information has completely changed tourists’ information sea
Cross-cultural studies have found national differences in how concerned people are about online privacy. However, it has not yet been settled what causes this variation, and several factors have been proposed in the literature, including internet habituation, individualism, and uncertainty avoidance. Here we investigate these factors by two studies. In the first, we examine the association between
A novel energy management (EM) approach is introduced, integrating core elements of collective intelligence (CI) and reinforcement learning (RL) and called CIRLEM. It operates by distributing a flexibility signal from the energy supplier to agents within the grid, prompting their responsive actions. The flexibility signal reflects upon the collective behaviour of the agents in the grid and agents
Background: Patients with obesity have a higher risk of complications after total knee arthroplasty (TKA). We investigated the change in weight 1 and 2 years post-Bariatric Surgery (BS) in patients that had undergone both TKA and BS as well as the risk of revision after TKA based on if BS was performed before or after the TKA. Methods: Patients who had undergone BS within 2 years before or after T
In order to overcome the shortcomings of crash data a number of surrogate measures of safety have been developed and proposed by various researchers. One of the most widely used temporal indicators is time-to-collision (TTC) which requires the road users to be on a collision course. Road users that are strictly speaking not on a collision course actually might behave and take evasive actions as if
Hip fractures are a major health problem with high socio-economic costs. Subject-specific finite element (FE) models have been suggested to improve the fracture risk assessment, as compared to clinical tools based on areal bone mineral density, by adding an estimate of bone strength. Typically, such FE models are limited to estimate bone strength and possibly the fracture onset, but do not model t
Glyoxalase I (GlxI) is a member of the glyoxalasesystem, which is important in cell detoxification and convertshemithioacetals of methylglyoxal (a cytotoxic byproduct of sugarmetabolism that may react with DNA or proteins and introducenucleic acid strand breaks, elevated mutation frequencies, andstructural or functional changes of the proteins) and glutathioneinto D-lactate. GlxI accepts both the
Many normative theorists want to contribute to making the world a better place. In recent years, it has been suggested that to realise this ambition one must start with an adequate description of real-life practices. To determine what should be done, however, one must also fundamentally criticise existing moral beliefs. The method of reflective equilibrium offers a way of doing both. Yet, its prac
The main function of a membrane is to control the exchange of matter between the surrounding regions. As such, accurate modeling of membranes is important to properly describe their properties. In many cases in both biological systems and technical applications, the membranes are composite structures where transport properties may vary between the different sub-regions of the membrane. In this wor
This work is focused on synthesis, characterization, and determination of main parameters of the multilayer P123 templated TiO2 films. The mesoporous multilayer thin films consist of TiO2 nanoparticles on the F-doped SnO2 (FTO) conductive glass substrates. The films were grown by implementing the protocol of supramolecular templating with the amphiphilic triblock copolymer, Pluronic P123. The temp
The diversity and community composition of moths (both macro- and micromoths) at 32 sites, representing a wide range of habitat types (forests, grasslands, wetlands, agricultural and urban areas) within a restricted region in central Scania,southern-most Sweden, was investigated by use of light moth traps and compared with vascular plant species richness and habitat characteristics. The results re
Neurocognitive disorder encompasses many separate diagnoses, such as frontotemporal dementia (FTD), Alzheimer's disease (AD), Lewy body dementia (LBD), vascular dementia (VaD), and mixed dementia (MD). Because of the many variations between and within each subtype, it may be a challenge to clinically diagnose each condition. In a previous study on 176 dementia patients in a university hospital coh
The establishment of introduced species in new environments is today widely acknowledged as a potential threat to biodiversity, and many plants that are known to be invasive have obviously spread from gardens. Thus, in the context of biosecurity, we need to consider how contemporary gardeners think about which plants and animals are welcome in their gardens. In this chapter we look at vegetation i
Penetration of the viral genome into a host cell nucleus is critical for initiation of viral replication for most DNA viruses and a few RNA viruses. For herpesviruses, viral DNA ejection into a nucleus occurs when the capsid docks at the nuclear pore complex (NPC) basket with the correct orientation of the unique capsid portal vertex. It has been shown that capsid vertex-specific component (CVSC)
Landslides often cause significant casualties and economic losses, and therefore landslide susceptibility mapping (LSM) has become increasingly urgent and important. The potential of deep learning (DL) like convolutional neural networks (CNN) based on landslide causative factors has not been fully explored yet. The main target of this study is the investigation of a GIS-based LSM in Zanjan, Iran a
