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To improve gas turbine performance, the operating temperature has been increased continuously. However, the heat transferred to the turbine blade is substantially increased as the turbine inlet temperature is increased. Cooling methods are therefore needed for the turbine blades to ensure a long durability and safe operation. The blade tip region is exposed to the hot gas flow and is difficult to
Popular Abstract in Swedish Allt liv på jorden har utvecklats i en vattenbaserad miljö. Proteiner och andra biomolekyler har därigenom anpassats i sin struktur och funktion till vattnets speciella egenskaper. För att kunna förstå biologiska processer måste vi studera hur biomolekyler växelverkar med det omgivande vattnet under fysiologiska betingelser. Detta är särkilt viktigt eftersom det flesta The results presented in this thesis demonstrate that the magnetic relaxation dispersion (MRD) technique can provide information of relevance to protein biophysics, magnetic resonance imaging and cell biology. By immobilizing proteins with covalent cross-links, intermittent protein dynamics on the previously inaccessible ns-µs time scale could be probed with MRD via the exchange of water molecule
In the aftermath of the nuclear weapons testing and as compared with agriculture, the forest industry has received relatively little attention in spite of its large-scale use of radiocesium- contaminated wood and water. After the Chernobyl nuclear power plant accident in 1986, numerous studies of the forest environment have been conducted with respect to radionuclide transfer through the forest ec
Several studies have reported that spontaneous eye movements occur with visual imagery and that they closely reflect content and spatial relations from an original picture or scene (e.g., Brandt & Stark, 1997; Spivey & Geng, 2001; Johansson, Holsanova, & Holmqvist, 2006). Nevertheless, the exact purpose of these eye movements to “nothing” is elusive and has currently been the target of
Alcohol intoxication is the cause of many falls requiring emergency care. The control of upright standing balance is complex and comprises contributions from several partly independent mechanisms like coordination, feedback and feedforward control and adaptation. Analysis of the segmental body movement coordination offers one option to detect the severity of balance problems. The study aims were (
Health status and functional profile at admission of nursing home residents in Iceland over 11-year period. International Journal of Older People Nursing doi: 10.1111/j.1748-3743.2011.00287.x Background. The knowledge over time of the health status and changes in care needs of newly admitted nursing home residents is limited. Objectives. To investigate trends in residents' health status and functi
OBJECTIVES: This study investigated exposure- and subject-related determinants of annoyance and performance during the chemical odor provocation of healthy persons with self-reported environmental annoyance. METHODS: Persons with self-reported annoyance attributed to (i) chemicals or smells (smell-annoyed, SA, N=29), (ii) electrical equipment (electrically annoyed, EA, N= 16), and (iii) both smell
Abstract in UndeterminedStrategic recollection refers to control processes that allow the retrieval of information that is relevant for a specific situation. These processes can be studied in memory exclusion tasks, which require the retrieval of particular kinds of episodic information. In the current study, we investigated strategic recollection in reality monitoring by event-related potentials
Popular Abstract in Swedish Denna avhandling är inriktad på metoder för att förbättra och utvärdera infrastrukturer för geografiska data (eng. Spatial Data Infrastructure). Syftet har varit trefaldigt: att utveckla ett ramverk för hantering och utvärdering av en infrastruktur, att förbättra tillgängligheten av geografiska data i en infrastruktur, och för att förbättra kartografi i visningstjänsterThis thesis mainly focuses on methods for improving and evaluating Spatial Data Infrastructures (SDIs). The aim has been threefold: to develop a framework for the management and evaluation of an SDI, to improve the accessibility of spatial data in an SDI, and to improve the cartography in view services in an SDI. Spatial Data Infrastructure has been identified as an umbrella covering spatial data
Popular Abstract in Swedish Studier av enstaka makromolekyler gör det möjligt att få insikt i och karakterisera viktiga biologiska processer. DNA, livets molekyl, är av särskilt intresse här. I denna avhandling användar vi metoder från statistisk fysik för att studera olika aspekter av DNA i nanokanaler och dess smältegenskaper. DNA-smältning är inte bara relevant för förståelsen av denna molekylsInvestigation of single macromolecules makes it possible to gain insight into and characterize important biological processes. DNA as the molecule of life is of special interest here. In this thesis tools from statistical physics are used to study different aspects of DNA confined to nanochannels, with particular regard to its denaturation properties. The study of DNA melting from the theoretical
Turbulent non-premixed flames with local extinction and re-ignition exhibit multiple combustion modes including ignition waves, diffusion flames, partially premixed flames, and ignition-assisted partially premixed flames. The mechanisms of local extinction and re-ignition are not well understood and numerical modeling of multi-mode combustion is a challenging task. In this work, a specially design
The rapid pace of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) pandemic presents challenges to the real-time collection of population-scale data to inform near-term public health needs as well as future investigations. We established the COronavirus Pandemic Epidemiology (COPE) consortium to address this unprecedented crisis on behalf of the epidemiology research comm
In 2019 October Betelgeuse began a decline in V-band brightness that went beyond the minimum expected from its quasi-periodic ∼420 day cycle, becoming the faintest in recorded photometric history. Observations obtained in 2019 December with Very Large Telescope/SPHERE have shown that the southern half of the star has become markedly fainter than in 2019 January, indicating that a major change has
The method of using short laser and X-ray pulses to investigate dynamics in materials (pump-probe) has been used for several decades. This thesis presents work that was carried out using these sources of light to reveal acoustic, thermal and non-thermal dynamics. The dynamics were induced in the samples by depositing energy with a pulsed laser, and probed with X-ray diffraction. The recent increas
As a consequence of heightened concern for the greenhouse effect, depleting oil reserves and skyrocketing oil prices, renewable fuels, Such as bioethanol, are becoming increasingly important. Cellulosic biomass like wood, agricultural residue and herbaceous material is a huge, cheap natural resource that can be used for ethanol production. Decreasing production costs through technological developm
Mantle cell lymphoma (MCL) is believed to originate from a naive B cell. However, we recently demonstrated that a subset of MCL displayed mutated V-H genes. We also reported restricted use of certain V-H genes. To assess the prognostic impact of these new findings, we performed V-H gene analysis of 110 patients, revealing that 18 (16%) patients had mutated and 92 (84%) patients had unmutated V-H g
BACKGROUND: The IFCC Reference Measurement System for hemoglobin (Hb)A(1)c (IFCC-RM) has been developed within the framework of metrologic traceability and is embedded in a network of 14 reference laboratories. This paper describes the outcome of 12 intercomparison studies (periodic evaluations to control essential elements of the IFCC-RM). METHODS: Each study included: unknown samples (to test in
During the breeding of our major crop plants for high yield and edibility, several desirable traits, including resistance to pest insects, have been lost (Gatehouse et al., 1991). Genetic engineering is now vigorously seeking to reinsert such genes into crop plants, making them toxic or less palatable for herbivorous pests. One class of inhibitors under study are protease/proteinase inhibitors. Th
