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The long-term cognitive outcomes of Alzheimer’s disease — influence of APOE genotype, NSAID therapy, and cholinesterase inhibitor treatment.

Introduction: Heterogeneity in cognitive outcomes and response to treatment has been described in Alzheimer’s disease (AD). Using the method of mixed models, higher resolution can be obtained to identify potential predictors of long-term outcomes. Aims: To analyse the impact of the APOE genotype, non-steroidal anti-inflammatory drug (NSAID) therapy and cholinesterase inhibitor treatment (ChEI) on

Indoor air temperatures, CO2 concentrations and ventilation rates : Long-term measurements in newly built low-energy schools in Sweden

Within a period of ten years a large number of schools need to be built in Sweden and these new schools need to be nearly zero energy buildings. School classrooms are required to provide healthy learning environments to help children perceive and process information. This means that classrooms must provide adequate levels of indoor air quality and thermal comfort. This article investigates CO2 con

Trajectories of maternal symptoms of posttraumatic stress disorder predict long-term mental health of children following the Wenchuan earthquake in China : A 10-year follow-up study

Background: Maternal psychopathology can be an important factor associated with psychological adjustment of children. However, there is limited research on long-term impacts of maternal posttraumatic stress disorder (PTSD) on children's mental health. This study examined how PTSD trajectories of women exposed to the 2008 Wenchuan earthquake in China predicted their children's mental health symptom

Doing Normalcy. Attractive interactions for teenage boys with disabilities

The contemporary expansion of diagnoses is a well-known phenomenon. What is rarely investigated, however, are people’s subtle ways of deconstructing medical stigmas in everyday interactions. This article, based on an ethnographic study of a recreational activity for teenage boys with diverse diagnoses and disabilities (for instance, Asperger’s syndrome, ADHD, and cerebral pares), shows how a de-st

Differences in biomarker concentrations and predictions of long-term outcome in patients with ST-elevation and non-ST-elevation myocardial infarction

Background: Differences in biomarkers reflective of pathobiology and prognosis between ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) are incompletely understood and may offer insights for tailoring of treatment. Methods: This registry-based study included 538 STEMI and 544 NSTEMI patients admitted 2008–2014. Blood samples were collected day 1–3 afte

Quality of Life Among People with Psychiatric Disabilities : Does Day Centre Attendance Make a Difference?

The purpose was to investigate (i) how people with psychiatric disabilities who attend day centres experience their quality of life (QoL) compared to non-attendees, (ii) differences in QoL between those who attend meeting place-oriented centres and those who attend work-oriented centres, (iii) possible correlates of QoL among day centre attendees. Ninety-three day centre attendees and 82 non-atten

Dietary manipulation of the sow milk does not influence the lipid absorption capacity of the progeny

A control diet without supplemental fat and four diets containing 8% of coconut oil, rapeseed oil, fish oil or sunflower oil were fed to lactating sows in order to investigate the lipid absorption capacity of their progeny in terms of pancreatic enzyme activity, hormonal regulation, and bile salt concentration. In addition, the effect of age was studied during the four week suckling period, and du

Just because it’s disgusting does make it more wrong: Level of disgust affects moral judgment.

Three experiments were conducted to investigate the impact of affect on moral judgment. Participants read stories describing morally questionable actions and made judgments of wrongness. Judgments were affected by morally irrelevant disgust, and the effect was moderated by individual differences in disgust sensitivity and preferred processing mode. More specifically, the effect was stronger for pa

Ultrafast Dynamics of Long Homologues of Carotenoid Zeaxanthin

Three zeaxanthin homologues with conjugation lengths N of 15, 19, and 23 denoted as Z15, Z19, and Z23 were studied by femtosecond transient absorption spectroscopy, and the results were compared to those obtained for zeaxanthin (Z11). The energies of S2 decrease from 20 450 cm(-1) (Z11) to 18 280 cm(-1) (Z15), 17?095 cm(-1) (Z19), and 16?560 cm(-1) (Z23). Fitting the N dependence of the S-2 energi

What do we know about hybridization among bryophytes in nature?

Despite being recognized as a widespread and evolutionary important phenomenon among vascular plants, interspecific hybridization among bryophytes has been strongly underestimated. In the present review, we summarize knowledge about bryophyte hybrids that are found in nature. Mechanisms of reproductive isolation in bryophytes are compared with those in vascular plants. The morphological and geneti

Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity.

The effect of a quinoline-3-carboxamide on the T-cell-dependent B-cell response was investigated in C57BL/6 mice after NP-CGG immunization. The primary serum response to the hapten was slightly inhibited by treatment with a quinoline-3-carboxamide. This inhibition was paralleled by reduced numbers of germinal center B cells and follicular T cells in the spleen up to 21 days after immunization. Als

The short rotators do not influence capsular compliance or pain in severe hip osteoarthritis. A randomised controlled trial.

Abstract: A randomised controlled trial was performed to investigate if the short rotators affected the compliance of the capsule in osteoarthritis (OA). 68 OA patients admitted for total hip arthroplasty (THA) were randomised to have their compliance estimated during surgery with either their short rotators intact or released. Radiographic severity of OA, range of motion and pain were assessed in

How do We make a We

Curated by Claudia De la Torre and Gregorio Magnani in collaboration with the participants of the 23th edition CSAV - Artists’ Research Laboratory, the publication reflects on the experiences shared at the laboratory and on its overall theme. Through individual and collaborative contributions it investigates how sound, performance, and language may become tools in the creation of a “we” capable of