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Nils Wohlin and the question of inheritance patternsIt has long been assumed that inheritance patterns varied strongly betweendifferent regions. In the early 20th century statistician Nils Wohlin made afamous account of Swedish inheritance patterns, claiming significant differences between Swedish provinces, especially between eastern and western Sweden. Newer studies of inheritance patterns have
Marine endotherms in the polar regions face a formidable thermal challenge when swimming in cold water. Hence, they use morphological (fat, blubber) adjustment and peripheral vasoconstriction to reduce demands for heat production in water. The animals then regain normothermia when resting ashore. In the king penguin (Aptenodytes patagonicus) metabolic rate is lower in fed than in fasted individual
Malignant pleural mesothelioma is an aggressive cancer with poor prognosis. Here we have investigated in vitro efficacy of BAMLET and BLAGLET complexes (anti-cancer complexes consisting of oleic acid and bovine α-lactalbumin or β-lactoglobulin respectively) in killing mesothelioma cells, determined BAMLET and BLAGLET structures, and investigated possible biological mechanisms. We performed cell vi
Immunophenotypic characterization and molecular analysis have long been used to delineate heterogeneity and define distinct cell populations. FACS is inherently a single-cell assay, however prior to molecular analysis, the target cells are often prospectively isolated in bulk, thereby losing single-cell resolution. Single-cell gene expression analysis provides a means to understand molecular diffe
Neural stem cell lines represent a homogeneous source of cells for genetic, developmental, and gene transfer and repair studies in the nervous system. Since both gene transfer of neurotrophic factors and cell replacement strategies are of immediate interest for therapeutical purposes, we have generated BDNF-secreting neural stem cell lines and investigated to what extent different endogenous level
In the mid-19th century, the discovery that bone microstructure in fossils could be preserved with fidelity provided a new avenue for understanding the evolution, function, and physiology of long extinct organisms. This resulted in the establishment of paleohistology as a subdiscipline of vertebrate paleontology, which has contributed greatly to our current understanding of dinosaurs as living org
One of the primary objectives in forensic psychiatry, distinguishing it from other psychiatric disciplines, is risk management. Assessments of the risk of criminal recidivism are performed on a routine basis, as a baseline for risk management for populations involved in the criminal justice system. However, the risk assessment tools available to clinical practice are limited in their ability to pr
The stability of dispersions containing charged particles may obviously be regulated by salt. In some systems, the effective charge, as measured by the potential some small distance away from the particles, can have a sign opposite to the bare surface charge. If charge reversal takes place, there is typically a salt concentration regime within which colloidal stability increases with added salt. T
Phthalates are widespread contaminants with differing chemical characteristics, which largely determine their product applications, and they can leach into the environment. Due to their endocrine disruptive properties at long-term low-level exposure, they propose a health threat to people that has been associated with several adverse health effects such as: decreased male fertility and impacts on
Europeiska unionen syftar till att skapa fri handel på en inre marknad. Det innebär en fri rörlighet av bland annat varor. Med varor avses alla materiella ting, vilket även inkluderar avfall. Handel med avfall mellan Europeiska unionen och tredje länder är också vanligt förekommande. Anledningen till att handel bedrivs med avfall är att vissa avfallskategorier fungerar som insatsvaror i produktionThe European Union aims to create free trade on an internal market. Among other things, this means free movement of goods. Goods are defined as all material things, which also include waste. Trade in waste between the European Union and third countries is also common. The reason for trading in waste is that certain waste categories act as inputs in the production of other goods and products. A com
Den samiska ursprungsbefolkningens traditionella territorium breder ut sig över delar av Sverige, Norge, Finland och Ryssland. Samisk kultur är starkt kopplad till rennäringen, som kräver vidsträckta och sammanhängande marker där renen ostörd kan få tillgång till naturbete. Den här uppsatsen undersöker nuvarande möjligheter för samer i Sverige att påverka beslutsprocesser rörande användning av marThe traditional territory of the indigenous Sami people stretches into Sweden, Norway, Finland and Russia. Sami culture is strongly connected to reindeer husbandry, which requires vast and coherent land where the reindeer can access natural pasture without disturbances. This thesis examines present possibilities for Sami in Sweden to impact decision-making processes regarding use of land and natur
Introduction. Bread is one of the most consumed foods in the world today. It is also the cause for major food waste streams. Most breads have turned into high glycaemic index products with low nutritional value. This master’s thesis investigated whether the soluble oat fiber ß-glucan (BG) would have positive effects on the abovementioned. There are health claims associated with different doses of
Numerous broad insights have emerged in the last decades concerning the invasive non-indigenous round goby (Neogobius melanostomus) and its expanding presence in the Baltic Sea. The waters surrounding the Danish isles are the final frontiers separating the Baltic Sea from the North Sea, and although they offer highly favourable habitats, the biotic resistance in Öresund by native competitors might
Målsättningen att minska koldioxidutsläppen i världen har lett till en ökad efterfrågan på elbilar. Elbilar ses som en nyckelfaktor för EU:s omställning till en klimatneutral ekonomi. Det ökar efterfrågan på nödvändiga råvaror till elbilsbatterier som EU vill trygga tillgången på. För det ändamålet har kommissionen tagit fram en handlingsplan om batterier. Handlingsplanen om batterier identifierarThe goal of reducing carbon dioxide emissions in the world has led to increased demand for electric cars. Electric cars are seen as a key factor for the EU's transition to a climate-neutral economy. This increases the demand for the necessary raw materials for electric car batteries, which the EU wants to secure access to. To this end, the Commission has drawn up an action plan on batteries. T
Det föreligger ett samhälleligt behov av en effektiv brottsbekämpning till skydd för samhällsmedborgarna. Effektiv brottsbekämpning upprätthålls genom de brottsbekämpande myndigheterna som har diverse möjligheter att bedriva verksamheten på. En av möjligheterna är användningen av hemliga tvångsmedel. Hemliga tvångsmedel är åtgärder som innebär att en misstänkt person övervakas eller avlyssnas, utaThere is a societal need for effective law enforcement to protect citizens. Effective law enforcement is maintained through the law enforcement authorities, which have various opportunities to conduct business. One of the possibilities is the use of secret coercive measures. Secret coercive measures are measures that involve a suspect being monitored or intercepted without consent. However, it is
The freshwater pearl mussel Margaritifera margaritifera has dramatically declined through its entire distribution range since the 1900’s. Despite the increasing conservation measures implemented to protect the species, many populations are still endangered. The long-term objective of this research, realized in collaboration with Lund University and the Life Connects project, was to raise the succe
Rapporter om rekordlåga grundvattennivåer och införda vattningsförbud blir vanligare och vanligare. En av de kommuner som har haft problem med dricksvattenförsörjningen är Gävle kommun. De har, via ett samarbetsorgan, anlitat Midvatten AB för att kartlägga förutsättningar för att inrätta en ny dricksvattentäkt i Älvkarleby-Skutskär. I det aktuella området löper Uppsalaåsen, som innehåller mycket gSweden has in recent years suffered record-low groundwater levels with imposed water restrictions. One of the municipalities who have had problems with their drinking-water supply is Gävle. They have hired Midvatten AB to review a possible location that for groundwater extraction in Älvkarleby-Skutskär. The Uppsala Esker, which contains a lot of groundwater, passes through the area. Parallel to th
In recent years, the office market has been changing, mainly due to the Covid-19 pandemic and technological innovation. This has impacted how office space is used and has led to an increase in the range of available real estate products. One of the decisions organizations need to make is whether to own or lease their space, which is a decision driven by several parameters. The right decision for a
Stroke remains a leading cause of long-term disability worldwide, making effective recovery critical for minimizing residual impairments. Given the limited scope of pharmacological interventions in the post-stroke recovery phase, effective non-pharmacological strategies are essential for supporting better prognosis. One experimental approach to enhancing recovery in rodent models is environmental
