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The “acidic mantle” of the skin surface has been related to several essential functions of the skin, although the origin of the acidity is still obscure. In this paper, we investigate how different transport processes can influence the local proton concentration inside a membrane consisting of oriented lipid bilayers. This system is chosen as a simple model of the extracellular lipids in the upper
This study presents how a TiO2(B) film exposing the (001) face can be grown on Au(111) by chemical vapor deposition. Identification and characterization of the TiO2(B)(001) layer are carried out with low-energy electron diffraction (LEED), synchrotron radiation photoelectron spectroscopy (PES), scanning tunneling microscopy (STM) and X-ray absorption spectroscopy (XAS). Formation of the TiO2(B) fi
Gut enzymes in the small intestine are exposed to extremely low electrical currents (ELEC) generated by the smooth muscle. In the present study, the in vitro tests were undertaken to evaluate the effect of these electric currents on the activity of the proteolytic pancreatic digestive enzymes. A simulator generating the typical electrical activity of pig gut was used for these studies. The electri
About 8000 Swedish women are diagnosed with breast cancer each year, and around 1500 die from the disease. Triple-negative breast cancer (TNBC) constitutes 7-14% of all breast cancer and is characterized by an aggressive phenotype with poor prognosis and no targeted therapy available. The aim of this thesis was to evaluate new potential prognostic biomarkers in breast cancer, and with special focu
Modern power system is a complex dynamical system and one of the largest man-made systems. With recent driving forces like environmental concerns over air emissions, the modern power system is evolving towards an even more complex system. So it is necessary to handle the current challenges in power systems with simple approaches and avoid adding further complexity as much as possible. Also the imp
X-ray scattering imaging can provide complementary information to conventional absorption based radiographic imaging about the unresolved microstructures of a sample. The scattering signal can be accessed with various methods based on coherent illumination, which span from self-imaging to speckle scanning. The directional sensitivity of the existing real space imaging methods is limited to a few d
Avhandlingen, som består av fyra delstudier, är en femårsuppföljning av kvinnliga missbrukare, som var tvångsomhändertagna på Lunden mellan januari 1997 och december 2000, och som genomgick en omfattande utredning. Klienterna har systematiskt utretts med psykologiska och neuropsykologiska test i samarbete med personal och Lundens psykiater. Test och skattningsskalor som använts är standardiserade The study focus is a sample of women with drug dependence admitted to compulsory treatment according to the Swedish act of care for drug abusers (LVM, 1988:870) and according to the act of care for young persons (LVU, 1990:52). From a cohort consecutively admitted to residential treatment at Lunden between 1997 and 2000, a sample of 132 women was selected for a five year follow-up. They were evalu
Indoor positioning is recognized as one of the upcoming major applications which can be used in wide variety of applications such as indoor navigation and enterprise asset tracking. The significance of localization in indoor environments have made the use of Wi-Fi based indoor positioning so that it can utilize available current wireless infrastructure and perform positioning very easily. In this
This article outlines a potential synergy between sustainability and well-being research. Currently aims within well-being and sustainability research focus on increasing well-being. First, sustainability is defined and important concepts within it highlighted, that is, aims, interdependencies, constraints, values and balanced adaptive processes. It is suggested that positioning well-being more cl
The protonation status of key residues and bound ligands are often important for the function of a protein. Unfortunately, protons are not discerned in normal protein crystal structures, so their positions have to be determined by more indirect methods. We show that the recently developed quantum refinement method can be used to determine the position of protons in crystal structures. By replacing
During pregnancy and lactation, changes occur in a variety of factors which have great potential to influence bone mineral density (BMD). Smoking habits, the level of alcohol consumption, the level of physical activity, body weight, soft tissue composition and hormone levels are all factors that change during the course of these conditions. Some of these factors are capable of increasing BMD, and
Emphysema and liver cirrhosis can be caused by the Z mutation (Glu342Lys) in the serine protease inhibitor alpha 1-antitrypsin (alpha 1AT), which is found in more than 4% of the Northern European population. Homozygotes experience deficiency in the lung concomitantly with a massive accumulation of polymers within hepatocytes, causing their destruction. Recently, it was proposed that Z-alpha 1AT po
In the microelectronics industry, gold electrodes on silicon dioxide are produced using an adhesive layer of chromium or titanium. This method is applicable whenever a dry environment is present. However, when such an electrode is exposed to an electrolyte a galvanic cell is formed and the less noble metal will dissolve and eventually destroy the electrode. We describe here how a monolayer of merc
The purpose of this study was to investigate for how long the thermal power of hydration can be measured with isothermal calorimetry, which is a general measurement technique with stable properties that, in many cases, can detect low rates of processes. Measurements were conducted for 365 days on cement paste with Portland cement, fly ash blended Portland cement and different water-to-binder ratio
We study the convergence of a semidiscrete scheme for the forward-backward parabolic equation ut = (W?(ux))x with periodic boundary conditions in one space dimension, where W is a standard double-well potential. We characterize the equation satised by the limit of the discretized solutions as the grid size goes to zero. Using an approximation argument, we show that it is possible to flow initial d
