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Objective: We aimed to study the association between neighborhood socioeconomic status at the age of 40 years and risk of ischemic stroke before the age of 50 years. Methods: All individuals in Sweden were included if their 40th birthday occurred between 1998 and 2010. National registers were used to categorize neighborhood socioeconomic status into high, middle, and low and to retrieve informatio

We determine Mg abundances in six Gaia benchmark stars using theoretical one-dimensional (1D) hydrostatic model atmospheres, as well as temporally and spatially averaged three-dimensional (〈3D〉) model atmospheres. The stars cover a range of Teff from 4700 to 6500 K, log g from 1.6 to 4.4 dex, and [Fe H] from -3.0 dex to solar. Spectrum synthesis calculations are performed in local thermodynamic eq

OBJECTIVE: Treatments have failed to delay or stop the autoimmune process, preceding onset of type 1 diabetes. We investigated if autoantigen-specific treatment with alum-formulated glutamate decarboxylase (GAD-Alum) was safe and affected progression to type 1 diabetes in children with islet autoimmunity.METHODS: In an investigator-initiated, double-blind, placebo-controlled clinical trial, non-di

Objective: Prospectively monitor how treatment of acutely ruptured anterior cruciate ligament (ACL) affects biomarkers of inflammation and proteolytic degradation over 5 years. Design: We studied 119 subjects with acute ACL injury from the randomized controlled knee anterior cruciate ligament, non-surgical versus surgical treatment (KANON)-trial (Clinical trial ISRCTN 84752559) who had synovial fl

Laser-induced photofragmentation fluorescence has been investigated for the imaging of alkali compounds in premixed laminar methane–air flames. An ArF excimer laser, providing pulses of wavelength 193 nm, was used to photodissociate KCl, KOH, and NaCl molecules in the post-flame region and fluorescence from the excited atomic alkali fragment was detected. Fluorescence emission spectra showed disti

OBJECTIVE:: Arterial stiffening increases with age and is associated with increased cardiovascular risk. Several risk factors have been shown to predict the development of arterial stiffening; however, a positive family history (FH+) of cardiometabolic disease (CMD) and hypertension has not been extensively studied. We hypothesize that FH+ of CMD plays a significant role in the development of arte

Partially premixed combustion (PPC) is used to meet the increasing demands of emission legislation and to improve fuel efficiency. With gasoline fuels, PPC has the advantage of a longer premixed duration of the fuel/air mixture, which prevents soot formation. In addition, the overall combustion stability can be increased with a longer ignition delay, providing proper fuel injection strategies. In

In this article, the convergence of quantum mechanical (QM) free-energy simulations based on molecular dynamics simulations at the molecular mechanics (MM) level has been investigated. We have estimated relative free energies for the binding of nine cyclic carboxylate ligands to the octa-acid deep-cavity host, including the host, the ligand, and all water molecules within 4.5 Å of the ligand in th

A phenomenological model for simulating the photoplethysmogram (PPG) during atrial fibrillation (AF) is proposed. The simulated PPG is solely based on RR interval information, and, therefore, any annotated ECG database can be used to model sinus rhythm, AF, or rhythms with premature beats. A PPG pulse is modeled by a linear combination of a log-normal and two Gaussian waveforms. The model PPG is o

Background. Trust is a complex concept, difficult to study, but very important in a patient-family physician relationship. One of the measures used to assess interpersonal trust is a scale developed by Anderson & Dedrick entitled the Trust in Physician Scale (TI PS). Objectives. The aim of the study was to assess the TI PS properties in relation to the age, gender, and health status of primary

To what extent have public policies contributed to the innovation performance of Finland and Sweden in the period 1970-2013? This paper aims to assess the share of innovations stimulated by the public sector, specifically because of receiving public funding or being the result of research collaboration with public institutions. We combine survey and LBIO results on these variables, to overcome rep

BACKGROUND: High reproducibility of test measurements is often considered an indication of high reliability of test results. The aim of the current study was to analyse the role of the traditional perimetric reliability indices, False Negative and False Positive responses, and Fixation Losses, as indicators of test reliability in comparison with threshold reproducibility in patients with suspect o

The purpose of this essay is to examine the ideas that are prominent in the Swedish disability policy regarding the stated goal of equal participation in society for all. In order to achieve this, I have chosen to focus on two documents, they are SOU 1982:46 Handlingsprogram i handikappfrågor and Prop. 2016/17:188 Nationellt mål och inriktning för funktionshinderspolitiken. I have examined these t

En ny akustisk infångningsenhet med kraftigt ökad kapacitet kan anrika nanopartiklar från kroppsvätskor. Det finns otroligt mycket information att utvinna ur biologiska vätskor som blod och urin. Biomolekyler som proteiner, blodkroppar och RNA kan säga väldigt mycket om en patients hälsa. Denna information är därför väldigt användbar för läkare när de ska sätta diagnoser, men för att få ut någonThis thesis outlines the design and construction of an acoustophoretic trapping device with greatly increased capacity and throughput, compared to current commercial systems. In acoustic trapping, a strong, localised acoustic field is generated inside a channel. This field can capture and retain particles against a flow, allowing for nanoparticle purification and enrichment without the need for ul

In past years, the demand for an indirect extraction of respiration and the interest in a joint study of respiratory and cardiac systems represented the driving forces for the development of Electrocardiogram Derived Respiration (EDR) algorithms. The main advantage of them consists in deriving a sufficiently reliable surrogate respiratory signal by only exploiting the normal electrocardiogram (ECG

Det är väl känt att kolmonoxid (CO) är en giftig och hälsofarlig gas som är luktlös, färglös och smaklös vilket gör den svår att detektera utan analytisk utrustning. Men under senaste åren så har forskning bevisat att i små doser så kan kolmonoxid användas som en terapeutisk substans för att lindra malaria, cancer, lung-, hjärt- och kärlsjukdomar men även reducera mängden inflammatoriska substanseIt is well known that Carbon monoxide is a toxic and hazardous gas, but during recent years it has been proven that using a controlled concentration, carbon monoxide can in fact be used as a therapeutic agent, and can contribute to decrease malaria, treat cardiovascular and lung diseases and potentially even treat cancer, among other things. The main problem in using carbon monoxide directly is th

There is no consensus on how to define and measure green growth. Consequently, we can neither state if growth is actually green nor econometrically explore important questions such as what determines green growth. This thesis takes a three-step approach to move one step closer to a unifying longitudinal cross-country measure of green growth. It analyzes how green growth has been quantitatively mea

Vi lever i en värld där många människor inte har tillgång till rent vatten och faktorer som torka, föroreningar och ett dåligt vattenförvaltningssystem påverkar detta. På grund av sociala, politiska och ekonomiska faktorer, så är det också komplicerat för dessa människor att vara med i beslutsprocesser som kan påverkar deras tillgång till vatten. Men vad skulle hända om man kombinerade två olika vWater-related issues such as drought and water scarcity are problems that many countries around the world are facing. To solve this, multiple efforts have been made to combat these problems such as adopting Integrated Water Resource Management (IWRM) as a management approach. IWRM is a holistic approach that links different water systems and has therefore been popularized and conceptualized by man