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Whole grain cereal products and baseline gut microbiota composition in metabolic and appetite regulation in healthy humans - Emphasizing rye and barley

The prevalence of obesity, type 2 diabetes (T2D) and cardiovascular disease (CVD) is increasing continuously worldwide. These metabolic diseases are associated with many health issues, including increased risk of depression and cognitive impairment. Whole grain (WG) has shown potential to prevent obesity, T2D and CVD. One mechanism can be related to gut fermentation of specific indigestible carboh

Development and Characterization of a Global Brain Ischemia Model in the Mouse -A Genetic and Pharmacological Approach

Popular Abstract in Swedish Hjärnskador som uppstår till följd av otillräckligt blodflöde (ischemi) drabbar årligen ett stort antal människor i Sverige och leder antingen till död eller invaliditet och åsamkar stort lidande för den drabbade och dennes anhöriga. Den vanligaste orsaken till hjärnischemi är stroke (slaganfall), som beror på en propp i ett blodkärl eller en hjärnblödning, till en begrBrain ischemia is a major cause of death and morbidity in the industrialized countries. It is mainly caused by stroke, but may also be the consequence of successful cardiopulmonary resuscitation in victims of cardiac arrest, known as transient global ischemia. Although extensive effort in the field of brain research using experimental rodent models, no neuroprotective treatments are at present ava

Development and Applications of Detailed Kinetic Models for the Soot Particle Size Distribution Function

Two different mathematical methods of implementing a detailed kinetic soot model have been employed in this work. The theoretical description of the soot modeling employed in this work is divided into three parts. Initially a detailed kinetic soot model is described from a chemistry and physics perspective. The soot model is then elaborated into mathematical form, starting with the formulation of

Inclusive Entrepreneurship Ecosystem Analysis in Montenegro

This report applies the International Labour Organization´s (ILO) inclusive entrepreneurship ecosystem approach to Montenegro and outlines the possibilities for a more inclusive and sustainable ecosystem that works for all. The application of the ILO´s approach led to a comprenhensive and holistic analysis of the Montenegrin ecosystem, which was followed by clear guidance on how the ecosystem of M

Assessing the Inventiveness of Bio-Pharmaceuticals under European and US Patent Law - A comparative study with special emphasis on DNA- and protein-related inventions

“The implications and applications of biotechnology continue to be at the centre of public debate. In the light of rapid scientific advances and novel insights, the multi-faceted discussions are particularly fierce with regard to patents on DNA–related technology. In the often very emotionally-led debate basically two directly conflicting schools of thoughts can be identified. Some people believe

Universell jurisdiktion i Sverige - Om regelsystemet som möjliggör och begränsar utövning av universell jurisdiktion i svensk rätt

Universalitetsprincipen utgör en jurisdiktionsgrund enligt svensk rätt. I slutet av år 2022 meddelade Högsta domstolen ett prejudicerande beslut som behandlade hur universell jurisdiktion ska förstås enligt svensk rätt. Högsta domstolen fastslog i detta fall bland annat att den misstänkte måste ha en tillräcklig anknytning till Sverige för att det ska finnas ett svenskt rättskipningsintresse vid uThe principle of universality constitutes a basis for jurisdiction under Swedish law. At the end of 2022, the Supreme Court delivered a precedent- setting decision dealing with how universal jurisdiction should be interpreted according to Swedish law. The Supreme Court determined that for Swedish courts to exercise universal jurisdiction, there has to be a Swedish judicial interest, which is decid

Developing a programmable mRNA pseudouridylation system to monitor gene-specific translation in human cells

A guide in the darkness; A system shedding light on mRNA pseudouridylation by PUS7 Proteins, the building blocks of life, are produced from messenger RNA (mRNA). mRNA is built by four ribonucleotides, namely adenine (A), guanine (G), cytosine (C) and uridine (U). Interestingly, RNA includes also chemically modified versions of the above nucleotides affecting many physiological processes. The most

Modelling of reservoir quality in quartz-rich sandstones of the Lower Cretaceous Bentheim sandstones, Lower Saxony Basin, NW Germany

Popular summary: Hydrocarbons, ground water and economic minerals occur in pores (voids) between sediment grains, which later may form more solid and less porous sedimentary rocks. Thus porosity is a term that describes the abundance of these pores and can be defined as the quantity of oil, gas, water and economic minerals a rock can hold and it is expressed as percentages (%). The other importa

Protein engineering and characterization of the blue mussel β-mannanase

Enzyme engineering for a better future It is essential for many organisms on this planet to be able to digest plants. One of those organisms is the blue mussel, which uses certain enzymes in its stomach to break down sugar fibers in the algae that it eats. But how does this really work, and can we use it for anything? Plant cells have very strong walls, protecting them from environmental stress.

Straffteori i amerikansk och svensk rätt - Proportionalitet, prevention eller humanitet? En studie på lagstiftnings- och domstolsnivå

Uppsatsen behandlar proportionalitet och straffteori utifrån ett amerikanskt respektive ett svenskt perspektiv. Uppsatsen utgår från en indelning som typiskt görs för att indela straffrättssystemet och avhandlar amerikansk respektive svensk straffteori utifrån ett lagstiftnings- och ett domstolsperspektiv. Det bör understrykas att uppsatsen inte är någon komparation mellan rättsystemen, utan snaraThis essay concerns the issue of proportionality in penal theory as it is applied in USA and in Sweden. The essay compares two main aspects, or levels of this proportionality; the judicial level and the court level, of each jurisdiction respectively; applying the comparative method. The essay thus addresses the federal system of American jurisprudence, and the interpreting and guiding role of th

Utvärdering av ankomstprognoser för tåg

I detta examensarbete görs en utvärdering av ankomstprognoser för tåg för att se hur de olika prediktionskällorna står sig mot varandra och hur pass väl dessa efterspeglar verkligheten. Vidare är detta examensarbete en sprint av ett forskningsprojekt som genomförs och bedrivs på Lunds Tekniska Högskola på uppdrag av Trafikverket. Till skillnad från forskningsprojektet bygger detta examensarbetIn this master thesis, an evaluation of arrival forecasts for trains is made to see how various prediction sources compare to each other and how well these reflect reality. Furthermore, this thesis is a sprint of a research project that is carried out and conducted at Lund University of Technology on behalf of the Swedish Transport Administration. Unlike the research project, this thesis is based

The interaction of Pseudomonas aeruginosa clinical isolates and human monoclonal antibodies

The invaders vs. the protectors: who wins the battle? Pseudomonas aeruginosa or in short PsA is a type of microorganism, also known as “bacteria” or “germ” or “bug”. It is very tiny and invisible to our naked eyes. This germ is found everywhere in places like soil, and water. PsA can get into the human body through wounds and other injuries and make people sick. To prevent humans from getting inf

Mating system, female fecundity and sexual selection in wild Cassida viridis beetles

What makes a beetle attractive? My project looks at how green tortoise beetles (Cassida viridis) choose partners, and which physical traits have a higher success in obtaining a mate. I did this by tracking individuals in three wild populations of Skåne, Sweden, and taking photographs of mating beetles. To document differences between the sexes and populations, see how many partners a beetle has,

Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA1c levels but not with type 2 diabetes

Aims/hypothesis: An intronic variant (rs10830963) in MTNR1B (encoding the melatonin receptor type 2 [MT2]) has been shown to strongly associate with impaired glucose regulation and elevated type 2 diabetes prevalence. However, MTNR1B missense variants have shown conflicting results on type 2 diabetes. Thus, we aimed to gain further insights into the impact of MTNR1B coding variants on type 2 diabe

Action-plan-for-Lund-Universitys-collaboration-with-Europe2021-2024

Brevmall Vice-chancel lor Action plan for Lund University’s collaboration with Europe 2021-2024 Approved by the vice-chancellor on 18 December 2020 The process that has resulted in the action plan LU’s External Relations division was tasked with coordinating the work on producing an action plan for Lund University’s collaboration with Europe 2021-2024. The action plan was drawn up in consultation

https://www.staff.lu.se/sites/staff.lu.se/files/2021-07/Action-plan-for-Lund-Universitys-collaboration-with-Europe2021-2024.pdf - 2026-06-12