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BACKGROUND: Healthy lifestyle habits (regular physical activity, a healthy diet, no smoking and non-hazardous alcohol consumption) alongside pharmacological treatment can lower the risk of cardiovascular diseases and improve symptoms and quality of life in patients with rheumatoid arthritis (RA). Therefore, healthcare professionals in rheumatology care are urged to discuss lifestyle habits with al

Trusted Third Parties (TTPs) are a standard building block in secure systems and are used in many cryptographic protocols. A TTP is an entity which facilitates interaction between the users in a system. As the name suggests, TTPs are trusted, and can thus be relied on to perform critical parts of a protocol without need for external scrutiny. Due to this property, they can serve the role of making

BACKGROUND: The aim of this study was to investigate how much perfusion pressure an artery can tolerate without significant loss of endothelium-dependent relaxation (EDR) and vascular contractility. METHODS: The abdominal aortas of 396 Sprague-Dawley rats were used. One hundred twenty aortas were flush-perfused for 1 or 5 minutes with cold St. Thomas' Hospital cardioplegic (STHC) solution or with

High-Arctic environments are facing an elevated pace of warming and increasing human activities, making them more susceptible to the introduction and spread of alien species. We investigated the role of human disturbance in facilitating the spread of a native plant (Papaver dahlianum) in a high-Arctic natural environment close to Isfjord Radio station and along adjacent hiking trails at Kapp Linné

The glabrous skin around the nostrils in mammals is called a rhinarium or planum nasale. Rhinarium skin has multiple epidermal domes that are generally assumed to form a tactile surface. The rhinarium is innervated by a branch of the trigeminal nerve which is associated with stimuli such as touch, chemical irritants and temperature. In this study, our aim was to correlate variation in rhinarium sk

The antiproton experiment PANDA at FAIR is designed to bring hadron physics to a new level in terms of scope, precision and accuracy. In this work, its unique capability for studies of hyperons is outlined. We discuss ground-state hyperons as diagnostic tools to study non-perturbative aspects of the strong interaction, and fundamental symmetries. New simulation studies have been carried out for tw

In this chapter, an alternative surface flow algorithm is presented. The basic idea behind the algorithm is the use of the advantages of TIN-based algorithms within a raster based environment. A gridded raster DEM is used to create a ‘regular TIN’, over which surface flow is estimated. Since each facet in the TIN has a constant slope and slope direction, the estimations of, for example, flow veloc

Recognizing diversity within everyone’s lived experience:Strengthening the theoretical foundations of Universal DesignThis paper situates Universal Design (UD) within the framework ofsocial justice theory, drawing Honneth’s conceptualisation of socialjustice as mutual recognition. It takes as a starting point theperspective that UD requires a robust theorisation and rationale tosupport implementat

Introduction Severe osteogenesis imperfecta (OI) is a debilitating disease with no cure or sufficiently effective treatment. Mesenchymal stem cells (MSCs) have good safety profile, show promising effects and can form bone. The Boost Brittle Bones Before Birth (BOOSTB4) trial evaluates administration of allogeneic expanded human first trimester fetal liver MSCs (BOOST cells) for OI type 3 or severe

Metal implants, in e.g. joint replacements, are generally considered to be a success. As mechanical stability is important for the longevity of a prosthesis, the biological reaction of the bone to the mechanical loading conditions after implantation and during remodelling determines its fate. The bone reaction at the implant interface can be studied using high-resolution imaging. However, commonly

In this article, the convergence of quantum mechanical (QM) free-energy simulations based on molecular dynamics simulations at the molecular mechanics (MM) level has been investigated. We have estimated relative free energies for the binding of nine cyclic carboxylate ligands to the octa-acid deep-cavity host, including the host, the ligand, and all water molecules within 4.5 Å of the ligand in th

In On What Matters (2011) Derek Parfit advocates the Kantian Contractualist Formula as one of three supreme moral principles. In important cases, this formula entails that it is wrong for an agent to act in a way that would be partially best. In contrast, Parfit’s wide value-based objective view of reasons entails that the agent often have sufficient reasons to perform such acts. It seems then tha

Transplants of fetal midbrain raphe neurons into the adult brain have been shown to promote recovery of complex behavioral deficits in several experimental models, but the mechanisms underlying these effects are only partially understood. In the present study, we have used a well-characterized model system to ascertain whether midbrain raphe graft can display behaviorally relevant changes in trans

Plant-based beverages are increasing in popularity and quinoa is an attractive option. A hygienic implication linked to the production of beverages from raw material originating from plants is the high microbial contamination. The safety of the product can be guaranteed by lactic acid fermentation, and by using a probiotic strain as starter culture for the fermentation, the final product will bene

Patients in intensive care suffer from severe illnesses or injuries and from symptoms related to care and treatments. Environmental factors, such as lighting at night, can disturb patients’ circadian rhythms. The aim was to investigate whether patients displayed circadian rhythms and whether a cycled lighting intervention would impact it. In this pilot study (N = 60), a cycled lighting interventio

Creating nutritious and ecologically regenerative food cultures depends on the local knowledge of food system laborers. Food producers in small island developing states center socioecological interdependence in their livelihoods and, as such, conserve biocultural diversity. Amid burgeoning health, economic, and climate crises brought on by colonialism, reclaiming food sovereignty requires a critic

In this study a multilocus phylogenetic analysis of metalmark moths (Lepidoptera: Choreutidae) focused on resolving the higher-level phylogeny of this group is presented. Through the analysis of this dataset, I explore different data-partitioning strategies in Bayesian phylogenetic inference, and find that a partitioning strategy can have a large influence on the results of phylogenetic analysis.

This report is a fire safety evaluation of Norrbottensteatern in Luleå, Sweden. The report was carried out as a part of the education program for fire engineers. The main purpose was to analyse the safety regarding evacuation in case of fire, and to present a proposal of measures if necessary. The theatre, built in 1986, is a four storey building and can hold more than 600 guests in its three salo

Malmö har utvecklats från att vara en industristad förr till att idag profilera sig som kunskaps- och evenemangstad. I takt med att nya visioner och mål satts upp finner man ett genomgående tema staden arbetar starkt för – en hållbar utveckling. En hållbar utveckling skall skapa det attraktiva Malmö, dit fler människor vill söka sig. För att uppnå visionen om att bli en mer hållbar stad beskriver Malmö has evolved from being an industrial city to its current profile as a knowledge and event city. As new visions and objectives are being set, there is a common theme which the city works very strongly for – a sustainable development. This essay aims to investigate the accessibility to and with public transports in Malmö in view of the city’s objective to decrease the use of cars, increase the