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This thesis describes functional studies of the human protein alpha-1-microglobulin (A1M), with the aim of exploring its usefulness as a therapeutic agent in diseases where oxidative stress is a prominent feature. A1M is a 26 kDa plasma and tissue protein with reductase activity and radical- and heme-binding antioxidative functions. The research focus in this thesis has been to study the in vivo p
Bortezomib is a highly selective inhibitor of the 26S proteasome and has been approved for clinical use in the treatment of relapsing and refractory multiple myeloma and mantle cell lymphoma. Clinical trials are also underway to assess the role of bortezomib in several other human malignancies, including leukemia. However, the mechanism(s) by which bortezomib acts remain to be fully understood. He
BACKGROUND: Newborn infants undergoing intensive care are at risk of bleeding and thrombotic complications. Fresh frozen plasma (FFP) is used in hope of preventing these complications, despite poorly defined effects on the coagulation system and lack of proven clinical efficacy. OBJECTIVES AND METHODS: We prospectively evaluated coagulopathy and the effect of standardized amount of FFP transfusion
Background: BARD1 was originally identified as a BRCA1- interacting protein but has also been described in tumour-suppressive functions independent of BRCA1. Several studies have indicated that the BARD1 gene is a potential target for germline changes predisposing to breast and ovarian cancer. The C- terminal Cys557Ser change has previously been uncovered to associate with an increased risk of bre
Background: Club cell secretory protein (CC16) probably has a role in protecting the lung from inflammation. Aim: To evaluate if low levels of CC16 in gastric fluid at birth, reflecting low levels of CC16 in the lung, would be associated with lung inflammation and respiratory morbidity. Methods: A study of 64 infants with mean gestational age 26.1 weeks. CC16 was analyzed in gastric fluid at birth
AIMS: Metabolic derangement is implicated in the pathophysiology of heart failure (HF) and pulmonary hypertension (PH). We aimed to identify the dynamics of metabolic plasma proteins linked to end-stage HF and associated PH in relation to haemodynamics, before and after heart transplantation (HT).METHODS AND RESULTS: Twenty-one metabolic plasma proteins were analysed with proximity extension assay
Ocular injury in the rabbit causes miosis and breakdown of the blood aqueous barrier (aqueous flare response, AFR), reflecting a sensory nerve-mediated inflammatory response, elicited by the release of tachykinins and calcitonin gene-related peptide (CGRP) from C-fibers. Neuropeptide Y (NPY) occurs in sympathetic fibers in the eye. The study was designed to examine whether NPY and related peptides
DC210422_proof.pdf Laura M. Jacobsen,1 Kendra Vehik,2 Riitta Veijola,3 Katharina Warncke,4 Jorma Toppari,5,6 Andrea K. Steck,7 Patricia Gesualdo,7 Beena Akolkar,8 Markus Lundgren,9 William A. Hagopian,10 Jin-Xiong She,11 Marian Rewers,7 Anette G. Ziegler,3 Jeffrey P. Krischer,2 Helena Elding Larsson,9 and Michael J. Haller,1 the TEDDY Study Group* Heterogeneity of DKA Incidence and Age-Specific Cl
https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-01/138%20MP171_Jacobsen_Diab%20Care_2022.pdf - 2026-05-01
Distributed Economies_FINAL02 A Vision of Sustainable Economies Is Distributed Future The The International Institute for Industrial Environmental Economics at Lund University MESPOM Masters of Environmental Sciences, Policy and Management “The Future is distributed: a vision of sustainable economies” is a collection of case studies on distributed economies, a concept describing sustainable altern
https://www.iiiee.lu.se/sites/iiiee.lu.se/files/distributed_economies_mespom_2009.pdf - 2026-05-01
2007:11 Statliga myndigheters hantering av programvarulicenser MISSIV POSTADRESS: Box 8110, 104 20 Stockholm. BESÖKSADRESS: Fleminggatan 20. TELEFON VXL: 08-454 46 00. FAX: 08-791 89 72. statskontoret@statskontoret.se www.statskontoret.se DATUM DIARIENR 2007-06-29 2006/261 ERT DATUM ER BETECKNING 2006-12-07 Ju2005/4827/L3 Regeringen Justitiedepartementet 103 33 Stockholm Uppdrag att utreda statlig
https://www.it.lu.se/sites/it.lu.se/files/programformedling_statskontoret_2007_11.pdf - 2026-05-01
untitled ORIGINAL CONTRIBUTION Plasma Proneurotensin and Incidence of Diabetes, Cardiovascular Disease, Breast Cancer, and Mortality Olle Melander, MD, PhD Alan S. Maisel, MD Peter Almgren, MSc Jonas Manjer, MD, PhD Mattias Belting, MD, PhD Bo Hedblad, MD, PhD Gunnar Engström, MD, PhD Ute Kilger, PhD Peter Nilsson, MD, PhD Andreas Bergmann, PhD Marju Orho-Melander, PhD BARIATRIC SURGERY OF PA- ti
https://www.epihealth.lu.se/sites/epihealth.lu.se/files/jama_neurotensin_2012.pdf - 2026-05-01
I ett års tid har jag levt vid sidan av konsumtionssamhället. [. . .] Barnen ska få sina julklappar. Dock ett litet antal. Jag ska i varje fall göra processen kort, för jag vill inte in i affärerna. Nu har den rena viljeakten att inte gå in övergått i ett fysiskt motstånd. Bara tanken på en runda på Drottninggatan gör kroppen tung som bly. Jag har det inte i mig längre.1 en här bekännelsen är hämt
https://www.ses.lu.se/sites/ses.lu.se/files/kp-2016-2_fredriksson.pdf - 2026-05-01
Professor emeritus Kontaktinformation E-post: ulf [dot] elg [at] fek [dot] lu [dot] seOrganisation Marknadsföring Hämtställe: 10 WebbplatsUlf Elgs profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftBokDel av eller Kapitel i bokKonferens - annatKonferensbidragRapportUndervisningsfallWorking p
https://www.ehl.lu.se/ulf-elg - 2026-04-30
Background Patients with severe hemophilia A and factor VIII inhibitors are at increased risk for serious bleeding complications and progression to end-stage joint disease. Effective strategies to prevent bleeding in such patients have not yet been established. Methods We enrolled patients with hemophilia A who were older than 2 years of age, had high-titer inhibitors, and used concentrates known
AIMS: Red cell distribution width (RDW) has been associated with cardiovascular disease, but the relation to heart failure (HF) is unclear. We investigated the association between RDW and incidence of first hospitalization due to HF in a population-based cohort. METHODS AND RESULTS: Red cell distribution width was measured in 26 784 subjects (aged 45-73 years, 61% women), without history of myocar
BACKGROUND: There are conflicting data on whether changes in N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hs-CRP) concentrations between time points (delta NT-proBNP and hs-CRP) are associated with a change in prognosis. METHODS: We measured NT-proBNP and hs-CRP at 3 time points in 1665 patients with non-ST-segment elevation acute coronary syndrome
Kursguide - Course Syllabus Books Anderson, Bridget (2015). Us and Them? The Dangerous Politics of Immigration Control. Oxford: OUP. 224 pages. ISBN: 978-0-198-73761-2 Betts, Alexander (Ed) (2012). Global Migration Governance. Oxford University Press. 368 pages, selected chapters. ISBN: 978-0-199-65380-5 Brettell, Caroline B. & James F. Hollifeld (2015). Migration Theory: Talking Across Discipline
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sims26_english_litteratur_16010_h16.pdf - 2026-05-01
Kursguide - Course Syllabus Books Anderson, Bridget (2015). Us and Them? The Dangerous Politics of Immigration Control. Oxford: OUP. 224 pages. ISBN: 978-0-198-73761-2 Betts, Alexander (Ed) (2012). Global Migration Governance. Oxford University Press. 368 pages, selected chapters. ISBN: 978-0-199-65380-5 Brettell, Caroline B. & James F. Hollifeld (2015). Migration Theory: Talking Across Discipline
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sims26_granskad_litteratur_16010_h16.pdf - 2026-05-01
Program ESSUG:s användardagar 2022 via Zoom Tisdagen den 26 april (EBSCO deltar under denna eftermiddag) 13.00-13.05 Välkomna! 13.05-13.45 Presentation the new GOPAC/Global OPAC (Claus Wolf, Manager Library Service Engineer team) 30 min + 10 min frågor 13.45-13.50 Paus 13.50-14.20 Continued roll out and enhancements of the new EDS interface. Project updates (PM- team) 20 min + 10 min frågor 14.20-
https://www.ub.lu.se/sites/ub.lu.se/files/2022-05/Program%20ESSUG%20anv%C3%A4ndardagar%2026-27%20april.pdf - 2026-05-01
Brevmall Postadress Box 117, 221 00 Lund, Besöksadress Allhelgona kyrkogata 14 M, Telefonväxeln 046-222 00 00 Webbadress http//:graduateschool.sam.lu.se Department o f Gender S tudies Litteraturlista GNVB10 Det jämlika vårdmötet, 7,5 hp Axelsson Fisk, S., Ekberg Jansson, A., Stridsman, C., & Merlo, J. (2021). Socioekonomiska riskfaktorer bör beaktas i kvalitetsregister. Lakartidningen, 6-7/2021. 2
https://www.genus.lu.se/sites/genus.lu.se/files/2021-06/GNVB10%20HT21.pdf - 2026-05-01
